AHDC1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: AHDC1_HUMAN
• UniProt AC: Q5TGY3
• Protein Name: AT-hook DNA-binding motif-containing protein 1
• Gene Name: AHDC1
• Organism: Homo sapiens (Human).
• Sequence Length: 1603
• Protein Sequence: MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFLHRVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	KPQGLVVTSSAVCSS CCCCEEEECCCCCCC	14.97	28348404
12	Phosphorylation	PQGLVVTSSAVCSSP CCCEEEECCCCCCCC	12.51	28348404
13	Phosphorylation	QGLVVTSSAVCSSPD CCEEEECCCCCCCCH	18.50	28348404
17	Phosphorylation	VTSSAVCSSPDYLRE EECCCCCCCCHHHCC	38.00	24719451
18	Phosphorylation	TSSAVCSSPDYLREP ECCCCCCCCHHHCCC	19.36	28348404
27	Phosphorylation	DYLREPKYYPGGPPT HHHCCCCCCCCCCCC	26.13	28634298
28	Phosphorylation	YLREPKYYPGGPPTP HHCCCCCCCCCCCCC	11.09	28634298
34	Phosphorylation	YYPGGPPTPRPLLPT CCCCCCCCCCCCCCC	34.75	101545463
41	Phosphorylation	TPRPLLPTRPPASPP CCCCCCCCCCCCCCC	56.64	22167270
46	Phosphorylation	LPTRPPASPPDKAFS CCCCCCCCCCCCHHH	42.62	22167270
70	Phosphorylation	PPPRRDPSTRRPPVL CCCCCCCCCCCCCCC	38.54	22817900
79	Acetylation	RRPPVLAKGDDPLPP CCCCCCCCCCCCCCC	59.73	26051181
99	Phosphorylation	VSQARCPTPVGDGSS CCCCCCCCCCCCCCC	33.94	26657352
105	Phosphorylation	PTPVGDGSSSRRCWD CCCCCCCCCCCCCCC	29.85	27251275
106	Phosphorylation	TPVGDGSSSRRCWDN CCCCCCCCCCCCCCC	33.13	27251275
107	Phosphorylation	PVGDGSSSRRCWDNG CCCCCCCCCCCCCCC	25.99	27251275
132	Phosphorylation	IDIMKDLTRLSQDLQ HHHHHHHHHHHHHHH	39.43	24247654
135	Phosphorylation	MKDLTRLSQDLQHSG HHHHHHHHHHHHHCC	20.54	113320301
141	Phosphorylation	LSQDLQHSGVHLDCG HHHHHHHCCCCEECC	29.56	27050516
151	Methylation	HLDCGGLRLSRPPAP CEECCCEEECCCCCC	33.61	-
154	Methylation	CGGLRLSRPPAPPPG CCCEEECCCCCCCCC	45.90	-
169	Phosphorylation	DLQYSFFSSPSLANS CCCEEECCCHHHHHH	39.05	23898821
170	Phosphorylation	LQYSFFSSPSLANSI CCEEECCCHHHHHHC	17.22	23898821
172	Phosphorylation	YSFFSSPSLANSIRS EEECCCHHHHHHCCC	41.90	23898821
176	Phosphorylation	SSPSLANSIRSPEER CCHHHHHHCCCHHHH	17.48	28102081
179	Phosphorylation	SLANSIRSPEERATP HHHHHCCCHHHHCCC	34.69	28348404
198	Phosphorylation	ERPSHPLYEPEPEPR CCCCCCCCCCCCCCC	33.61	27642862
268	Phosphorylation	AQALEPPSPEPEPQL HHCCCCCCCCCCCCC	53.24	24275569
369	Phosphorylation	PLRLDLCSPHGPPGP CEEEEECCCCCCCCC	27.51	28985074
458	Phosphorylation	LKPESSQTPVVSTRK CCCCCCCCCCEECCC	21.72	15996615
462	Phosphorylation	SSQTPVVSTRKGKCR CCCCCCEECCCCCCC	23.80	15996167
463	Phosphorylation	SQTPVVSTRKGKCRG CCCCCEECCCCCCCC	25.45	15996175
484	Phosphorylation	KMAKIPVSLGRRNKT HHHCCCHHHCCCCCC	21.54	28555341
491	Phosphorylation	SLGRRNKTTYKVSSL HHCCCCCCEEEEEEC	38.62	63766001
492	Phosphorylation	LGRRNKTTYKVSSLS HCCCCCCEEEEEECC	23.97	63766007
493	Phosphorylation	GRRNKTTYKVSSLSS CCCCCCEEEEEECCC	18.02	23911959
500	Phosphorylation	YKVSSLSSSLSVEGK EEEEECCCCEEECCE	40.36	25159151
501	Phosphorylation	KVSSLSSSLSVEGKE EEEECCCCEEECCEE	22.68	21130716
503	Phosphorylation	SSLSSSLSVEGKELG EECCCCEEECCEECC	21.77	113320309
507	Ubiquitination	SSLSVEGKELGLRVS CCEEECCEECCEEEE	35.94	-
518	Phosphorylation	LRVSAEPTPLLKMKN EEEECCCCCCEEECC	20.34	24719451
560	Ubiquitination	NLLLGPGKPKEPAVV CCEECCCCCCCCHHH	56.93	29967540
593	Ubiquitination	KRRRRKQKLASPQPS HHHHHHHHHCCCCCC	49.40	29967540
596	Phosphorylation	RRKQKLASPQPSYAA HHHHHHCCCCCCCCC	34.21	29255136
600	Phosphorylation	KLASPQPSYAADAND HHCCCCCCCCCCCCC	23.35	30266825
601	Phosphorylation	LASPQPSYAADANDS HCCCCCCCCCCCCCC	16.70	22199227
609	Sumoylation	AADANDSKAEYSDVL CCCCCCCHHHHHHHH	48.37	28112733
609	Ubiquitination	AADANDSKAEYSDVL CCCCCCCHHHHHHHH	48.37	29967540
612	Phosphorylation	ANDSKAEYSDVLAKL CCCCHHHHHHHHHHH	18.28	110752789
613	Phosphorylation	NDSKAEYSDVLAKLA CCCHHHHHHHHHHHH	16.85	110752797
626	Phosphorylation	LAFLNRQSQCAGRCS HHHHCCCCCCCCCCC	24.80	22210691
633	Phosphorylation	SQCAGRCSPPRCWTP CCCCCCCCCCCCCCC	36.26	23403867
639	Phosphorylation	CSPPRCWTPSEPESV CCCCCCCCCCCCCCC	22.14	30108239
641	Phosphorylation	PPRCWTPSEPESVHQ CCCCCCCCCCCCCCC	59.41	35095537
645	Phosphorylation	WTPSEPESVHQAPDT CCCCCCCCCCCCCCC	35.30	27251275
652	Phosphorylation	SVHQAPDTQSISHFL CCCCCCCCHHHHHHH	24.13	27251275
654	Phosphorylation	HQAPDTQSISHFLHR CCCCCCHHHHHHHHH	28.31	27251275
678	Methylation	KAGGFGGRGGGHAAK CCCCCCCCCCHHHHH	40.75	-
690	Phosphorylation	AAKSARCSFSDFFEG HHHHCCCCHHHHHCC	23.41	23403867
692	Phosphorylation	KSARCSFSDFFEGIG HHCCCCHHHHHCCCC	19.74	23403867
700	Acetylation	DFFEGIGKKKKVVAV HHHCCCCCCCEEEEE	60.54	25953088
737	Acetylation	EVDAVTGKPKRKRRS CCCCCCCCCCCCCCC	37.69	25953088
737	Ubiquitination	EVDAVTGKPKRKRRS CCCCCCCCCCCCCCC	37.69	29967540
746	Ubiquitination	KRKRRSRKNGTLFPE CCCCCCCCCCCCCCC	62.06	29967540
803	O-linked_Glycosylation	TEARAFASTGLESGA HHHHHHHCCCCCCCC	19.29	28657654
826	Phosphorylation	TGAPSGQTELSQERQ CCCCCCCCHHHHHHH	42.28	27732954
829	Phosphorylation	PSGQTELSQERQNLF CCCCCHHHHHHHHHH	24.62	17525332
839	Phosphorylation	RQNLFTGYFRSLLDS HHHHHHHHHHHHCCC	7.86	8281721
842	Phosphorylation	LFTGYFRSLLDSDDS HHHHHHHHHCCCCCH	24.32	28450419
846	Phosphorylation	YFRSLLDSDDSSDLL HHHHHCCCCCHHHHH	43.20	22617229
849	Phosphorylation	SLLDSDDSSDLLDFA HHCCCCCHHHHHHHH	30.64	22617229
850	Phosphorylation	LLDSDDSSDLLDFAL HCCCCCHHHHHHHHH	38.99	22115753
858	Phosphorylation	DLLDFALSASRPESR HHHHHHHHCCCCCHH	22.29	20873877
860	Phosphorylation	LDFALSASRPESRKA HHHHHHCCCCCHHHC	45.02	28102081
864	Phosphorylation	LSASRPESRKASGTY HHCCCCCHHHCCCCC	41.59	25841592
868	Phosphorylation	RPESRKASGTYAGPP CCCHHHCCCCCCCCC	34.40	28857561
870	Phosphorylation	ESRKASGTYAGPPTS CHHHCCCCCCCCCCC	14.01	32142685
871	Phosphorylation	SRKASGTYAGPPTSA HHHCCCCCCCCCCCC	17.06	28555341
876	Phosphorylation	GTYAGPPTSALPAQR CCCCCCCCCCCCHHH	29.75	28102081
877	Phosphorylation	TYAGPPTSALPAQRG CCCCCCCCCCCHHHC	33.31	28555341
887	Phosphorylation	PAQRGLATFPSRGAK CHHHCCCCCCCCCCC	40.91	27251275
890	Phosphorylation	RGLATFPSRGAKASP HCCCCCCCCCCCCCC	38.87	28555341
891	Methylation	GLATFPSRGAKASPV CCCCCCCCCCCCCCE	49.69	24129315
894	Sumoylation	TFPSRGAKASPVAVG CCCCCCCCCCCEEEC	52.82	-
894	Sumoylation	TFPSRGAKASPVAVG CCCCCCCCCCCEEEC	52.82	-
894	Ubiquitination	TFPSRGAKASPVAVG CCCCCCCCCCCEEEC	52.82	29967540
896	Phosphorylation	PSRGAKASPVAVGSS CCCCCCCCCEEECCC	21.14	29255136
902	Phosphorylation	ASPVAVGSSGAGADP CCCEEECCCCCCCCC	20.99	29255136
903	Phosphorylation	SPVAVGSSGAGADPS CCEEECCCCCCCCCC	27.08	23403867
910	Phosphorylation	SGAGADPSFQPVLSA CCCCCCCCCHHCCCC	36.74	23403867
916	Phosphorylation	PSFQPVLSARQTFPP CCCHHCCCCCCCCCC	22.95	23403867
928	Phosphorylation	FPPGRAASYGLTPAA CCCCCHHHCCCCCCH	20.81	113320317
943	Phosphorylation	SDCRAAETFPKLVPP HHCHHHHHCCCCCCC	40.28	113320325
957	Phosphorylation	PPSAMARSPTTHPPA CCHHHCCCCCCCCCC	19.63	23663014
959	Phosphorylation	SAMARSPTTHPPANT HHHCCCCCCCCCCCC	38.70	23663014
960	Phosphorylation	AMARSPTTHPPANTY HHCCCCCCCCCCCCC	35.45	23663014
966	Phosphorylation	TTHPPANTYLPQYGG CCCCCCCCCCCCCCC	28.65	23663014
967	Phosphorylation	THPPANTYLPQYGGY CCCCCCCCCCCCCCC	19.05	23401153
971	Phosphorylation	ANTYLPQYGGYGAGQ CCCCCCCCCCCCCCC	15.58	23663014
974	Phosphorylation	YLPQYGGYGAGQSVF CCCCCCCCCCCCCCC	10.23	23663014
979	Phosphorylation	GGYGAGQSVFAPTKP CCCCCCCCCCCCCCC	20.48	25072903
984	Phosphorylation	GQSVFAPTKPFTGQD CCCCCCCCCCCCCCC	48.17	25072903
985	Acetylation	QSVFAPTKPFTGQDC CCCCCCCCCCCCCCC	36.75	26051181
995	Phosphorylation	TGQDCANSKDCSFAY CCCCCCCCCCCCEEE	16.02	72250481
999	Phosphorylation	CANSKDCSFAYGSGN CCCCCCCCEEECCCC	24.05	26074081
1002	Phosphorylation	SKDCSFAYGSGNSLP CCCCCEEECCCCCCC	15.15	26074081
1004	Phosphorylation	DCSFAYGSGNSLPAS CCCEEECCCCCCCCC	23.33	26074081
1007	Phosphorylation	FAYGSGNSLPASPSS EEECCCCCCCCCCCC	38.98	26074081
1011	Phosphorylation	SGNSLPASPSSAHSA CCCCCCCCCCCCCCC	24.31	26074081
1013	Phosphorylation	NSLPASPSSAHSAGY CCCCCCCCCCCCCCC	37.35	26074081
1014	Phosphorylation	SLPASPSSAHSAGYA CCCCCCCCCCCCCCC	33.13	46160643
1017	Phosphorylation	ASPSSAHSAGYAPPP CCCCCCCCCCCCCCC	24.09	26074081
1020	Phosphorylation	SSAHSAGYAPPPTGG CCCCCCCCCCCCCCC	18.69	26074081
1025	Phosphorylation	AGYAPPPTGGPCLPP CCCCCCCCCCCCCCC	61.62	26074081
1033	Phosphorylation	GGPCLPPSKASFFSS CCCCCCCHHHCCCCC	38.62	26074081
1052	Phosphorylation	PFSGSAPTPLRCDSR CCCCCCCCCCCCCCC	34.37	25159151
1058	Phosphorylation	PTPLRCDSRASTVSP CCCCCCCCCCCEECC	33.11	22210691
1061	Phosphorylation	LRCDSRASTVSPGGY CCCCCCCCEECCCCE	28.38	30266825
1062	Phosphorylation	RCDSRASTVSPGGYM CCCCCCCEECCCCEE	24.82	30266825
1064	Phosphorylation	DSRASTVSPGGYMVP CCCCCEECCCCEECC	20.23	30266825
1068	Phosphorylation	STVSPGGYMVPKGTT CEECCCCEECCCCCC	10.80	23403867
1095	Phosphorylation	SSSSFQPSPENCRQF CCCCCCCCHHHHHHH	33.78	28985074
1162	Phosphorylation	QQTAVSETFSESSSD HHHHCCCCCCCCCCC	25.59	28348404
1164	Phosphorylation	TAVSETFSESSSDST HHCCCCCCCCCCCCC	43.94	28348404
1166	Phosphorylation	VSETFSESSSDSTQF CCCCCCCCCCCCCCC	33.66	28348404
1167	Phosphorylation	SETFSESSSDSTQFN CCCCCCCCCCCCCCC	33.83	28348404
1168	Phosphorylation	ETFSESSSDSTQFNQ CCCCCCCCCCCCCCC	44.88	28348404
1170	Phosphorylation	FSESSSDSTQFNQPV CCCCCCCCCCCCCCC	26.51	28348404
1171	Phosphorylation	SESSSDSTQFNQPVG CCCCCCCCCCCCCCC	42.02	28348404
1187	Phosphorylation	GGFRRANSEASSSEG CCCCCCCCCCCCCCC	33.29	25159151
1190	Phosphorylation	RRANSEASSSEGQSS CCCCCCCCCCCCCCC	30.28	26657352
1191	Phosphorylation	RANSEASSSEGQSSL CCCCCCCCCCCCCCH	39.18	28450419
1192	Phosphorylation	ANSEASSSEGQSSLS CCCCCCCCCCCCCHH	43.16	26657352
1196	Phosphorylation	ASSSEGQSSLSSLEK CCCCCCCCCHHHHHH	44.07	23312004
1197	Phosphorylation	SSSEGQSSLSSLEKL CCCCCCCCHHHHHHH	25.12	23312004
1199	Phosphorylation	SEGQSSLSSLEKLMM CCCCCCHHHHHHHHC	34.52	27251275
1200	Phosphorylation	EGQSSLSSLEKLMMD CCCCCHHHHHHHHCC	45.93	21815630
1238	Sumoylation	PGRGRRKKVDLFEAS CCCCCCCCCCHHHHH	38.89	-
1238	Sumoylation	PGRGRRKKVDLFEAS CCCCCCCCCCHHHHH	38.89	-
1238	Ubiquitination	PGRGRRKKVDLFEAS CCCCCCCCCCHHHHH	38.89	29967540
1245	Phosphorylation	KVDLFEASHLGFPTS CCCHHHHHHCCCCCC	16.43	23532336
1254	Phosphorylation	LGFPTSASAAASGYP CCCCCCHHHHHCCCC	20.43	23532336
1260	Phosphorylation	ASAAASGYPSKRSTG HHHHHCCCCCCCCCC	11.22	22817900
1281	Phosphorylation	GRGGGACSAKKERGG CCCCCCCCCCCCCCC	42.46	81442355
1286	Methylation	ACSAKKERGGAAAKA CCCCCCCCCCCCCCC	58.69	-
1309	Phosphorylation	VNPLFQDSPDLGLDY CCCCCCCCCCCCCCC	14.99	28122231
1316	Phosphorylation	SPDLGLDYYSGDSSM CCCCCCCCCCCCCCC	12.46	22210691
1317	Phosphorylation	PDLGLDYYSGDSSMS CCCCCCCCCCCCCCC	13.07	28634298
1318	Phosphorylation	DLGLDYYSGDSSMSP CCCCCCCCCCCCCCC	29.87	28634298
1321	Phosphorylation	LDYYSGDSSMSPLPS CCCCCCCCCCCCCCC	31.31	26074081
1322	Phosphorylation	DYYSGDSSMSPLPSQ CCCCCCCCCCCCCCC	28.19	26074081
1324	Phosphorylation	YSGDSSMSPLPSQSR CCCCCCCCCCCCCCC	25.82	26074081
1328	Phosphorylation	SSMSPLPSQSRAFGV CCCCCCCCCCCCCCC	48.77	26074081
1330	Phosphorylation	MSPLPSQSRAFGVGE CCCCCCCCCCCCCCC	29.88	26074081
1352	Phosphorylation	GPYSMNPSTPSDGTF CCCCCCCCCCCCCCC	48.20	28348404
1353	Phosphorylation	PYSMNPSTPSDGTFG CCCCCCCCCCCCCCC	28.24	28348404
1355	Phosphorylation	SMNPSTPSDGTFGQG CCCCCCCCCCCCCCC	49.08	28348404
1358	Phosphorylation	PSTPSDGTFGQGFHC CCCCCCCCCCCCCCC	29.59	28348404
1367	Phosphorylation	GQGFHCDSPSLGAPE CCCCCCCCCCCCCCC	23.06	28348404
1398	Phosphorylation	DAGLQKAYSPTCSPT CCCCCHHCCCCCCCC	23.40	20873877
1399	Phosphorylation	AGLQKAYSPTCSPTL CCCCHHCCCCCCCCC	20.70	22167270
1401	Phosphorylation	LQKAYSPTCSPTLGF CCHHCCCCCCCCCCC	21.48	30266825
1403	Phosphorylation	KAYSPTCSPTLGFKE HHCCCCCCCCCCCCH	24.33	22167270
1405	Phosphorylation	YSPTCSPTLGFKEEL CCCCCCCCCCCCHHH	24.18	30266825
1409	Acetylation	CSPTLGFKEELRPPP CCCCCCCCHHHCCCC	48.78	26051181
1409	Sumoylation	CSPTLGFKEELRPPP CCCCCCCCHHHCCCC	48.78	28112733
1417	Phosphorylation	EELRPPPTKLAACEP HHHCCCCCCCCCCCC	44.45	27251275
1418	Acetylation	ELRPPPTKLAACEPL HHCCCCCCCCCCCCC	41.73	25953088
1456	Phosphorylation	LPLGQPHYDSPSCKG CCCCCCCCCCCCCCC	25.46	11159351
1458	Phosphorylation	LGQPHYDSPSCKGTA CCCCCCCCCCCCCCE	16.14	22199227
1460	Phosphorylation	QPHYDSPSCKGTAYW CCCCCCCCCCCCEEE	32.20	27251275
1464	Phosphorylation	DSPSCKGTAYWYPPG CCCCCCCCEEEECCC	11.32	26074081
1466	Phosphorylation	PSCKGTAYWYPPGSA CCCCCCEEEECCCCH	12.81	26074081
1468	Phosphorylation	CKGTAYWYPPGSAAR CCCCEEEECCCCHHC	6.20	113320333
1472	Phosphorylation	AYWYPPGSAARSPPY EEEECCCCHHCCCCC	25.24	23401153
1476	Phosphorylation	PPGSAARSPPYEGKV CCCCHHCCCCCCCCC	26.04	27794612
1479	Phosphorylation	SAARSPPYEGKVGTG CHHCCCCCCCCCCCH	40.47	28450419
1485	Phosphorylation	PYEGKVGTGLLADFL CCCCCCCCHHHHHHH	27.87	26074081
1495	Phosphorylation	LADFLGRTEAACLSA HHHHHCCHHHHHHCC	28.33	23403867
1501	Phosphorylation	RTEAACLSAPHLASP CHHHHHHCCHHHCCC	39.37	23403867
1507	Phosphorylation	LSAPHLASPPATPKA HCCHHHCCCCCCCCC	37.46	23401153
1511	Phosphorylation	HLASPPATPKADKEP HHCCCCCCCCCCCCC	30.97	25159151
1538	Phosphorylation	PAAAAAGYGCPLLSD HHHHHCCCCCCCCCC	15.72	23403867
1544	Phosphorylation	GYGCPLLSDLTLSPV CCCCCCCCCCCCCCC	37.95	29255136
1547	Phosphorylation	CPLLSDLTLSPVPRD CCCCCCCCCCCCCHH	30.13	26657352
1549	Phosphorylation	LLSDLTLSPVPRDSL CCCCCCCCCCCHHHC	20.72	29255136
1601	Phosphorylation	PEDTFTVTSL----- CCCCCEEECC-----	22.66	28348404
1602	O-linked_Glycosylation	EDTFTVTSL------ CCCCEEECC------	27.96	28657654
1602	Phosphorylation	EDTFTVTSL------ CCCCEEECC------	27.96	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of AHDC1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of AHDC1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of AHDC1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
UBR3_HUMAN	UBR3	physical	26186194
UBR3_HUMAN	UBR3	physical	28514442
TRI68_HUMAN	TRIM68	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 615829: Mental retardation, autosomal dominant 25 (MRD25)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1399 AND SER-1403, ANDMASS SPECTROMETRY.
PubMed: 19413330

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-846; SER-1399 ANDSER-1403, AND MASS SPECTROMETRY.
PubMed: 18669648

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis.";
Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III;
J. Proteome Res. 7:1346-1351(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1549, AND MASSSPECTROMETRY.
PubMed: 18220336

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-829, AND MASSSPECTROMETRY.
PubMed: 17525332

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70, AND MASSSPECTROMETRY.
PubMed: 17081983