dbPTM

MAD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MAD1_SCHPO
UniProt AC	P87169
Protein Name	Spindle assembly checkpoint component mad1
Gene Name	mad1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	689
Subcellular Localization	Nucleus.
Protein Description	Central component of the spindle assembly checkpoint. Has a role in the correct positioning of the septum. Required for anchoring mad2 to the nuclear periphery..
Protein Sequence	MSSKLTVYQATTSMADSPRDPFQSRSQLPRFLATSVKKPNLKKPSVNSANETKNPKLASLEFQLENLKNDLKRKELEFEREQIELQRKLAEEHEQKNSLQLRLTLVEKQLEEQSTSYQKEIEEVRNEKEATQVKIHELLDAKWKEIAELKTQIEKNDQALSEKNHEVMVSNQALQMKDTNLTNLEKLFADSREQLETKCKELAAAEQQLQELSVHNQQLEESIKQVSSSIELEKINAEQRLQISELEKLKAAQEERIEKLSSNNRNVEILKEEKNDLESKLYRFEEYRDKVATLELENEKIQTELNSWKSLITNELPTPEAVSNKLVFLQNTNANLGERVSSLESQLSNKPANQPLGANEKDAAHITELETKLKELHEQNRRLQRQKSLATQEIDLLRENLKSYDDEEAILSEKNTDMKKLERIEGLVKLVDEYKLKLESMPVSLDVDETSDEVSLQKRRRKNEHKDAGYVTELYRKNQHLLFQVKEKTNIEAFLREQIITLESSIATLRQELAQVTEINSCRVLQHRSNPTLKYERIKAAQLEMLNAENSALKALLEDKKVDCLPIQSFKIAERKALDLKKEVAEREKRIQRLKEIFSVKSLEFREAVFSLFGYKLDFMPNGSVRVTSTYSREDNTAFIFDGESSTMKLVGNPSGPEFERLIRFWCDERKTIPGMLAALTLELLDKND

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of MAD1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MAD1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MAD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MAD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KLP6_SCHPO	klp6	genetic	18931302
MAL3_SCHPO	mal3	genetic	18931302
DAD2_SCHPO	dad2	genetic	18931302
DCC1_SCHPO	dcc1	genetic	18931302
EIF2A_SCHPO	SPBC4B4.04	genetic	18818364
PPK30_SCHPO	ppk30	genetic	18818364
CLR3_SCHPO	clr3	genetic	18818364
CTF18_SCHPO	ctf18	genetic	18818364
DSC1_SCHPO	dsc1	genetic	18818364
PP2C2_SCHPO	ptc2	genetic	18818364
FFT2_SCHPO	fft2	genetic	18818364
HIF2_SCHPO	hif2	genetic	18818364
PUS1_SCHPO	pus1	genetic	18818364
KA113_SCHPO	kap113	genetic	18818364
ERS1_SCHPO	ers1	genetic	18818364
HRR1_SCHPO	hrr1	genetic	18818364
MU154_SCHPO	mug154	genetic	18818364
URM1_SCHPO	urm1	genetic	18818364
SPP1_SCHPO	spf1	genetic	18818364
RAF1_SCHPO	raf1	genetic	18818364
AGO1_SCHPO	ago1	genetic	18818364
RNC1_SCHPO	rnc1	genetic	18818364
VPH2_SCHPO	vph2	genetic	18818364
AMY1_SCHPO	SPCC757.12	genetic	18818364
RAF2_SCHPO	raf2	genetic	18818364
MED19_SCHPO	rox3	genetic	18818364
AAKB_SCHPO	amk2	genetic	18818364
JMJ4_SCHPO	jmj4	genetic	18818364
XKS1_SCHPO	xks1	genetic	18818364
MAD2_SCHPO	mad2	physical	22281223
MAD2_SCHPO	mad2	physical	22825872
MAD2_SCHPO	mad2	physical	24161933
MAD2_SCHPO	mad2	physical	24477934

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MAD1_SCHPO

Related Literatures of Post-Translational Modification