BYE1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BYE1_SCHPO
• UniProt AC: Q9Y7V2
• Protein Name: Transcription factor bye1
• Gene Name: bye1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 721
• Subcellular Localization: Nucleus .
• Protein Description: Negative regulator of transcription elongation..
• Protein Sequence: MVRKSTRRTAKASEKPPETVVRCVCKSQEDIGDTWVQCDGCDCWQHASCVGLADKDIPESYYCEVCHSRSDVSSQVQNSPNKDEEHQTADLLASNEGNEKNNEENNVVSSDSKEAITKESGAELESSEPASTNSNVGMTTRSGRQSPRTPIGSTTPKSSHSPPSTRKRRGSVGTTATHTKRSKNAPKTSPKDASNETADQEKELSLHTSIDEIQNPVRKSVAKAWVSVFEKIIEKAKLEGVQGLEDLNSTSLALQLEHIMFMVLSYTTDHSLTPNNKYREKFRALRFNLVDDKNPAFRARVLKNEISFNDLVNLSSEEMANPDLKNLAEEIRQQSTENTVIKQHLIAPRDRLLDEDKLTQQDELGIAENDDAMFPKPPGELVAPISIAEEEPTIDSKSPTLPEHNPLSEDDTSNGDKAAKRKGSFNDTKPIVNVPSIVEIDDPTILDIVEEEPLARNDSFSSPYSPAEDMAEESEFFGMKEKIWTGKVKMATVSEFHANALNLFGDVSASHLFEILSATALIEGRISVSSVLQYFHALRKTPSKEIIAVLFVPTEQNSQGFDILYDYFVKRNRYGVLHSKSNSVKDAYIIPMPSGNSVPELLDLLPKVDLPKDRNFQYFMGLFVLNKSSSRHESVERATPITTSTNGIPSTYQSASGTPTNPVHSYPSLESIINALTPSDMLLIKDVVENNPQIRANPSLAINPQFMQNAISAAQKKASKQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
70	Phosphorylation	CEVCHSRSDVSSQVQ EEECCCCCCHHHHHC	45.43	29996109
73	Phosphorylation	CHSRSDVSSQVQNSP CCCCCCHHHHHCCCC	21.75	29996109
74	Phosphorylation	HSRSDVSSQVQNSPN CCCCCHHHHHCCCCC	33.93	29996109
79	Phosphorylation	VSSQVQNSPNKDEEH HHHHHCCCCCCCHHH	16.86	28889911
88	Phosphorylation	NKDEEHQTADLLASN CCCHHHHHHHHHHHC	24.85	29996109
142	Phosphorylation	NVGMTTRSGRQSPRT CCCCCCCCCCCCCCC	35.91	25720772
146	Phosphorylation	TTRSGRQSPRTPIGS CCCCCCCCCCCCCCC	18.26	25720772
149	Phosphorylation	SGRQSPRTPIGSTTP CCCCCCCCCCCCCCC	23.73	25720772
153	Phosphorylation	SPRTPIGSTTPKSSH CCCCCCCCCCCCCCC	29.81	29996109
154	Phosphorylation	PRTPIGSTTPKSSHS CCCCCCCCCCCCCCC	41.74	25720772
155	Phosphorylation	RTPIGSTTPKSSHSP CCCCCCCCCCCCCCC	30.34	29996109
158	Phosphorylation	IGSTTPKSSHSPPST CCCCCCCCCCCCCCC	34.19	24763107
159	Phosphorylation	GSTTPKSSHSPPSTR CCCCCCCCCCCCCCC	33.83	24763107
161	Phosphorylation	TTPKSSHSPPSTRKR CCCCCCCCCCCCCCC	40.22	25720772
171	Phosphorylation	STRKRRGSVGTTATH CCCCCCCCCCCHHHC	18.63	29996109
174	Phosphorylation	KRRGSVGTTATHTKR CCCCCCCCHHHCCCC	15.88	29996109
175	Phosphorylation	RRGSVGTTATHTKRS CCCCCCCHHHCCCCC	24.51	29996109
188	Phosphorylation	RSKNAPKTSPKDASN CCCCCCCCCCCCCCC	49.56	25720772
189	Phosphorylation	SKNAPKTSPKDASNE CCCCCCCCCCCCCCC	35.76	21712547
398	Phosphorylation	EPTIDSKSPTLPEHN CCCCCCCCCCCCCCC	27.37	24763107
400	Phosphorylation	TIDSKSPTLPEHNPL CCCCCCCCCCCCCCC	63.13	29996109
408	Phosphorylation	LPEHNPLSEDDTSNG CCCCCCCCCCCCCCC	39.99	24763107
412	Phosphorylation	NPLSEDDTSNGDKAA CCCCCCCCCCCHHHH	36.09	21712547
424	Phosphorylation	KAAKRKGSFNDTKPI HHHHHCCCCCCCCCC	24.74	29996109
428	Phosphorylation	RKGSFNDTKPIVNVP HCCCCCCCCCCCCCC	39.56	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BYE1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BYE1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BYE1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YJ03_SCHPO	rhn1	genetic	22681890
NOT3_SCHPO	not3	genetic	22681890
ERS1_SCHPO	ers1	genetic	22681890
YIDH_SCHPO	SPAC227.17c	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
ASSY_SCHPO	arg12	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.