dbPTM

RB6I2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RB6I2_HUMAN
UniProt AC	Q8IUD2
Protein Name	ELKS/Rab6-interacting/CAST family member 1
Gene Name	ERC1
Organism	Homo sapiens (Human).
Sequence Length	1116
Subcellular Localization	Cytoplasm. Membrane Peripheral membrane protein. Golgi apparatus membrane Peripheral membrane protein. In neurons, localized closed to presynaptic membrane. Recruited on Golgi membranes by RAB6A in a GTP-dependent manner (By similarity)..
Protein Description	Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport..
Protein Sequence	MYGSARSVGKVEPSSQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSVGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGSETPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLILRGLTPPASYNLDDDQAAWENELQKMTRGQLQDELEKGERDNAELQEFANAILQQIADHCPDILEQVVNALEESS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MYGSARSVG ------CCCCCCCCC	30.96	23090842
4	Phosphorylation	----MYGSARSVGKV ----CCCCCCCCCCC	21.44	25056879
6	Methylation	--MYGSARSVGKVEP --CCCCCCCCCCCCC	33.31	-
7	Phosphorylation	-MYGSARSVGKVEPS -CCCCCCCCCCCCCC	34.63	23927012
10	Acetylation	GSARSVGKVEPSSQS CCCCCCCCCCCCCCC	41.07	25953088
14	Phosphorylation	SVGKVEPSSQSPGRS CCCCCCCCCCCCCCC	27.75	22167270
14 (in isoform 2)	Phosphorylation	-	27.75	-
14 (in isoform 3)	Phosphorylation	-	27.75	-
14 (in isoform 4)	Phosphorylation	-	27.75	-
14 (in isoform 5)	Phosphorylation	-	27.75	-
15	Phosphorylation	VGKVEPSSQSPGRSP CCCCCCCCCCCCCCC	45.45	29255136
15 (in isoform 2)	Phosphorylation	-	45.45	-
15 (in isoform 3)	Phosphorylation	-	45.45	-
15 (in isoform 4)	Phosphorylation	-	45.45	-
15 (in isoform 5)	Phosphorylation	-	45.45	-
17	Phosphorylation	KVEPSSQSPGRSPRL CCCCCCCCCCCCCCC	31.13	29255136
17 (in isoform 2)	Phosphorylation	-	31.13	-
17 (in isoform 3)	Phosphorylation	-	31.13	-
17 (in isoform 4)	Phosphorylation	-	31.13	-
17 (in isoform 5)	Phosphorylation	-	31.13	-
20	Methylation	PSSQSPGRSPRLPRS CCCCCCCCCCCCCCC	47.04	-
21	Phosphorylation	SSQSPGRSPRLPRSP CCCCCCCCCCCCCCC	21.93	29255136
21 (in isoform 2)	Phosphorylation	-	21.93	-
21 (in isoform 3)	Phosphorylation	-	21.93	-
21 (in isoform 4)	Phosphorylation	-	21.93	-
21 (in isoform 5)	Phosphorylation	-	21.93	-
27	Phosphorylation	RSPRLPRSPRLGHRR CCCCCCCCCCCCCCC	16.66	28355574
27 (in isoform 2)	Phosphorylation	-	16.66	-
27 (in isoform 3)	Phosphorylation	-	16.66	-
27 (in isoform 4)	Phosphorylation	-	16.66	-
27 (in isoform 5)	Phosphorylation	-	16.66	-
35	Phosphorylation	PRLGHRRTNSTGGSS CCCCCCCCCCCCCCC	33.21	28176443
35 (in isoform 2)	Phosphorylation	-	33.21	-
35 (in isoform 3)	Phosphorylation	-	33.21	-
35 (in isoform 4)	Phosphorylation	-	33.21	-
35 (in isoform 5)	Phosphorylation	-	33.21	-
37	Phosphorylation	LGHRRTNSTGGSSGS CCCCCCCCCCCCCCC	28.02	27273156
38	Phosphorylation	GHRRTNSTGGSSGSS CCCCCCCCCCCCCCC	47.86	27273156
41	Phosphorylation	RTNSTGGSSGSSVGG CCCCCCCCCCCCCCC	32.63	28176443
42	Phosphorylation	TNSTGGSSGSSVGGG CCCCCCCCCCCCCCC	46.07	28176443
42 (in isoform 2)	Phosphorylation	-	46.07	-
42 (in isoform 3)	Phosphorylation	-	46.07	-
42 (in isoform 4)	Phosphorylation	-	46.07	-
42 (in isoform 5)	Phosphorylation	-	46.07	-
44	Phosphorylation	STGGSSGSSVGGGSG CCCCCCCCCCCCCCC	24.65	20068231
45	Phosphorylation	TGGSSGSSVGGGSGK CCCCCCCCCCCCCCC	28.45	20068231
50	Phosphorylation	GSSVGGGSGKTLSME CCCCCCCCCCCCCHH	40.15	20068231
53	Phosphorylation	VGGGSGKTLSMENIQ CCCCCCCCCCHHHHH	27.82	25159151
55	Phosphorylation	GGSGKTLSMENIQSL CCCCCCCCHHHHHHH	29.31	23401153
55 (in isoform 2)	Phosphorylation	-	29.31	-
55 (in isoform 3)	Phosphorylation	-	29.31	-
55 (in isoform 4)	Phosphorylation	-	29.31	-
55 (in isoform 5)	Phosphorylation	-	29.31	-
61	Phosphorylation	LSMENIQSLNAAYAT CCHHHHHHHHHHHHC	21.57	27080861
66	Phosphorylation	IQSLNAAYATSGPMY HHHHHHHHHCCCCEE	14.17	23090842
68	Phosphorylation	SLNAAYATSGPMYLS HHHHHHHCCCCEECC	22.88	27080861
69	Phosphorylation	LNAAYATSGPMYLSD HHHHHHCCCCEECCC	32.50	27080861
73	Phosphorylation	YATSGPMYLSDHENV HHCCCCEECCCCCCC	13.24	22199227
75	Phosphorylation	TSGPMYLSDHENVGS CCCCEECCCCCCCCC	21.31	27422710
82	Phosphorylation	SDHENVGSETPKSTM CCCCCCCCCCCCCCE	33.73	22199227
84	Phosphorylation	HENVGSETPKSTMTL CCCCCCCCCCCCEEC	37.40	22199227
90	Phosphorylation	ETPKSTMTLGRSGGR CCCCCCEECCCCCCC	26.58	28857561
93	Methylation	KSTMTLGRSGGRLPY CCCEECCCCCCCCCC	34.93	-
94	Phosphorylation	STMTLGRSGGRLPYG CCEECCCCCCCCCCC	43.74	25159151
94 (in isoform 2)	Phosphorylation	-	43.74	-
94 (in isoform 3)	Phosphorylation	-	43.74	-
94 (in isoform 4)	Phosphorylation	-	43.74	-
94 (in isoform 5)	Phosphorylation	-	43.74	-
100	Phosphorylation	RSGGRLPYGVRMTAM CCCCCCCCCEEEEEC	32.61	23186163
105	Phosphorylation	LPYGVRMTAMGSSPN CCCCEEEEECCCCCC	11.70	22210691
109	Phosphorylation	VRMTAMGSSPNIASS EEEEECCCCCCCCCC	29.54	22210691
110	Phosphorylation	RMTAMGSSPNIASSG EEEECCCCCCCCCCC	19.08	20068231
110 (in isoform 2)	Phosphorylation	-	19.08	-
110 (in isoform 3)	Phosphorylation	-	19.08	-
110 (in isoform 4)	Phosphorylation	-	19.08	-
110 (in isoform 5)	Phosphorylation	-	19.08	-
115	Phosphorylation	GSSPNIASSGVASDT CCCCCCCCCCCCCCC	24.67	22210691
116	Phosphorylation	SSPNIASSGVASDTI CCCCCCCCCCCCCCE	28.41	22210691
120	Phosphorylation	IASSGVASDTIAFGE CCCCCCCCCCEEECC	32.64	20068231
122	Phosphorylation	SSGVASDTIAFGEHH CCCCCCCCEEECCCC	16.23	20068231
134	Phosphorylation	EHHLPPVSMASTVPH CCCCCCCCHHHCCCH	17.88	20068231
137	Phosphorylation	LPPVSMASTVPHSLR CCCCCHHHCCCHHHH	22.69	20068231
138	Phosphorylation	PPVSMASTVPHSLRQ CCCCHHHCCCHHHHH	28.63	20068231
142	Phosphorylation	MASTVPHSLRQARDN HHHCCCHHHHHHHHC	21.12	20068231
150	Phosphorylation	LRQARDNTIMDLQTQ HHHHHHCCHHHHHHH	23.20	28857561
177	Phosphorylation	KDVEVKESKLSSSMN CCCHHCHHHHHHHHH	32.93	23403867
181	Phosphorylation	VKESKLSSSMNSIKT HCHHHHHHHHHHHHH	44.00	25159151
182	Phosphorylation	KESKLSSSMNSIKTF CHHHHHHHHHHHHHH	20.71	25627689
188	Phosphorylation	SSMNSIKTFWSPELK HHHHHHHHHCCHHHH	28.77	30266825
191	Phosphorylation	NSIKTFWSPELKKER HHHHHHCCHHHHHHH	12.33	19664994
191 (in isoform 2)	Phosphorylation	-	12.33	-
191 (in isoform 3)	Phosphorylation	-	12.33	-
191 (in isoform 4)	Phosphorylation	-	12.33	-
191 (in isoform 5)	Phosphorylation	-	12.33	-
250	Phosphorylation	NQLFQQDSSSRTGEP HHHHHHCCCCCCCCC	26.35	23663014
251	Phosphorylation	QLFQQDSSSRTGEPC HHHHHCCCCCCCCCC	31.93	23663014
252	Phosphorylation	LFQQDSSSRTGEPCV HHHHCCCCCCCCCCE	37.50	23663014
299	Ubiquitination	ELRIETQKQTLNARD HHHHHHHHHHHHHCH	53.31	-
319	Ubiquitination	LLEMLQSKGLSAKAT HHHHHHHCCCCCCCC	51.41	-
374	Phosphorylation	RFENAPDSAKTKALQ HHHCCCCHHHHHHHH	30.52	21815630
376	2-Hydroxyisobutyrylation	ENAPDSAKTKALQTV HCCCCHHHHHHHHHH	55.28	-
390	2-Hydroxyisobutyrylation	VIEMKDSKISSMERG HHHHCHHHHHHHHHH	57.66	-
390	Acetylation	VIEMKDSKISSMERG HHHHCHHHHHHHHHH	57.66	25953088
392	Phosphorylation	EMKDSKISSMERGLR HHCHHHHHHHHHHHH	27.63	22210691
393	Phosphorylation	MKDSKISSMERGLRD HCHHHHHHHHHHHHH	28.30	22210691
407	Sulfoxidation	DLEEEIQMLKSNGAL HHHHHHHHHHHCCCC	6.64	30846556
410	Phosphorylation	EEIQMLKSNGALSTE HHHHHHHHCCCCCHH	36.21	23312004
415	Phosphorylation	LKSNGALSTEEREEE HHHCCCCCHHHHHHH	32.99	22210691
416	Phosphorylation	KSNGALSTEEREEEM HHCCCCCHHHHHHHH	42.59	21815630
431	Phosphorylation	KQMEVYRSHSKFMKN HHHHHHHHHHHHHHH	17.90	28270605
433	Phosphorylation	MEVYRSHSKFMKNKV HHHHHHHHHHHHHHH	28.92	28270605
448	Phosphorylation	EQLKEELSSKEAQWE HHHHHHHHHHHHHHH	42.52	23403867
488	Ubiquitination	ELLALQTKLETLTNQ HHHHHHHHHHHHHHH	31.22	-
491	Phosphorylation	ALQTKLETLTNQFSD HHHHHHHHHHHHCCC	49.68	21406692
493	Phosphorylation	QTKLETLTNQFSDSK HHHHHHHHHHCCCCH	34.10	21406692
497	Phosphorylation	ETLTNQFSDSKQHIE HHHHHHCCCCHHHHH	31.07	21406692
499	Phosphorylation	LTNQFSDSKQHIEVL HHHHCCCCHHHHHHH	32.77	21406692
500	2-Hydroxyisobutyrylation	TNQFSDSKQHIEVLK HHHCCCCHHHHHHHH	51.38	-
552	Ubiquitination	IQDMAEEKGTQAGEI HHHHHHHHCCCCHHC	59.78	-
554	Phosphorylation	DMAEEKGTQAGEIHD HHHHHHCCCCHHCCC	26.72	23879269
569	Malonylation	LKDMLDVKERKVNVL HHHHHCHHHHHHHHH	52.01	26320211
572	Malonylation	MLDVKERKVNVLQKK HHCHHHHHHHHHHHH	38.97	26320211
579	2-Hydroxyisobutyrylation	KVNVLQKKIENLQEQ HHHHHHHHHHHHHHH	42.14	-
579	Malonylation	KVNVLQKKIENLQEQ HHHHHHHHHHHHHHH	42.14	26320211
590	Acetylation	LQEQLRDKEKQMSSL HHHHHHHHHHHHHHH	61.45	156207
602	Ubiquitination	SSLKERVKSLQADTT HHHHHHHHHHHCCCC	52.23	-
603	Phosphorylation	SLKERVKSLQADTTN HHHHHHHHHHCCCCC	23.90	28857561
625	Ubiquitination	LEEALAEKERTIERL HHHHHHHHHHHHHHH	47.06	-
652	Acetylation	EEIDNYKKDLKDLKE HHHHHHHHHHHHHHH	58.91	7365637
655	Acetylation	DNYKKDLKDLKEKVS HHHHHHHHHHHHHHH	71.76	20167786
658	Acetylation	KKDLKDLKEKVSLLQ HHHHHHHHHHHHHHH	66.67	20167786
669	Phosphorylation	SLLQGDLSEKEASLL HHHHCCCCHHHHHHH	51.90	26437602
671	Ubiquitination	LQGDLSEKEASLLDL HHCCCCHHHHHHHHH	56.03	-
674	Phosphorylation	DLSEKEASLLDLKEH CCCHHHHHHHHHHHH	30.47	27499020
679	2-Hydroxyisobutyrylation	EASLLDLKEHASSLA HHHHHHHHHHHHHHH	47.31	-
679	Ubiquitination	EASLLDLKEHASSLA HHHHHHHHHHHHHHH	47.31	-
687	Phosphorylation	EHASSLASSGLKKDS HHHHHHHHCCCCHHH	30.17	25159151
688	Phosphorylation	HASSLASSGLKKDSR HHHHHHHCCCCHHHH	42.40	25159151
691	Ubiquitination	SLASSGLKKDSRLKT HHHHCCCCHHHHCHH	59.05	-
706	Acetylation	LEIALEQKKEECLKM HHHHHHHHHHHHHHH	53.42	23236377
719	Ubiquitination	KMESQLKKAHEAALE HHHHHHHHHHHHHHH	64.66	-
730	Phosphorylation	AALEARASPEMSDRI HHHHHHCCHHHHHHH	18.81	21815630
734	Phosphorylation	ARASPEMSDRIQHLE HHCCHHHHHHHHHHH	23.29	29523821
736	Methylation	ASPEMSDRIQHLERE CCHHHHHHHHHHHHH	24.14	-
766	Ubiquitination	DRLLEILKEVENEKN HHHHHHHHHHHHHCC	66.43	-
799	Acetylation	KVANLKHKEQVEKKK HHHCHHHHHHHHHHH	48.53	7974731
805	Acetylation	HKEQVEKKKSAQMLE HHHHHHHHHHHHHHH	38.15	7974745
807	Phosphorylation	EQVEKKKSAQMLEEA HHHHHHHHHHHHHHH	32.39	25159151
824	Phosphorylation	REDNLNDSSQQLQDS HHHCCCHHHHHHHHH	29.04	22496350
825	Phosphorylation	EDNLNDSSQQLQDSL HHCCCHHHHHHHHHH	25.47	25159151
831	Phosphorylation	SSQQLQDSLRKKDDR HHHHHHHHHHHHHHH	19.67	28787133
835	Ubiquitination	LQDSLRKKDDRIEEL HHHHHHHHHHHHHHH	59.43	-
858	Sulfoxidation	QITAEREMVLAQEES CHHHHHHHHHHHHHH	3.61	21406390
890	O-linked_Glycosylation	KVKQELESMKAKLSS HHHHHHHHHHHHHHH	37.90	30379171
890	Phosphorylation	KVKQELESMKAKLSS HHHHHHHHHHHHHHH	37.90	29083192
894	Ubiquitination	ELESMKAKLSSTQQS HHHHHHHHHHHHHHH	43.30	-
901	Phosphorylation	KLSSTQQSLAEKETH HHHHHHHHHHHHHHH	21.52	-
905	Ubiquitination	TQQSLAEKETHLTNL HHHHHHHHHHHHHHH	63.41	-
948	Phosphorylation	NIALLELSSSKKKTQ HHHHHHHCCCCCCCH	24.16	28555341
954	Phosphorylation	LSSSKKKTQEEVAAL HCCCCCCCHHHHHHH	50.52	28555341
973	Ubiquitination	DRLVQQLKQQTQNRM HHHHHHHHHHHHHHH	35.70	-
977 (in isoform 3)	Phosphorylation	-	31.06	-
983	Sulfoxidation	TQNRMKLMADNYEDD HHHHHHHHHCCCCCC	3.52	30846556
987	Phosphorylation	MKLMADNYEDDHFKS HHHHHCCCCCCCHHC	22.68	25106551
994	Phosphorylation	YEDDHFKSSHSNQTN CCCCCHHCCCCCCCC	32.13	29523821
995	Phosphorylation	EDDHFKSSHSNQTNH CCCCHHCCCCCCCCC	31.37	29523821
997	Phosphorylation	DHFKSSHSNQTNHKP CCHHCCCCCCCCCCC	32.36	29523821
1000	Phosphorylation	KSSHSNQTNHKPSPD HCCCCCCCCCCCCHH	43.47	29523821
1003	Acetylation	HSNQTNHKPSPDQII CCCCCCCCCCHHHCH	49.62	26051181
1003	Ubiquitination	HSNQTNHKPSPDQII CCCCCCCCCCHHHCH	49.62	-
1005	Phosphorylation	NQTNHKPSPDQIIQP CCCCCCCCHHHCHHH	46.01	18669648
1018 (in isoform 3)	Phosphorylation	-	60.92	-
1046	Phosphorylation	PLILRGLTPPASYNL CCHHCCCCCCCCCCC	30.01	10470851
1050	Phosphorylation	RGLTPPASYNLDDDQ CCCCCCCCCCCCCCH	21.96	28857561
1051	Phosphorylation	GLTPPASYNLDDDQA CCCCCCCCCCCCCHH	23.11	-
1066	Ubiquitination	AWENELQKMTRGQLQ HHHHHHHHHHHHHHH	55.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RB6I2_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RB6I2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RB6I2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RAB6A_HUMAN	RAB6A	physical	11929610
RAB6B_HUMAN	RAB6B	physical	11929610
NEMO_HUMAN	IKBKG	physical	20932476
IKKA_HUMAN	CHUK	physical	15218148
IKKB_HUMAN	IKBKB	physical	15218148
NEMO_HUMAN	IKBKG	physical	15218148
IKBA_HUMAN	NFKBIA	physical	15218148
A4_HUMAN	APP	physical	21832049
VA0D1_HUMAN	ATP6V0D1	physical	22939629
WDR4_HUMAN	WDR4	physical	22939629
ARHL2_HUMAN	ADPRHL2	physical	26344197
SNX2_HUMAN	SNX2	physical	26344197
OFD1_HUMAN	OFD1	physical	27173435

Drug and Disease Associations

Kegg Disease
OMIM Disease
188550	Thyroid papillary carcinoma (TPC)
Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RB6I2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-75, AND MASSSPECTROMETRY.	19690332 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-17; SER-21; SER-191 ANDTHR-1046, AND MASS SPECTROMETRY.	18669648 [Abstract]
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization."; Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; Nat. Biotechnol. 24:1285-1292(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-17 AND SER-21, AND MASSSPECTROMETRY.	16964243 [Abstract]