ERS1_SCHPO - dbPTM
ERS1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERS1_SCHPO
UniProt AC O94717
Protein Name RNA-silencing factor ers1
Gene Name ers1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 956
Subcellular Localization Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body .
Protein Description Involved in RNAi-dependent heterochromatin formation and centromeric silencing. Required for the conversion of centromeric pre-small interfering RNA transcripts into small interfering RNAs, histone H3 'Lys9' methylation, and the recruitment of the RITS complex to centromeric sequences..
Protein Sequence MGKVSANNQSGFFKFYIDTALLLNAEFISSFTNCINSEYNGKVKISYSSSSQQFKVIVYEEHKREAFSLFEEIVQKLKRESTVYKKPRLDIHPFGQLHYDFTTLLNFQRYLDLGYGIEDVKIKENEDIVKSKVGKKPTSSDFYIPCLIKPKIITPFEWEGNFKQVIYSPTVYNGSFKRLFYLPDNNDLLKEFAHATNTKYKASLKDNKIVVLANNDQDINAMLEKMKHIENLVSQKVYEYPEETLVYAGKIAPCQLKFLKLKFENEILYTAMHTTSIFKSVFNILGSFYTMRLLRNKHDGDSYELVPVFAKNPSKTPPCNDNFKIFSDDIKLIGCKIFAGVSLNFSSPKPAHRFYELNKTSSNLSIPVLQKPSNFHSSSTELSDNSIHQGRRAVDPVVNQNNPSNFEEMIMNKLNKLPTIDKQILGTSSLTHFQDKTTAIEHSINKSNSKQPPRFKFQLPPRPTSNTLPLEPEEELVTRYSVSSDGNTVDEAITKQSQTFQLVNSNEFNEVNANDVHKSLRQNCAKLDFDDSKSKNLLSVECLELDKGSDCSTPKSGSLTPSIDMKFLRLQDEKMDDLGDNYYTILMSSNPVSSYGVGSLYLFQPKIVCSEKYINHEEIDNMNLKSLHRWLSRSLHVLQSFSGEIELNLEFGVILYPNISSDVSACSHGFMNIYKDLNLPRSYFADCITKSVSNIDSLLNTPVKILFGRTEYTYPLIEHEVLDSKNYFVFKGSLLFTDDKRNKTEDSTVFFSMICSSKLDQFAFYKDSKQSSTCTINFPLALWDSRLRIETKVPLNDAILTEFSKSIRFRNVNKDLLLVFGNMEDRVIIHSVTRINENSVPFNKNLLPHSLEFILKCSKVKSYDISPSSINSKEAFVCLDRSKESKPIESCFSLSIQSVYMQSQFKYNNSIRAGETAPWKLANKQFIGGAITENVSDLYTAAIIMVNQLGGIHPTI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ERS1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERS1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERS1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MST2_SCHPOmst2genetic
21289066
CAF1_SCHPOcaf1genetic
18818364
VPH2_SCHPOvph2genetic
18818364
MED19_SCHPOrox3genetic
18818364
HRR1_SCHPOhrr1genetic
18818364
DCR1_SCHPOdcr1genetic
18818364
RAF1_SCHPOraf1genetic
18818364
CID12_SCHPOcid12genetic
18818364
HRR1_SCHPOhrr1physical
22474355
SWI6_SCHPOswi6physical
22474355
SWI6_SCHPOswi6physical
22733737
CID12_SCHPOcid12physical
22733737
HRR1_SCHPOhrr1physical
22733737
RDP1_SCHPOrdp1physical
22733737
DCR1_SCHPOdcr1physical
22733737
HRR1_SCHPOhrr1genetic
22733737
DCR1_SCHPOdcr1genetic
22733737
PCR1_SCHPOpcr1genetic
22733737
YORS_SCHPOstc1physical
22733737
DDB1_SCHPOddb1genetic
22681890
MPH1L_SCHPOmph1genetic
22681890
YAS2_SCHPOcsr102genetic
22681890
CSN3_SCHPOcsn3genetic
22681890
FIN1_SCHPOfin1genetic
22681890
PFL4_SCHPOpfl4genetic
22681890
YAUE_SCHPOSPAC26A3.14cgenetic
22681890
PIMT_SCHPOpcm2genetic
22681890
YFH9_SCHPOSPAC23A1.09genetic
22681890
YEN1_SCHPOSPAC11G7.01genetic
22681890
APT_SCHPOapt1genetic
22681890
AP2M_SCHPOapm4genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
CCQ1_SCHPOccq1genetic
22681890
BYE1_SCHPOSPCC645.13genetic
22681890
YIQ4_SCHPOSPAC824.04genetic
22681890
CLR4_SCHPOclr4genetic
22681890
DCTD_SCHPOdcd1genetic
22681890
MAL3_SCHPOmal3genetic
22681890
RSC4_SCHPOrsc4genetic
22681890
CHL1_SCHPOchl1genetic
22681890
GLYD_SCHPOSPAC24C9.12cgenetic
22681890
YEG7_SCHPOSPAC26H5.07cgenetic
22681890
ERG2_SCHPOerg2genetic
22681890
FSV1_SCHPOfsv1genetic
22681890
PFD3_SCHPOpac10genetic
22681890
ZFS1_SCHPOzfs1genetic
22681890
MHF2_SCHPOmhf2genetic
22681890
FKBP4_SCHPOfkbp39genetic
22681890
RAF1_SCHPOraf1genetic
22681890
ELP1_SCHPOelp1genetic
22681890
ATP11_SCHPOatp11genetic
22681890
CLR3_SCHPOclr3genetic
22681890
MST2_SCHPOmst2genetic
22681890
YIU1_SCHPOsaf5genetic
22681890
RDP1_SCHPOrdp1genetic
22681890
ROK1_SCHPOrok1genetic
22681890
RL27A_SCHPOrpl2701genetic
22681890
H2A1_SCHPOhta1genetic
22681890
YHI5_SCHPOabo2genetic
22681890
MED1_SCHPOpmc2genetic
22681890
ASK1_SCHPOask1genetic
22681890
YQ9A_SCHPOSPCC18.10genetic
22681890
YHC3_SCHPOyap18genetic
22681890
YORS_SCHPOstc1genetic
22681890
RAP1_SCHPOrap1genetic
22681890
FFT3_SCHPOfft3genetic
22681890
POF15_SCHPOpof15genetic
22681890
YOH8_SCHPOleo1genetic
22681890
YK42_SCHPOtos4genetic
22681890
KLP6_SCHPOklp6genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
CSK1_SCHPOcsk1genetic
22681890
MKH1_SCHPOmkh1genetic
22681890
YETC_SCHPOSPAC8C9.12cgenetic
22681890
YGX1_SCHPOSPBC2G5.01genetic
22681890
ASE1_SCHPOase1genetic
22681890
CSN5_SCHPOcsn5genetic
22681890

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERS1_SCHPO

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Related Literatures of Post-Translational Modification

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