DYST_HUMAN - dbPTM
DYST_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DYST_HUMAN
UniProt AC Q03001
Protein Name Dystonin
Gene Name DST
Organism Homo sapiens (Human).
Sequence Length 7570
Subcellular Localization Cytoplasm, cytoskeleton . Cell projection, axon . Associates with intermediate filaments, actin and microtubule cytoskeletons. Localizes to actin stress fibers and to actin-rich ruffling at the cortex of cells (By similarity). Associated at the growi
Protein Description Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1 (By similarity).; Isoform 3: plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity.; Isoform 6: required for bundling actin filaments around the nucleus.; Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport..
Protein Sequence MAGYLSPAAYLYVEEQEYLQAYEDVLERYKDERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPREKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNAIIHKYRPDLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSLYDAFPKVPEGGEGIGANDVEVKWIEYQNMVNYLIQWIRHHVTTMSERTFPNNPVELKALYNQYLQFKETEIPPKETEKSKIKRLYKLLEIWIEFGRIKLLQGYHPNDIEKEWGKLIIAMLEREKALRPEVERLEMLQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHVIDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSKGRILTTEQTKLMISGITQSLNSGFAQTLHPSLTSGLTQSLTPSLTSSSMTSGLSSGMTSRLTPSVTPAYTPGFPSGLVPNFSSGVEPNSLQTLKLMQIRKPLLKSSLLDQNLTEEEINMKFVQDLLNWVDEMQVQLDRTEWGSDLPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNTSRNQERHLDTLHNFVSRATNELIWLNEKEEEEVAYDWSERNTNIARKKDYHAELMRELDQKEENIKSVQEIAEQLLLENHPARLTIEAYRAAMQTQWSWILQLCQCVEQHIKENTAYFEFFNDAKEATDYLRNLKDAIQRKYSCDRSSSIHKLEDLVQESMEEKEELLQYKSTIANLMGKAKTIIQLKPRNSDCPLKTSIPIKAICDYRQIEITIYKDDECVLANNSHRAKWKVISPTGNEAMVPSVCFTVPPPNKEAVDLANRIEQQYQNVLTLWHESHINMKSVVSWHYLINEIDRIRASNVASIKTMLPGEHQQVLSNLQSRFEDFLEDSQESQVFSGSDITQLEKEVNVCKQYYQELLKSAEREEQEESVYNLYISEVRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLKTVNLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYELQTMTYRAMVDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEKSLEEEKKEHVEKAKELQKWVSNISKTLKDAEKAGKPPFSKQKISSEEISTKKEQLSEALQTIQLFLAKHGDKMTDEERNELEKQVKTLQESYNLLFSESLKQLQESQTSGDVKVEEKLDKVIAGTIDQTTGEVLSVFQAVLRGLIDYDTGIRLLETQLMISGLISPELRKCFDLKDAKSHGLIDEQILCQLKELSKAKEIISAASPTTIPVLDALAQSMITESMAIKVLEILLSTGSLVIPATGEQLTLQKAFQQNLVSSALFSKVLERQNMCKDLIDPCTSEKVSLIDMVQRSTLQENTGMWLLPVRPQEGGRITLKCGRNISILRAAHEGLIDRETMFRLLSAQLLSGGLINSNSGQRMTVEEAVREGVIDRDTASSILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQRGYVGLIWPHSGEIFPTSSSLQQELITNELAYKILNGRQKIAALYIPESSQVIGLDAAKQLGIIDNNTASILKNITLPDKMPDLGDLEACKNARRWLSFCKFQPSTVHDYRQEEDVFDGEEPVTTQTSEETKKLFLSYLMINSYMDANTGQRLLLYDGDLDEAVGMLLEGCHAEFDGNTAIKECLDVLSSSGVFLNNASGREKDECTATPSSFNKCHCGEPEHEETPENRKCAIDEEFNEMRNTVINSEFSQSGKLASTISIDPKVNSSPSVCVPSLISYLTQTELADISMLRSDSENILTNYENQSRVETNERANECSHSKNIQNFPSDLIENPIMKSKMSKFCGVNETENEDNTNRDSPIFDYSPRLSALLSHDKLMHSQGSFNDTHTPESNGNKCEAPALSFSDKTMLSGQRIGEKFQDQFLGIAAINISLPGEQYGQKSLNMISSNPQVQYHNDKYISNTSGEDEKTHPGFQQMPEDKEDESEIEEYSCAVTPGGDTDNAIVSLTCATPLLDETISASDYETSLLNDQQNNTGTDTDSDDDFYDTPLFEDDDHDSLLLDGDDRDCLHPEDYDTLQEENDETASPADVFYDVSKENENSMVPQGAPVGSLSVKNKAHCLQDFLMDVEKDELDSGEKIHLNPVGSDKVNGQSLETGSERECTNILEGDESDSLTDYDIVGGKESFTASLKFDDSGSWRGRKEEYVTGQEFHSDTDHLDSMQSEESYGDYIYDSNDQDDDDDDGIDEEGGGIRDENGKPRCQNVAEDMDIQLCASILNENSDENENINTMILLDKMHSCSSLEKQQRVNVVQLASPSENNLVTEKSNLPEYTTEIAGKSKENLLNHEMVLKDVLPPIIKDTESEKTFGPASISHDNNNISSTSELGTDLANTKVKLIQGSELPELTDSVKGKDEYFKNMTPKVDSSLDHIICTEPDLIGKPAEESHLSLIASVTDKDPQGNGSDLIKGRDGKSDILIEDETSIQKMYLGEGEVLVEGLVEEENRHLKLLPGKNTRDSFKLINSQFPFPQITNNEELNQKGSLKKATVTLKDEPNNLQIIVSKSPVQFENLEEIFDTSVSKEISDDITSDITSWEGNTHFEESFTDGPEKELDLFTYLKHCAKNIKAKDVAKPNEDVPSHVLITAPPMKEHLQLGVNNTKEKSTSTQKDSPLNDMIQSNDLCSKESISGGGTEISQFTPESIEATLSILSRKHVEDVGKNDFLQSERCANGLGNDNSSNTLNTDYSFLEINNKKERIEQQLPKEQALSPRSQEKEVQIPELSQVFVEDVKDILKSRLKEGHMNPQEVEEPSACADTKILIQNLIKRITTSQLVNEASTVPSDSQMSDSSGVSPMTNSSELKPESRDDPFCIGNLKSELLLNILKQDQHSQKITGVFELMRELTHMEYDLEKRGITSKVLPLQLENIFYKLLADGYSEKIEHVGDFNQKACSTSEMMEEKPHILGDIKSKEGNYYSPNLETVKEIGLESSTVWASTLPRDEKLKDLCNDFPSHLECTSGSKEMASGDSSTEQFSSELQQCLQHTEKMHEYLTLLQDMKPPLDNQESLDNNLEALKNQLRQLETFELGLAPIAVILRKDMKLAEEFLKSLPSDFPRGHVEELSISHQSLKTAFSSLSNVSSERTKQIMLAIDSEMSKLAVSHEEFLHKLKSFSDWVSEKSKSVKDIEIVNVQDSEYVKKRLEFLKNVLKDLGHTKMQLETTAFDVQFFISEYAQDLSPNQSKQLLRLLNTTQKCFLDVQESVTTQVERLETQLHLEQDLDDQKIVAERQQEYKEKLQGICDLLTQTENRLIGHQEAFMIGDGTVELKKYQSKQEELQKDMQGSAQALAEVVKNTENFLKENGEKLSQEDKALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTKHKQVIEQNGTHFQEGDGKSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQYLSPEEKEKLQKNMKELKVHYETALAESEKKMKLTHSLQEELEKFDADYTEFEHWLQQSEQELENLEAGADDINGLMTKLKRQKSFSEDVISHKGDLRYITISGNRVLEAAKSCSKRDGGKVDTSATHREVQRKLDHATDRFRSLYSKCNVLGNNLKDLVDKYQHYEDASCGLLAGLQACEATASKHLSEPIAVDPKNLQRQLEETKALQGQISSQQVAVEKLKKTAEVLLDARGSLLPAKNDIQKTLDDIVGRYEDLSKSVNERNEKLQITLTRSLSVQDGLDEMLDWMGNVESSLKEQGQVPLNSTALQDIISKNIMLEQDIAGRQSSINAMNEKVKKFMETTDPSTASSLQAKMKDLSARFSEASHKHKETLAKMEELKTKVELFENLSEKLQTFLETKTQALTEVDVPGKDVTELSQYMQESTSEFLEHKKHLEVLHSLLKEISSHGLPSDKALVLEKTNNLSKKFKEMEDTIKEKKEAVTSCQEQLDAFQVLVKSLKSWIKETTKKVPIVQPSFGAEDLGKSLEDTKKLQEKWSLKTPEIQKVNNSGISLCNLISAVTTPAKAIAAVKSGGAVLNGEGTATNTEEFWANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKTATKWQQTPAPTDTEAVKTQVEQNKSFEAELKQNVNKVQELKDKLTELLEENPDTPEAPRWKQMLTEIDSKWQELNQLTIDRQQKLEESSNNLTQFQTVEAQLKQWLVEKELMVSVLGPLSIDPNMLNTQRQQVQILLQEFATRKPQYEQLTAAGQGILSRPGEDPSLRGIVKEQLAAVTQKWDSLTGQLSDRCDWIDQAIVKSTQYQSLLRSLSDKLSDLDNKLSSSLAVSTHPDAMNQQLETAQKMKQEIQQEKKQIKVAQALCEDLSALVKEEYLKAELSRQLEGILKSFKDVEQKAENHVQHLQSACASSHQFQQMSRDFQAWLDTKKEEQNKSHPISAKLDVLESLIKDHKDFSKTLTAQSHMYEKTIAEGENLLLKTQGSEKAALQLQLNTIKTNWDTFNKQVKERENKLKESLEKALKYKEQVETLWPWIDKCQNNLEEIKFCLDPAEGENSIAKLKSLQKEMDQHFGMVELLNNTANSLLSVCEIDKEVVTDENKSLIQKVDMVTEQLHSKKFCLENMTQKFKEFQEVSKESKRQLQCAKEQLDIHDSLGSQAYSNKYLTMLQTQQKSLQALKHQVDLAKRLAQDLVVEASDSKGTSDVLLQVETIAQEHSTLSQQVDEKCSFLETKLQGIGHFQNTIREMFSQFAEFDDELDSMAPVGRDAETLQKQKETIKAFLKKLEALMASNDNANKTCKMMLATEETSPDLVGIKRDLEALSKQCNKLLDRAQAREEQVEGTIKRLEEFYSKLKEFSILLQKAEEHEESQGPVGMETETINQQLNMFKVFQKEEIEPLQGKQQDVNWLGQGLIQSAAKSTSTQGLEHDLDDVNARWKTLNKKVAQRAAQLQEALLHCGRFQDALESLLSWMVDTEELVANQKPPSAEFKVVKAQIQEQKLLQRLLDDRKSTVEVIKREGEKIATTAEPADKVKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRLVNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKLSKLSVQDYSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVLIIQDKLEAIKARYKDITKLSTDVAKTLEQALQLARRLHSTHEELCTWLDKVEVELLSYETQVLKGEEASQAQMRPKELKKEAKNNKALLDSLNEVSSALLELVPWRAREGLEKMVAEDNERYRLVSDTITQKVEEIDAAILRSQQFDQAADAELSWITETEKKLMSLGDIRLEQDQTSAQLQVQKTFTMEILRHKDIIDDLVKSGHKIMTACSEEEKQSMKKKLDKVLKNYDTICQINSERYLQLERAQSLVNQFWETYEELWPWLTETQSIISQLPAPALEYETLRQQQEEHRQLRELIAEHKPHIDKMNKTGPQLLELSPGEGFSIQEKYVAADTLYSQIKEDVKKRAVALDEAISQSTQFHDKIDQILESLERIVERLRQPPSISAEVEKIKEQISENKNVSVDMEKLQPLYETLKQRGEEMIARSGGTDKDISAKAVQDKLDQMVFIWENIHTLVEEREAKLLDVMELAEKFWCDHMSLIVTIKDTQDFIRDLEDPGIDPSVVKQQQEAAETIREEIDGLQEELDIVINLGSELIAACGEPDKPIVKKSIDELNSAWDSLNKAWKDRIDKLEEAMQAAVQYQDGLQAVFDWVDIAGGKLASMSPIGTDLETVKQQIEELKQFKSEAYQQQIEMERLNHQAELLLKKVTEESDKHTVQDPLMELKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLSEQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLASKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAETNIDQDINNLKEKWESVETKLNERKTKLEEALNLAMEFHNSLQDFINWLTQAEQTLNVASRPSLILDTVLFQIDEHKVFANEVNSHREQIIELDKTGTHLKYFSQKQDVVLIKNLLISVQSRWEKVVQRLVERGRSLDDARKRAKQFHEAWSKLMEWLEESEKSLDSELEIANDPDKIKTQLAQHKEFQKSLGAKHSVYDTTNRTGRSLKEKTSLADDNLKLDDMLSELRDKWDTICGKSVERQNKLEEALLFSGQFTDALQALIDWLYRVEPQLAEDQPVHGDIDLVMNLIDNHKAFQKELGKRTSSVQALKRSARELIEGSRDDSSWVKVQMQELSTRWETVCALSISKQTRLEAALRQAEEFHSVVHALLEWLAEAEQTLRFHGVLPDDEDALRTLIDQHKEFMKKLEEKRAELNKATTMGDTVLAICHPDSITTIKHWITIIRARFEEVLAWAKQHQQRLASALAGLIAKQELLEALLAWLQWAETTLTDKDKEVIPQEIEEVKALIAEHQTFMEEMTRKQPDVDKVTKTYKRRAADPSSLQSHIPVLDKGRAGRKRFPASSLYPSGSQTQIETKNPRVNLLVSKWQQVWLLALERRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKDAYKPITDADKIEDEVTRQVAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITTTQPTIAKGRTNMELREKFILADGASQGMAAFRPRGRRSRPSSRGASPNRSTSVSSQAAQAASPQVPATTTPKGTPIQGSKLRLPGYLSGKGFHSGEDSGLITTAAARVRTQFADSKKTPSRPGSRAGSKAGSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPTPRAGSRPSTAKPSKIPTPQRKSPASKLDKSSKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10 (in isoform 3)Phosphorylation-10.7323927012
10 (in isoform 8)Phosphorylation-10.7323927012
10 (in isoform 9)Phosphorylation-10.7323927012
11 (in isoform 3)Phosphorylation-3.1123927012
11 (in isoform 8)Phosphorylation-3.1123927012
11 (in isoform 9)Phosphorylation-3.1123927012
13 (in isoform 3)Phosphorylation-6.3623927012
13 (in isoform 8)Phosphorylation-6.3623927012
13 (in isoform 9)Phosphorylation-6.3623927012
16 (in isoform 13)Phosphorylation-31.0025072903
17 (in isoform 12)Phosphorylation-52.03-
22 (in isoform 13)Phosphorylation-10.3325072903
29PhosphorylationYEDVLERYKDERDKV
HHHHHHHHHHHHHHH
17.2620068231
29 (in isoform 13)Phosphorylation-17.2626657352
30 (in isoform 13)Phosphorylation-60.3729116813
40PhosphorylationRDKVQKKTFTKWINQ
HHHHHHHHHHHHHHH
43.5017924679
42PhosphorylationKVQKKTFTKWINQHL
HHHHHHHHHHHHHHH
30.6017924679
57 (in isoform 11)Phosphorylation-33.0328102081
59 (in isoform 11)Phosphorylation-4.2128102081
71 (in isoform 11)Phosphorylation-30.0224706070
77 (in isoform 11)Phosphorylation-39.5430266825
102PhosphorylationNVQIALDYLKRRQVK
HHHHHHHHHHHCCCE
18.25-
106 (in isoform 11)Phosphorylation-44.0230266825
106 (in isoform 13)Phosphorylation-44.0229116813
109AcetylationYLKRRQVKLVNIRND
HHHHCCCEEEEECCC
38.0827452117
109MalonylationYLKRRQVKLVNIRND
HHHHCCCEEEEECCC
38.0826320211
110 (in isoform 11)Phosphorylation-3.6126425664
111 (in isoform 11)Phosphorylation-4.6626425664
117 (in isoform 13)Phosphorylation-49.5926657352
118 (in isoform 13)Phosphorylation-4.1626657352
120 (in isoform 13)Phosphorylation-56.0326657352
125 (in isoform 13)Phosphorylation-5.1525627689
126 (in isoform 13)Phosphorylation-25.5525627689
135 (in isoform 11)Phosphorylation-2.6825159151
140 (in isoform 11)Phosphorylation-21.5226846344
141 (in isoform 11)Phosphorylation-36.3226699800
145 (in isoform 11)Phosphorylation-22.5226699800
145 (in isoform 13)Phosphorylation-22.5222777824
149 (in isoform 13)Phosphorylation-54.1323898821
150 (in isoform 13)Phosphorylation-45.6928674419
157 (in isoform 11)Phosphorylation-4.9023403867
166PhosphorylationLWTQQATEGYAGIRC
HHHHCCCCCCCCEEC
53.9017081983
166 (in isoform 11)Phosphorylation-53.9026657352
168PhosphorylationTQQATEGYAGIRCEN
HHCCCCCCCCEECCC
8.7417081983
168 (in isoform 11)Phosphorylation-8.7423403867
170PhosphorylationQATEGYAGIRCENFT
CCCCCCCCEECCCCC
10.2117081983
170 (in isoform 11)Phosphorylation-10.2125159151
172PhosphorylationTEGYAGIRCENFTTC
CCCCCCEECCCCCEE
22.3017081983
174PhosphorylationGYAGIRCENFTTCWR
CCCCEECCCCCEEEC
45.5917081983
176PhosphorylationAGIRCENFTTCWRDG
CCEECCCCCEEECCC
2.5317081983
176 (in isoform 11)Phosphorylation-2.5323403867
184 (in isoform 13)Phosphorylation-54.9528355574
186 (in isoform 13)Phosphorylation-7.0823663014
187 (in isoform 13)Phosphorylation-40.4425159151
190 (in isoform 13)Phosphorylation-1.8122617229
195 (in isoform 11)Phosphorylation-37.3629523821
211 (in isoform 13)Phosphorylation-49.4828674419
218PhosphorylationNLEHAFYVAEKIGVI
CHHHHHHHHHHHCEE
4.47-
220PhosphorylationEHAFYVAEKIGVIRL
HHHHHHHHHHCEEEE
34.85-
236PhosphorylationDPEDVDVSSPDEKSV
CHHHCCCCCCCHHHH
31.5229255136
237PhosphorylationPEDVDVSSPDEKSVI
HHHCCCCCCCHHHHH
35.9029255136
238 (in isoform 13)Phosphorylation-46.3923898821
240 (in isoform 13)Phosphorylation-51.09-
248PhosphorylationKSVITYVSSLYDAFP
HHHHHHHHHHHHHCC
12.2928857561
249PhosphorylationSVITYVSSLYDAFPK
HHHHHHHHHHHHCCC
22.3928857561
280PhosphorylationWIEYQNMVNYLIQWI
EEEHHHHHHHHHHHH
5.81-
287UbiquitinationVNYLIQWIRHHVTTM
HHHHHHHHHHHHCCC
1.40-
328AcetylationIPPKETEKSKIKRLY
CCCHHCCHHHHHHHH
65.557692079
335PhosphorylationKSKIKRLYKLLEIWI
HHHHHHHHHHHHHHH
12.0128270605
350 (in isoform 8)Acetylation-2.93-
362UbiquitinationPNDIEKEWGKLIIAM
CCHHHHHHHHHHHHH
21.93-
397PhosphorylationANRVQRDSVICEDKL
HHHHHHCCCCCCCCH
18.64-
414PhosphorylationAGNALQSDSKRLESG
CCCHHHCCHHHHHHC
45.26-
415PhosphorylationGNALQSDSKRLESGV
CCHHHCCHHHHHHCC
25.56-
419UbiquitinationQSDSKRLESGVQFQN
HCCHHHHHHCCCCCC
49.86-
492O-linked_GlycosylationSKGRILTTEQTKLMI
CCCCCCCCHHHHHHH
23.7330379171
538UbiquitinationTSSSMTSGLSSGMTS
CCCCCCCCCCCCCCC
22.03-
575PhosphorylationSSGVEPNSLQTLKLM
CCCCCCCCHHHHHHH
32.3527251275
581UbiquitinationNSLQTLKLMQIRKPL
CCHHHHHHHHHCHHH
3.25-
653PhosphorylationRAIEEFESSLKEAKI
HHHHHHHHHHHHCCC
46.4129514088
654PhosphorylationAIEEFESSLKEAKIS
HHHHHHHHHHHCCCC
35.9429514088
661PhosphorylationSLKEAKISEIQMTAP
HHHHCCCCCCCCCCC
28.1329083192
664UbiquitinationEAKISEIQMTAPLKL
HCCCCCCCCCCCCCC
21.08-
666PhosphorylationKISEIQMTAPLKLTY
CCCCCCCCCCCCCHH
14.5629083192
672PhosphorylationMTAPLKLTYAEKLHR
CCCCCCCHHHHHHHH
21.0629083192
673PhosphorylationTAPLKLTYAEKLHRL
CCCCCCHHHHHHHHH
24.1729083192
676AcetylationLKLTYAEKLHRLESQ
CCCHHHHHHHHHHHH
41.2320167786
753PhosphorylationRELDQKEENIKSVQE
HHHHHHHHHHHHHHH
71.88-
820PhosphorylationDAKEATDYLRNLKDA
CHHHHHHHHHHHHHH
11.82-
833PhosphorylationDAIQRKYSCDRSSSI
HHHHHHHCCCCCCHH
16.7530576142
834UbiquitinationAIQRKYSCDRSSSIH
HHHHHHCCCCCCHHH
4.59-
837PhosphorylationRKYSCDRSSSIHKLE
HHHCCCCCCHHHHHH
18.3929116813
838PhosphorylationKYSCDRSSSIHKLED
HHCCCCCCHHHHHHH
33.9229116813
839PhosphorylationYSCDRSSSIHKLEDL
HCCCCCCHHHHHHHH
29.9327251275
854AcetylationVQESMEEKEELLQYK
HHHHHHHHHHHHHHH
43.09-
854UbiquitinationVQESMEEKEELLQYK
HHHHHHHHHHHHHHH
43.09-
860PhosphorylationEKEELLQYKSTIANL
HHHHHHHHHHHHHHH
13.5822210691
878AcetylationAKTIIQLKPRNSDCP
CCEEEECCCCCCCCC
26.0926051181
878MalonylationAKTIIQLKPRNSDCP
CCEEEECCCCCCCCC
26.0926320211
934UbiquitinationPTGNEAMVPSVCFTV
CCCCCCCCCEEEEEC
4.05-
992PhosphorylationEIDRIRASNVASIKT
HHHHHHHCCCCCCHH
23.2224043423
996PhosphorylationIRASNVASIKTMLPG
HHHCCCCCCHHCCCH
21.9724043423
999PhosphorylationSNVASIKTMLPGEHQ
CCCCCCHHCCCHHHH
23.4420068231
1003UbiquitinationSIKTMLPGEHQQVLS
CCHHCCCHHHHHHHH
40.85-
1010PhosphorylationGEHQQVLSNLQSRFE
HHHHHHHHHHHHHHH
36.3220068231
1014PhosphorylationQVLSNLQSRFEDFLE
HHHHHHHHHHHHHHH
41.9420068231
1039UbiquitinationSDITQLEKEVNVCKQ
CCHHHHHHHHHHHHH
75.46-
1113 (in isoform 3)Phosphorylation-56.0925072903
1114 (in isoform 3)Phosphorylation-77.3425072903
1119 (in isoform 3)Phosphorylation-5.3518669648
1120 (in isoform 3)Phosphorylation-56.2525072903
1125PhosphorylationRLKDDLGTITNKCEE
HHHHHHHHHHHHHHH
31.7420860994
1127PhosphorylationKDDLGTITNKCEEFF
HHHHHHHHHHHHHHH
28.5928270605
1135PhosphorylationNKCEEFFSQAAASSS
HHHHHHHHHHHHCCC
25.0028270605
1137 (in isoform 3)Phosphorylation-12.0921406692
1140PhosphorylationFFSQAAASSSVPTLR
HHHHHHHCCCCCCHH
20.5828270605
1141PhosphorylationFSQAAASSSVPTLRS
HHHHHHCCCCCCHHH
30.5428270605
1141 (in isoform 3)Phosphorylation-30.5421406692
1142PhosphorylationSQAAASSSVPTLRSE
HHHHHCCCCCCHHHH
29.6228270605
1145PhosphorylationAASSSVPTLRSELNV
HHCCCCCCHHHHHHH
32.4228270605
1173PhosphorylationTYIDKLKTVNLVLKN
HHHHHHHHHEEEECC
25.68-
1181PhosphorylationVNLVLKNTQAAEALV
HEEEECCHHHHHHHH
20.28-
1220PhosphorylationSTLKQWRSEVDEKRQ
HHHHHHHHHHHHHHH
38.7322985185
1246SulfoxidationAKAISDEMFKTYKER
HHHCCHHHHHHHHHC
5.1130846556
1262 (in isoform 3)Phosphorylation-40.3627251275
1324PhosphorylationQENQPENSKTLATQL
HHCCCCCHHHHHHHH
25.9217081983
1358PhosphorylationCQKYAEQYSATVKDY
HHHHHHHHCCCHHHH
7.56-
1359PhosphorylationQKYAEQYSATVKDYE
HHHHHHHCCCHHHHH
19.70-
1365PhosphorylationYSATVKDYELQTMTY
HCCCHHHHHHHHCHH
16.9028270605
1369PhosphorylationVKDYELQTMTYRAMV
HHHHHHHHCHHHHHC
24.8928270605
1371PhosphorylationDYELQTMTYRAMVDS
HHHHHHCHHHHHCCC
17.1628270605
1372PhosphorylationYELQTMTYRAMVDSQ
HHHHHCHHHHHCCCC
5.8828270605
1378PhosphorylationTYRAMVDSQQKSPVK
HHHHHCCCCCCCHHH
24.0930266825
1382PhosphorylationMVDSQQKSPVKRRRM
HCCCCCCCHHHHHHH
30.5030266825
1391PhosphorylationVKRRRMQSSADLIIQ
HHHHHHHHHHHHHHH
20.3929083192
1392PhosphorylationKRRRMQSSADLIIQE
HHHHHHHHHHHHHHH
14.6529083192
1421 (in isoform 3)Ubiquitination-18.84-
1448 (in isoform 3)Phosphorylation-62.3828258704
1449 (in isoform 3)Phosphorylation-6.6428258704
1482PhosphorylationKISSEEISTKKEQLS
CCCHHHHHCCHHHHH
37.1424043423
1483PhosphorylationISSEEISTKKEQLSE
CCHHHHHCCHHHHHH
52.3624043423
1484AcetylationSSEEISTKKEQLSEA
CHHHHHCCHHHHHHH
47.74-
14842-HydroxyisobutyrylationSSEEISTKKEQLSEA
CHHHHHCCHHHHHHH
47.74-
1484AcetylationSSEEISTKKEQLSEA
CHHHHHCCHHHHHHH
47.7422424773
1502PhosphorylationIQLFLAKHGDKMTDE
HHHHHHHHCCCCCHH
44.04-
1520PhosphorylationELEKQVKTLQESYNL
HHHHHHHHHHHHHHH
34.5126074081
1524PhosphorylationQVKTLQESYNLLFSE
HHHHHHHHHHHHHHH
13.3226074081
1525PhosphorylationVKTLQESYNLLFSES
HHHHHHHHHHHHHHH
14.7426074081
1527 (in isoform 3)Phosphorylation-3.7727794612
1530PhosphorylationESYNLLFSESLKQLQ
HHHHHHHHHHHHHHH
26.6726074081
1532PhosphorylationYNLLFSESLKQLQES
HHHHHHHHHHHHHHH
39.4026074081
1537 (in isoform 3)Phosphorylation-45.8920068231
1539PhosphorylationSLKQLQESQTSGDVK
HHHHHHHHCCCCCCC
26.2926074081
1541PhosphorylationKQLQESQTSGDVKVE
HHHHHHCCCCCCCHH
43.9126074081
1542PhosphorylationQLQESQTSGDVKVEE
HHHHHCCCCCCCHHH
25.9226074081
1554 (in isoform 3)Methylation-3.46-
1556PhosphorylationEKLDKVIAGTIDQTT
HHHHHHHEEECCCCH
16.44-
1560PhosphorylationKVIAGTIDQTTGEVL
HHHEEECCCCHHHHH
39.34-
1565 (in isoform 3)Phosphorylation-37.89-
1597 (in isoform 3)Phosphorylation-8.03-
1635PhosphorylationSKAKEIISAASPTTI
HHHHHHHHHCCCCCH
24.3628152594
1638PhosphorylationKEIISAASPTTIPVL
HHHHHHCCCCCHHHH
23.6128152594
1640PhosphorylationIISAASPTTIPVLDA
HHHHCCCCCHHHHHH
34.5628152594
1641PhosphorylationISAASPTTIPVLDAL
HHHCCCCCHHHHHHH
27.0328152594
1651PhosphorylationVLDALAQSMITESMA
HHHHHHHHCCCHHHH
13.4228152594
1654PhosphorylationALAQSMITESMAIKV
HHHHHCCCHHHHHHH
17.2328152594
1656PhosphorylationAQSMITESMAIKVLE
HHHCCCHHHHHHHHH
12.5928152594
1684PhosphorylationGEQLTLQKAFQQNLV
CCHHHHHHHHHHHHH
55.0418669648
1691 (in isoform 3)Phosphorylation-5.80-
1692PhosphorylationAFQQNLVSSALFSKV
HHHHHHHHHHHHHHH
17.0425159151
1693PhosphorylationFQQNLVSSALFSKVL
HHHHHHHHHHHHHHH
22.8525159151
1697PhosphorylationLVSSALFSKVLERQN
HHHHHHHHHHHHHCC
23.7824719451
1781 (in isoform 3)Phosphorylation-2.7322167270
1787 (in isoform 3)Phosphorylation-39.9322167270
1799PhosphorylationQRMTVEEAVREGVID
CCCCHHHHHHCCCCC
7.67-
1804MethylationEEAVREGVIDRDTAS
HHHHHCCCCCCCCCH
3.35-
1883UbiquitinationLQQELITNELAYKIL
HHHHHHHHHHHHHHH
34.98-
1906 (in isoform 3)Phosphorylation-39.8828348404
1909 (in isoform 3)Phosphorylation-20.7425106551
1925PhosphorylationIIDNNTASILKNITL
CCCCCHHHHHHCCCC
26.8124719451
1993 (in isoform 3)Phosphorylation-11.4823403867
1999 (in isoform 3)Phosphorylation-8.43-
2060PhosphorylationASGREKDECTATPSS
CCCCCCCCCCCCCCC
44.8532645325
2062PhosphorylationGREKDECTATPSSFN
CCCCCCCCCCCCCCC
31.36-
2064PhosphorylationEKDECTATPSSFNKC
CCCCCCCCCCCCCCC
12.9228674419
2069UbiquitinationTATPSSFNKCHCGEP
CCCCCCCCCCCCCCC
48.25-
2111 (in isoform 3)Phosphorylation-5.33-
2113PhosphorylationSQSGKLASTISIDPK
CCCCCCCCEEECCCC
36.3929523821
2114PhosphorylationQSGKLASTISIDPKV
CCCCCCCEEECCCCC
17.0929523821
2116PhosphorylationGKLASTISIDPKVNS
CCCCCEEECCCCCCC
22.4928857561
2149PhosphorylationADISMLRSDSENILT
CCHHHCCCCCCCCCH
41.3428857561
2151PhosphorylationISMLRSDSENILTNY
HHHCCCCCCCCCHHC
33.5128857561
2172UbiquitinationETNERANECSHSKNI
HHCHHHHHCCCCCCC
36.09-
2182UbiquitinationHSKNIQNFPSDLIEN
CCCCCCCCCHHHHCC
3.34-
2205PhosphorylationKFCGVNETENEDNTN
HCCCCCCCCCCCCCC
38.6230266825
2211PhosphorylationETENEDNTNRDSPIF
CCCCCCCCCCCCCCC
43.9126657352
2215PhosphorylationEDNTNRDSPIFDYSP
CCCCCCCCCCCCCCH
19.3630266825
2220PhosphorylationRDSPIFDYSPRLSAL
CCCCCCCCCHHHHHH
15.1530266825
2221PhosphorylationDSPIFDYSPRLSALL
CCCCCCCCHHHHHHH
12.8530266825
2221UbiquitinationDSPIFDYSPRLSALL
CCCCCCCCHHHHHHH
12.85-
2225PhosphorylationFDYSPRLSALLSHDK
CCCCHHHHHHHCCCH
20.3928674419
2229PhosphorylationPRLSALLSHDKLMHS
HHHHHHHCCCHHHHC
30.41-
2236PhosphorylationSHDKLMHSQGSFNDT
CCCHHHHCCCCCCCC
23.4422199227
2239PhosphorylationKLMHSQGSFNDTHTP
HHHHCCCCCCCCCCC
17.1526437602
2243PhosphorylationSQGSFNDTHTPESNG
CCCCCCCCCCCCCCC
28.8422199227
2245PhosphorylationGSFNDTHTPESNGNK
CCCCCCCCCCCCCCC
30.7422199227
2248PhosphorylationNDTHTPESNGNKCEA
CCCCCCCCCCCCCCC
51.7622199227
2261PhosphorylationEAPALSFSDKTMLSG
CCCCCCCCCCCCCCC
34.5222199227
2304 (in isoform 3)Phosphorylation-41.42-
2336 (in isoform 3)Phosphorylation-54.49-
2340 (in isoform 3)Phosphorylation-51.90-
2393 (in isoform 3)Phosphorylation-33.42-
2442PhosphorylationEENDETASPADVFYD
HCCCCCCCHHHEEEE
28.2128387310
2457PhosphorylationVSKENENSMVPQGAP
CCCCCCCCCCCCCCC
18.25-
2466 (in isoform 3)Phosphorylation-23.0820860994
2467PhosphorylationPQGAPVGSLSVKNKA
CCCCCCCCCCCCCHH
20.0824719451
2469PhosphorylationGAPVGSLSVKNKAHC
CCCCCCCCCCCHHHH
32.51-
2491PhosphorylationVEKDELDSGEKIHLN
HCHHCCCCCCCEECC
62.5729255136
2498 (in isoform 3)Phosphorylation-18.3024245541
2502PhosphorylationIHLNPVGSDKVNGQS
EECCCCCCCCCCCEE
34.2029514088
2512PhosphorylationVNGQSLETGSERECT
CCCEECCCCCCCCCC
51.8329255136
2514PhosphorylationGQSLETGSERECTNI
CEECCCCCCCCCCCC
40.6829255136
2527PhosphorylationNILEGDESDSLTDYD
CCCCCCCCCCCCCCE
36.9226657352
2529PhosphorylationLEGDESDSLTDYDIV
CCCCCCCCCCCCEEE
42.3123403867
2531PhosphorylationGDESDSLTDYDIVGG
CCCCCCCCCCEEECC
36.1423403867
2533PhosphorylationESDSLTDYDIVGGKE
CCCCCCCCEEECCCE
11.4423403867
2541PhosphorylationDIVGGKESFTASLKF
EEECCCEEEEEEEEE
31.2330266825
2543PhosphorylationVGGKESFTASLKFDD
ECCCEEEEEEEEECC
25.3129514088
2545PhosphorylationGKESFTASLKFDDSG
CCEEEEEEEEECCCC
29.0929514088
2551O-linked_GlycosylationASLKFDDSGSWRGRK
EEEEECCCCCCCCCC
36.2530379171
2551PhosphorylationASLKFDDSGSWRGRK
EEEEECCCCCCCCCC
36.2522199227
2553O-linked_GlycosylationLKFDDSGSWRGRKEE
EEECCCCCCCCCCEE
19.9730379171
2553PhosphorylationLKFDDSGSWRGRKEE
EEECCCCCCCCCCEE
19.9722199227
2603UbiquitinationDDDDGIDEEGGGIRD
CCCCCCCCCCCCCCC
57.53-
2635 (in isoform 3)Phosphorylation-55.4522468782
2649 (in isoform 3)Phosphorylation-4.0422468782
2654PhosphorylationILLDKMHSCSSLEKQ
HHHHHHCCCCCCCHH
16.5222985185
2656PhosphorylationLDKMHSCSSLEKQQR
HHHHCCCCCCCHHHC
40.7626437602
2657PhosphorylationDKMHSCSSLEKQQRV
HHHCCCCCCCHHHCC
44.8926437602
2671PhosphorylationVNVVQLASPSENNLV
CCEEECCCCCCCCCC
37.2430266825
2673PhosphorylationVVQLASPSENNLVTE
EEECCCCCCCCCCCC
50.9230266825
2679PhosphorylationPSENNLVTEKSNLPE
CCCCCCCCCCCCCCC
40.6422199227
2687PhosphorylationEKSNLPEYTTEIAGK
CCCCCCCHHHHHCCC
19.6120562096
2727PhosphorylationEKTFGPASISHDNNN
CCCCCCCCCCCCCCC
27.9724114839
2729PhosphorylationTFGPASISHDNNNIS
CCCCCCCCCCCCCCC
23.4624114839
2743PhosphorylationSSTSELGTDLANTKV
CCCCCCCCCCCCCCE
40.2324114839
2748PhosphorylationLGTDLANTKVKLIQG
CCCCCCCCCEEEECC
31.4424114839
2774PhosphorylationGKDEYFKNMTPKVDS
CCHHHHCCCCCCCCC
29.66-
2778PhosphorylationYFKNMTPKVDSSLDH
HHCCCCCCCCCCCCE
49.89-
2786PhosphorylationVDSSLDHIICTEPDL
CCCCCCEEEECCHHH
2.49-
2793PhosphorylationIICTEPDLIGKPAEE
EEECCHHHCCCCCHH
8.99-
2819PhosphorylationKDPQGNGSDLIKGRD
CCCCCCCCCCCCCCC
32.9921406692
2838PhosphorylationILIEDETSIQKMYLG
EEECCCCCCCEECCC
22.4529759185
2843PhosphorylationETSIQKMYLGEGEVL
CCCCCEECCCCCCEE
20.7029759185
2873PhosphorylationPGKNTRDSFKLINSQ
CCCCCHHHHHHHHCC
22.4626437602
2887PhosphorylationQFPFPQITNNEELNQ
CCCCCCCCCCHHHHC
27.0920860994
2902PhosphorylationKGSLKKATVTLKDEP
CCCCCEEEEEECCCC
23.9320068231
2904PhosphorylationSLKKATVTLKDEPNN
CCCEEEEEECCCCCC
24.6020068231
2917PhosphorylationNNLQIIVSKSPVQFE
CCEEEEEECCCCCCC
19.6029514088
2919PhosphorylationLQIIVSKSPVQFENL
EEEEEECCCCCCCCH
23.8519664994
2932PhosphorylationNLEEIFDTSVSKEIS
CHHHHHCCCCCHHHC
21.9330266825
2933PhosphorylationLEEIFDTSVSKEISD
HHHHHCCCCCHHHCC
26.6622199227
2935PhosphorylationEIFDTSVSKEISDDI
HHHCCCCCHHHCCCC
25.0822199227
2971PhosphorylationEKELDLFTYLKHCAK
HHHHHHHHHHHHHHH
34.9328152594
2972PhosphorylationKELDLFTYLKHCAKN
HHHHHHHHHHHHHHH
13.3528152594
2976PhosphorylationLFTYLKHCAKNIKAK
HHHHHHHHHHHCCHH
5.72-
2999PhosphorylationVPSHVLITAPPMKEH
CCCCEEEECCCCHHH
29.0229514088
3018PhosphorylationVNNTKEKSTSTQKDS
CCCCCCCCCCCCCCC
28.7823312004
3019PhosphorylationNNTKEKSTSTQKDSP
CCCCCCCCCCCCCCC
47.0323312004
3020PhosphorylationNTKEKSTSTQKDSPL
CCCCCCCCCCCCCCH
35.6123312004
3021PhosphorylationTKEKSTSTQKDSPLN
CCCCCCCCCCCCCHH
39.4623312004
3025PhosphorylationSTSTQKDSPLNDMIQ
CCCCCCCCCHHHHHH
38.0222199227
3062PhosphorylationESIEATLSILSRKHV
HHHHHHHHHHHHCCH
19.6824719451
3065PhosphorylationEATLSILSRKHVEDV
HHHHHHHHHCCHHHC
37.3024719451
3123PhosphorylationLPKEQALSPRSQEKE
CCHHHCCCCHHCCCC
22.6829514088
3192PhosphorylationSQLVNEASTVPSDSQ
HHHHHHHHCCCCCCC
24.6123917254
3201PhosphorylationVPSDSQMSDSSGVSP
CCCCCCCCCCCCCCC
27.0623917254
3231PhosphorylationFCIGNLKSELLLNIL
CCCCHHCHHHHHHHH
36.3228258704
3329PhosphorylationKSKEGNYYSPNLETV
CCCCCCEECCCHHHH
22.9620562096
3330PhosphorylationSKEGNYYSPNLETVK
CCCCCEECCCHHHHH
9.2822199227
3349PhosphorylationESSTVWASTLPRDEK
CCCCCCHHCCCCCHH
18.1123312004
3350PhosphorylationSSTVWASTLPRDEKL
CCCCCHHCCCCCHHH
32.7924719451
3430UbiquitinationNNLEALKNQLRQLET
HHHHHHHHHHHHHHH
47.14-
3462PhosphorylationLAEEFLKSLPSDFPR
HHHHHHHCCCCCCCC
47.8921406692
3465PhosphorylationEFLKSLPSDFPRGHV
HHHHCCCCCCCCCCH
58.1221406692
3497AcetylationSNVSSERTKQIMLAI
CCCCCHHHHHHHHHH
24.21-
3497PhosphorylationSNVSSERTKQIMLAI
CCCCCHHHHHHHHHH
24.2120068231
3506PhosphorylationQIMLAIDSEMSKLAV
HHHHHHCHHHHHHCC
29.1420068231
3509PhosphorylationLAIDSEMSKLAVSHE
HHHCHHHHHHCCCHH
22.0720068231
3521UbiquitinationSHEEFLHKLKSFSDW
CHHHHHHHHHCHHHH
60.81-
3524PhosphorylationEFLHKLKSFSDWVSE
HHHHHHHCHHHHHCH
40.1820860994
3533PhosphorylationSDWVSEKSKSVKDIE
HHHHCHHCCCCCCEE
26.55-
3547PhosphorylationEIVNVQDSEYVKKRL
EEEECCCHHHHHHHH
17.4625099161
3549PhosphorylationVNVQDSEYVKKRLEF
EECCCHHHHHHHHHH
22.8625099161
3553PhosphorylationDSEYVKKRLEFLKNV
CHHHHHHHHHHHHHH
33.46-
3562UbiquitinationEFLKNVLKDLGHTKM
HHHHHHHHHCCCCCC
46.77-
3568PhosphorylationLKDLGHTKMQLETTA
HHHCCCCCCCCCCHH
20.97-
3657O-linked_GlycosylationQGICDLLTQTENRLI
HHHHHHHHHHCCCCC
40.5230379171
3659O-linked_GlycosylationICDLLTQTENRLIGH
HHHHHHHHCCCCCCC
29.9630379171
3661UbiquitinationDLLTQTENRLIGHQE
HHHHHHCCCCCCCCC
47.66-
3682PhosphorylationGTVELKKYQSKQEEL
CCHHHHHHHHHHHHH
19.21-
3707PhosphorylationLAEVVKNTENFLKEN
HHHHHHHHHHHHHHH
26.9621060948
3712MethylationKNTENFLKENGEKLS
HHHHHHHHHHHHCCC
45.02-
3756PhosphorylationKELDKVVTTAIKEET
HHHHHHHHHHHHHHH
17.31-
3862PhosphorylationAQHEKIISQHQAVII
HHHHHHHHHHHHEEE
25.69-
3886PhosphorylationEKQGQYLSPEEKEKL
HHCCCCCCHHHHHHH
25.9028674419
3920PhosphorylationKKMKLTHSLQEELEK
HHHHHHHHHHHHHHH
26.8927067055
3968PhosphorylationTKLKRQKSFSEDVIS
HHHHHCCCCCCHHHH
26.1829255136
3970PhosphorylationLKRQKSFSEDVISHK
HHHCCCCCCHHHHCC
39.7230266825
3975PhosphorylationSFSEDVISHKGDLRY
CCCCHHHHCCCCCEE
20.9923403867
3996PhosphorylationRVLEAAKSCSKRDGG
HHHHHHHHCCCCCCC
20.9228258704
4008PhosphorylationDGGKVDTSATHREVQ
CCCCCCCCHHHHHHH
27.0628258704
4010PhosphorylationGKVDTSATHREVQRK
CCCCCCHHHHHHHHH
22.6428258704
4138PhosphorylationLDDIVGRYEDLSKSV
HHHHHHHHHHHHHHH
14.10-
4159PhosphorylationLQITLTRSLSVQDGL
EEEEEEECCCCCCCH
21.5427251275
4161PhosphorylationITLTRSLSVQDGLDE
EEEEECCCCCCCHHH
20.9827251275
4167PhosphorylationLSVQDGLDEMLDWMG
CCCCCCHHHHHHHHH
44.80-
4212PhosphorylationQDIAGRQSSINAMNE
HHCCCCHHHHHHHHH
31.6520860994
4213PhosphorylationDIAGRQSSINAMNEK
HCCCCHHHHHHHHHH
16.1217081983
4227PhosphorylationKVKKFMETTDPSTAS
HHHHHHHCCCHHHHH
25.3924275569
4284PhosphorylationKLQTFLETKTQALTE
HHHHHHHHHCCHHHC
41.35-
4286PhosphorylationQTFLETKTQALTEVD
HHHHHHHCCHHHCCC
26.88-
4325PhosphorylationKHLEVLHSLLKEISS
HHHHHHHHHHHHHHH
31.1024719451
4331UbiquitinationHSLLKEISSHGLPSD
HHHHHHHHHCCCCCC
19.85-
4383PhosphorylationAFQVLVKSLKSWIKE
HHHHHHHHHHHHHHH
33.2824719451
4386PhosphorylationVLVKSLKSWIKETTK
HHHHHHHHHHHHHHC
39.0528857561
4401PhosphorylationKVPIVQPSFGAEDLG
CCCCCCCCCCHHHHC
21.1525072903
4410PhosphorylationGAEDLGKSLEDTKKL
CHHHHCCCHHHHHHH
34.8825072903
4414PhosphorylationLGKSLEDTKKLQEKW
HCCCHHHHHHHHHHH
22.2425072903
4471PhosphorylationGEGTATNTEEFWANK
CCCCCCCHHHHHHCC
32.3224400094
4542PhosphorylationTATKWQQTPAPTDTE
HCCHHCCCCCCCCHH
13.3020068231
4560PhosphorylationTQVEQNKSFEAELKQ
HHHHHCCCHHHHHHH
35.5528674419
4589PhosphorylationLLEENPDTPEAPRWK
HHHHCCCCCCCCHHH
25.0428674419
4649PhosphorylationVEKELMVSVLGPLSI
HHHHHHHHHHCCCCC
9.5429255136
4655PhosphorylationVSVLGPLSIDPNMLN
HHHHCCCCCCCCCCC
28.2529255136
4663PhosphorylationIDPNMLNTQRQQVQI
CCCCCCCHHHHHHHH
22.5929255136
4682PhosphorylationFATRKPQYEQLTAAG
HHHCCCCHHHHHHCC
17.7319835603
4686PhosphorylationKPQYEQLTAAGQGIL
CCCHHHHHHCCCCHH
17.7319835603
4694PhosphorylationAAGQGILSRPGEDPS
HCCCCHHCCCCCCCC
34.2119835603
4701PhosphorylationSRPGEDPSLRGIVKE
CCCCCCCCHHHHHHH
42.9119835603
4738PhosphorylationIDQAIVKSTQYQSLL
HHHHHHHHHHHHHHH
15.1726074081
4739PhosphorylationDQAIVKSTQYQSLLR
HHHHHHHHHHHHHHH
26.1026074081
4741PhosphorylationAIVKSTQYQSLLRSL
HHHHHHHHHHHHHHH
10.5226074081
4743PhosphorylationVKSTQYQSLLRSLSD
HHHHHHHHHHHHHHH
25.1624719451
4747PhosphorylationQYQSLLRSLSDKLSD
HHHHHHHHHHHHHHH
31.9920873877
4749PhosphorylationQSLLRSLSDKLSDLD
HHHHHHHHHHHHHHC
33.6720873877
4753PhosphorylationRSLSDKLSDLDNKLS
HHHHHHHHHHCHHHH
41.7021406692
4756PhosphorylationSDKLSDLDNKLSSSL
HHHHHHHCHHHHHHH
56.03-
4758PhosphorylationKLSDLDNKLSSSLAV
HHHHHCHHHHHHHHH
49.79-
4760PhosphorylationSDLDNKLSSSLAVST
HHHCHHHHHHHHHHC
21.3521406692
4761PhosphorylationDLDNKLSSSLAVSTH
HHCHHHHHHHHHHCC
39.5521406692
4762PhosphorylationLDNKLSSSLAVSTHP
HCHHHHHHHHHHCCH
19.5721406692
4766PhosphorylationLSSSLAVSTHPDAMN
HHHHHHHHCCHHHHH
18.5221406692
4767PhosphorylationSSSLAVSTHPDAMNQ
HHHHHHHCCHHHHHH
30.7221406692
4778PhosphorylationAMNQQLETAQKMKQE
HHHHHHHHHHHHHHH
42.8721406692
4821PhosphorylationAELSRQLEGILKSFK
HHHHHHHHHHHHHHH
35.53-
4826PhosphorylationQLEGILKSFKDVEQK
HHHHHHHHHHHHHHH
33.8024719451
4831UbiquitinationLKSFKDVEQKAENHV
HHHHHHHHHHHHHHH
57.40-
4849MethylationQSACASSHQFQQMSR
HHHHHCHHHHHHHHH
29.94-
4856PhosphorylationHQFQQMSRDFQAWLD
HHHHHHHHHHHHHHH
43.34-
4867PhosphorylationAWLDTKKEEQNKSHP
HHHHCCHHHHCCCCC
67.39-
4868PhosphorylationWLDTKKEEQNKSHPI
HHHCCHHHHCCCCCC
69.22-
4884PhosphorylationAKLDVLESLIKDHKD
HHHHHHHHHHHHCHH
31.1021406692
4934O-linked_GlycosylationLQLNTIKTNWDTFNK
HHHHHHHHCHHHHHH
37.3830379171
4969PhosphorylationEQVETLWPWIDKCQN
HHHHHHHHHHHHHHC
22.66-
4980 (in isoform 8)Phosphorylation-55.4322210691
4988 (in isoform 8)Phosphorylation-36.7723911959
4996 (in isoform 8)Phosphorylation-55.5721712546
5002 (in isoform 8)Phosphorylation-61.3721712546
5003 (in isoform 8)Phosphorylation-34.7221712546
5004 (in isoform 8)Phosphorylation-8.5018669648
5015 (in isoform 8)Phosphorylation-57.33-
5026 (in isoform 8)Phosphorylation-52.6621712546
5041 (in isoform 8)Phosphorylation-45.0422199227
5045 (in isoform 8)Phosphorylation-4.5021815630
5050 (in isoform 8)Phosphorylation-3.9222199227
5100PhosphorylationSQAYSNKYLTMLQTQ
CHHHHHHHHHHHHHH
16.20-
5102PhosphorylationAYSNKYLTMLQTQQK
HHHHHHHHHHHHHHH
16.8528258704
5106PhosphorylationKYLTMLQTQQKSLQA
HHHHHHHHHHHHHHH
29.07-
5110PhosphorylationMLQTQQKSLQALKHQ
HHHHHHHHHHHHHHH
22.7528258704
51222-HydroxyisobutyrylationKHQVDLAKRLAQDLV
HHHHHHHHHHHHHHH
56.07-
5241PhosphorylationTCKMMLATEETSPDL
HHHHHHCCCCCCCCH
30.3220860994
5242PhosphorylationCKMMLATEETSPDLV
HHHHHCCCCCCCCHH
54.38-
5244PhosphorylationMMLATEETSPDLVGI
HHHCCCCCCCCHHCH
39.0520860994
5259PhosphorylationKRDLEALSKQCNKLL
HHHHHHHHHHHHHHH
27.9423898821
5356PhosphorylationLIQSAAKSTSTQGLE
HHHHHHHCCCCCCCC
23.9027251275
5357PhosphorylationIQSAAKSTSTQGLEH
HHHHHHCCCCCCCCC
34.7827251275
5358PhosphorylationQSAAKSTSTQGLEHD
HHHHHCCCCCCCCCC
26.3127251275
5359PhosphorylationSAAKSTSTQGLEHDL
HHHHCCCCCCCCCCH
27.0927251275
5408PhosphorylationLESLLSWMVDTEELV
HHHHHHHHCCHHHHH
1.43-
5436MalonylationKAQIQEQKLLQRLLD
HHHHHHHHHHHHHHC
50.8726320211
5447PhosphorylationRLLDDRKSTVEVIKR
HHHCCCCCHHHHHHH
38.2818452278
5461PhosphorylationREGEKIATTAEPADK
HCCCEEECCCCCHHH
29.9718781797
5470UbiquitinationAEPADKVKILKQLSL
CCCHHHHHHHHHHHC
48.3218781797
5476PhosphorylationVKILKQLSLLDSRWE
HHHHHHHHCHHHHHH
25.1322199227
5484PhosphorylationLLDSRWEALLNKAET
CHHHHHHHHHHHHHH
15.47-
5489PhosphorylationWEALLNKAETRNRQL
HHHHHHHHHHHCHHH
23.48-
5492PhosphorylationLLNKAETRNRQLEGI
HHHHHHHHCHHHHHH
28.04-
5500PhosphorylationNRQLEGISVVAQQFH
CHHHHHHHHHHHHHH
22.77-
5563PhosphorylationKHLHQAVSIGQSLKV
HHHHHHHHHHHHHHH
24.82-
5569PhosphorylationVSIGQSLKVLSSRED
HHHHHHHHHHCCCCC
46.51-
5569UbiquitinationVSIGQSLKVLSSRED
HHHHHHHHHHCCCCC
46.51-
5573PhosphorylationQSLKVLSSREDKDMV
HHHHHHCCCCCHHHH
35.2124719451
5590PhosphorylationKLDFSQVWYIEIQEK
HCCHHHEEEEEEECC
4.83-
5595PhosphorylationQVWYIEIQEKSHSRS
HEEEEEEECCCCCHH
39.00-
5599PhosphorylationIEIQEKSHSRSELLQ
EEEECCCCCHHHHHH
37.99-
5611PhosphorylationLLQQALCNAKIFGED
HHHHHHHCCCCCCCC
45.15-
5615PhosphorylationALCNAKIFGEDEVEL
HHHCCCCCCCCHHHH
9.6332645325
5618PhosphorylationNAKIFGEDEVELMNW
CCCCCCCCHHHHHHH
66.6732645325
5659PhosphorylationELRVLQEDILLRKQN
HHHHHHHHHHHHCCC
24.71-
5664PhosphorylationQEDILLRKQNVDQAL
HHHHHHHCCCHHHHH
46.31-
5667PhosphorylationILLRKQNVDQALLNG
HHHHCCCHHHHHHHH
5.52-
5681PhosphorylationGLELLKQTTGDEVLI
HHHHHHHCCCCEEEE
31.03-
5682PhosphorylationLELLKQTTGDEVLII
HHHHHHCCCCEEEEE
39.89-
5692AcetylationEVLIIQDKLEAIKAR
EEEEEHHHHHHHHHH
31.6723236377
5708PhosphorylationKDITKLSTDVAKTLE
HHHHHHCHHHHHHHH
44.95-
5744PhosphorylationKVEVELLSYETQVLK
HHHHEEEEHHCCHHC
33.2817081983
5760SulfoxidationEEASQAQMRPKELKK
HHHHHHHCCHHHHHH
9.9330846556
5778PhosphorylationNNKALLDSLNEVSSA
HCHHHHHHHHHHHHH
32.82-
5853PhosphorylationETEKKLMSLGDIRLE
HHHHHHHCCCCCEEC
39.3728348404
5873PhosphorylationAQLQVQKTFTMEILR
HHHHHHHHHHHHHHH
13.7721406692
5875PhosphorylationLQVQKTFTMEILRHK
HHHHHHHHHHHHHCC
21.0821406692
5891PhosphorylationIIDDLVKSGHKIMTA
HHHHHHHCCCHHHHC
38.3524532841
5897PhosphorylationKSGHKIMTACSEEEK
HCCCHHHHCCCHHHH
28.1622985185
5900PhosphorylationHKIMTACSEEEKQSM
CHHHHCCCHHHHHHH
45.6522985185
6019PhosphorylationGFSIQEKYVAADTLY
CCCHHHHHHHHHHHH
8.4529083192
6024PhosphorylationEKYVAADTLYSQIKE
HHHHHHHHHHHHHHH
23.9129083192
6026PhosphorylationYVAADTLYSQIKEDV
HHHHHHHHHHHHHHH
10.7129083192
6027PhosphorylationVAADTLYSQIKEDVK
HHHHHHHHHHHHHHH
28.6529083192
6073PhosphorylationERLRQPPSISAEVEK
HHHHCCCCCHHHHHH
35.5417081983
6075PhosphorylationLRQPPSISAEVEKIK
HHCCCCCHHHHHHHH
23.78-
6102PhosphorylationMEKLQPLYETLKQRG
HHHHHHHHHHHHHHH
17.3526657352
6104PhosphorylationKLQPLYETLKQRGEE
HHHHHHHHHHHHHHH
26.2126657352
6192PhosphorylationEDPGIDPSVVKQQQE
CCCCCCHHHHHHHHH
35.4828355574
6302PhosphorylationPIGTDLETVKQQIEE
CCCCCHHHHHHHHHH
40.06-
6315PhosphorylationEELKQFKSEAYQQQI
HHHHHHHHHHHHHHH
28.8424043423
6318PhosphorylationKQFKSEAYQQQIEME
HHHHHHHHHHHHHHH
11.6424043423
6473AcetylationRWQNVLEKTEQRKQQ
HHHHHHHHHHHHHHH
53.8819827451
6478UbiquitinationLEKTEQRKQQLDGAL
HHHHHHHHHHHHHHH
41.93-
6512PhosphorylationTERHLLASKPLGGLP
HHHHHHHCCCCCCCC
34.4724719451
6560PhosphorylationMLARCPKSAETNIDQ
HHHCCCCCCCCCCCH
19.2420873877
6563PhosphorylationRCPKSAETNIDQDIN
CCCCCCCCCCCHHHH
36.8720873877
6664PhosphorylationKTGTHLKYFSQKQDV
CCCCHHHHCCCCCCE
18.1518491316
6666PhosphorylationGTHLKYFSQKQDVVL
CCHHHHCCCCCCEEE
33.1218491316
6726PhosphorylationWLEESEKSLDSELEI
HHHHHHHHHHHHHHH
33.1030266825
6729PhosphorylationESEKSLDSELEIAND
HHHHHHHHHHHHCCC
49.7430266825
6757MethylationFQKSLGAKHSVYDTT
HHHHHCCCCCCCCCC
34.32-
6764PhosphorylationKHSVYDTTNRTGRSL
CCCCCCCCCCCCCCH
21.5818187866
6775PhosphorylationGRSLKEKTSLADDNL
CCCHHHHCCCCCCCC
30.0220068231
6776PhosphorylationRSLKEKTSLADDNLK
CCHHHHCCCCCCCCC
32.4020068231
6789PhosphorylationLKLDDMLSELRDKWD
CCHHHHHHHHHHHHH
28.1322817900
6868O-linked_GlycosylationQKELGKRTSSVQALK
HHHHCCCCHHHHHHH
28.9230379171
6868PhosphorylationQKELGKRTSSVQALK
HHHHCCCCHHHHHHH
28.92-
6877PhosphorylationSVQALKRSARELIEG
HHHHHHHHHHHHHHC
30.05-
6893AcetylationRDDSSWVKVQMQELS
CCCCCHHHHHHHHHH
22.0826051181
6910PhosphorylationWETVCALSISKQTRL
HHHHHHHHCCHHHHH
13.2924719451
6929PhosphorylationRQAEEFHSVVHALLE
HHHHHHHHHHHHHHH
31.0229759185
6975AcetylationFMKKLEEKRAELNKA
HHHHHHHHHHHHHHC
47.7588125
7127PhosphorylationGRKRFPASSLYPSGS
CCCCCCHHHCCCCCC
22.5529396449
7128PhosphorylationRKRFPASSLYPSGSQ
CCCCCHHHCCCCCCC
33.7529396449
7130PhosphorylationRFPASSLYPSGSQTQ
CCCHHHCCCCCCCCE
9.4129396449
7132PhosphorylationPASSLYPSGSQTQIE
CHHHCCCCCCCCEEE
37.2029396449
7134PhosphorylationSSLYPSGSQTQIETK
HHCCCCCCCCEEEEC
34.1029396449
7136PhosphorylationLYPSGSQTQIETKNP
CCCCCCCCEEEECCC
32.9629396449
7140PhosphorylationGSQTQIETKNPRVNL
CCCCEEEECCCCCEE
37.4429396449
7150PhosphorylationPRVNLLVSKWQQVWL
CCCEEHHHHHHHHHH
28.31-
7191PhosphorylationFDIWRKKYMRWMNHK
HHHHHHHHHHHHHHH
8.5727762562
7239O-linked_GlycosylationPTSRLEMSAVADIFD
CCCCCCHHHHHHHHC
15.37OGP
7239PhosphorylationPTSRLEMSAVADIFD
CCCCCCHHHHHHHHC
15.3727732954
7316PhosphorylationLGNQFGDSQQLRLVR
CCCCCCCHHHHHHHH
21.8724670416
7362O-linked_GlycosylationHGSKMLRSESNSSIT
CCCCCCCCCCCCCCC
41.2230379171
7362PhosphorylationHGSKMLRSESNSSIT
CCCCCCCCCCCCCCC
41.2226437602
7364PhosphorylationSKMLRSESNSSITTT
CCCCCCCCCCCCCCC
43.1726437602
7366PhosphorylationMLRSESNSSITTTQP
CCCCCCCCCCCCCCC
32.1827732954
7367PhosphorylationLRSESNSSITTTQPT
CCCCCCCCCCCCCCC
28.3627732954
7408PhosphorylationFRPRGRRSRPSSRGA
CCCCCCCCCCCCCCC
47.3727282143
7411PhosphorylationRGRRSRPSSRGASPN
CCCCCCCCCCCCCCC
31.4027282143
7412PhosphorylationGRRSRPSSRGASPNR
CCCCCCCCCCCCCCC
37.1030576142
7416PhosphorylationRPSSRGASPNRSTSV
CCCCCCCCCCCCCCH
26.0726329039
7420PhosphorylationRGASPNRSTSVSSQA
CCCCCCCCCCHHHHH
31.5121955146
7421PhosphorylationGASPNRSTSVSSQAA
CCCCCCCCCHHHHHH
29.8821955146
7422PhosphorylationASPNRSTSVSSQAAQ
CCCCCCCCHHHHHHH
22.6525159151
7424PhosphorylationPNRSTSVSSQAAQAA
CCCCCCHHHHHHHHC
19.2521955146
7425PhosphorylationNRSTSVSSQAAQAAS
CCCCCHHHHHHHHCC
22.9821955146
7432PhosphorylationSQAAQAASPQVPATT
HHHHHHCCCCCCCCC
20.9126055452
7438PhosphorylationASPQVPATTTPKGTP
CCCCCCCCCCCCCCC
25.7323403867
7439PhosphorylationSPQVPATTTPKGTPI
CCCCCCCCCCCCCCC
43.1123403867
7440PhosphorylationPQVPATTTPKGTPIQ
CCCCCCCCCCCCCCC
20.7423403867
7444PhosphorylationATTTPKGTPIQGSKL
CCCCCCCCCCCCCCC
24.2820068231
7449PhosphorylationKGTPIQGSKLRLPGY
CCCCCCCCCCCCCCC
16.4920068231
7456PhosphorylationSKLRLPGYLSGKGFH
CCCCCCCCCCCCCCC
8.85-
7458PhosphorylationLRLPGYLSGKGFHSG
CCCCCCCCCCCCCCC
29.9425159151
7464PhosphorylationLSGKGFHSGEDSGLI
CCCCCCCCCCCCCCC
41.4322199227
7468PhosphorylationGFHSGEDSGLITTAA
CCCCCCCCCCCHHHH
31.0628555341
7485PhosphorylationVRTQFADSKKTPSRP
HHHHHCCCCCCCCCC
32.4029214152
7488PhosphorylationQFADSKKTPSRPGSR
HHCCCCCCCCCCCCC
30.1729214152
7490PhosphorylationADSKKTPSRPGSRAG
CCCCCCCCCCCCCCC
57.2321712546
7494PhosphorylationKTPSRPGSRAGSKAG
CCCCCCCCCCCCCCC
22.9521712546
7505PhosphorylationSKAGSRASSRRGSDA
CCCCCCCCCCCCCCC
24.2227174698
7506PhosphorylationKAGSRASSRRGSDAS
CCCCCCCCCCCCCCC
25.6327174698
7510PhosphorylationRASSRRGSDASDFDI
CCCCCCCCCCCCCCH
28.3530266825
7513PhosphorylationSRRGSDASDFDISEI
CCCCCCCCCCCHHHH
43.7430266825
7518PhosphorylationDASDFDISEIQSVCS
CCCCCCHHHHHHHHC
30.4130266825
7522PhosphorylationFDISEIQSVCSDVET
CCHHHHHHHHCCCCC
30.6529632367
7525PhosphorylationSEIQSVCSDVETVPQ
HHHHHHHCCCCCCCC
42.4029632367
7529PhosphorylationSVCSDVETVPQTHRP
HHHCCCCCCCCCCCC
37.0220873877
7533PhosphorylationDVETVPQTHRPTPRA
CCCCCCCCCCCCCCC
17.4920873877
7537PhosphorylationVPQTHRPTPRAGSRP
CCCCCCCCCCCCCCC
25.9320873877
7542PhosphorylationRPTPRAGSRPSTAKP
CCCCCCCCCCCCCCC
39.7828857561
7554PhosphorylationAKPSKIPTPQRKSPA
CCCCCCCCCCCCCCH
35.2128674151
7559PhosphorylationIPTPQRKSPASKLDK
CCCCCCCCCHHHCCC
28.0821712546
7562PhosphorylationPQRKSPASKLDKSSK
CCCCCCHHHCCCCCC
36.8217287340

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DYST_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DYST_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DYST_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DCTN1_HUMANDCTN1physical
14581450
ERBIN_HUMANERBB2IPphysical
11375975
ITB4_HUMANITGB4physical
10637308
ECM29_HUMANKIAA0368physical
20682791
MARE1_HUMANMAPRE1physical
22696216
EB1A_ARATHEB1Aphysical
22696216
MAL3_SCHPOmal3physical
22696216

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
614653Neuropathy, hereditary sensory and autonomic, 6 (HSAN6)
615425Epidermolysis bullosa simplex, autosomal recessive 2 (EBSB2)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DYST_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-7432 AND THR-7440, ANDMASS SPECTROMETRY.
"Global proteomic profiling of phosphopeptides using electron transferdissociation tandem mass spectrometry.";
Molina H., Horn D.M., Tang N., Mathivanan S., Pandey A.;
Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-7562, AND MASSSPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166; SER-168; SER-172(ISOFORM 6), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1324;SER-3970; SER-7510 AND SER-7513, AND MASS SPECTROMETRY.
"Quantitative analysis of global ubiquitination in HeLa cells by massspectrometry.";
Meierhofer D., Wang X., Huang L., Kaiser P.;
J. Proteome Res. 7:4566-4576(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-5461, UBIQUITINATION[LARGE SCALE ANALYSIS] AT LYS-5470, AND MASS SPECTROMETRY.
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-6764, AND MASSSPECTROMETRY.
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-40 AND THR-42, AND MASSSPECTROMETRY.
Ubiquitylation
ReferencePubMed
"Quantitative analysis of global ubiquitination in HeLa cells by massspectrometry.";
Meierhofer D., Wang X., Huang L., Kaiser P.;
J. Proteome Res. 7:4566-4576(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-5461, UBIQUITINATION[LARGE SCALE ANALYSIS] AT LYS-5470, AND MASS SPECTROMETRY.

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