| UniProt ID | MAL3_SCHPO | |
|---|---|---|
| UniProt AC | Q10113 | |
| Protein Name | Microtubule integrity protein mal3 | |
| Gene Name | mal3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 308 | |
| Subcellular Localization | Cytoplasm, cytoskeleton . Associated with microtubules. | |
| Protein Description | May play a role in regulating the integrity of microtubules possibly by influencing their stability. Involved in an anchoring mechanism to maintain tea2 and tip1 at growing microtubule ends. Strongly stimulates the ATPase activity of tea2.. | |
| Protein Sequence | MSESRQELLAWINQVTSLGLTRIEDCGKGYAMIQIFDSIYQDIPLKKVNFECNNEYQYINNWKVLQQVFLKKGIDKVVDPERLSRCKMQDNLEFVQWAKRFWDQYYPGGDYDALARRGNRGPANTRVMNSSAGATGPSRRRQVSSGSSTPSMTKSSANNNNVSSTANTAAVLRAKQAQQQITSLETQLYEVNETMFGLERERDFYFNKLREIEILVQTHLTTSPMSMENMLERIQAILYSTEDGFELPPDQPADLTTALTDHDTNNVAEEAQMTDLKDSETQRVPSAPDFVHARLQSLEVDDDENITF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 144 | Phosphorylation | PSRRRQVSSGSSTPS CCCCCCCCCCCCCCC | 22.20 | 29996109 | |
| 145 | Phosphorylation | SRRRQVSSGSSTPSM CCCCCCCCCCCCCCC | 43.78 | 29996109 | |
| 147 | Phosphorylation | RRQVSSGSSTPSMTK CCCCCCCCCCCCCCC | 32.74 | 25720772 | |
| 148 | Phosphorylation | RQVSSGSSTPSMTKS CCCCCCCCCCCCCCC | 48.11 | 29996109 | |
| 149 | Phosphorylation | QVSSGSSTPSMTKSS CCCCCCCCCCCCCCC | 22.53 | 29996109 | |
| 151 | Phosphorylation | SSGSSTPSMTKSSAN CCCCCCCCCCCCCCC | 38.89 | 25720772 | |
| 153 | Phosphorylation | GSSTPSMTKSSANNN CCCCCCCCCCCCCCC | 31.92 | 27738172 | |
| 155 | Phosphorylation | STPSMTKSSANNNNV CCCCCCCCCCCCCCC | 26.05 | 21712547 | |
| 279 | Phosphorylation | QMTDLKDSETQRVPS HCCCCCCCCCCCCCC | 40.74 | 29996109 | |
| 286 | Phosphorylation | SETQRVPSAPDFVHA CCCCCCCCCCCCHHH | 49.96 | 21712547 | |
| 297 | Phosphorylation | FVHARLQSLEVDDDE CHHHHHHCCCCCCCC | 30.96 | 24763107 | |
| 307 | Phosphorylation | VDDDENITF------ CCCCCCCCC------ | 34.57 | 21712547 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MAL3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MAL3_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MAL3_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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