ASSY_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ASSY_SCHPO
• UniProt AC: O94354
• Protein Name: Argininosuccinate synthase
• Gene Name: arg12
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 410
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MPQEVKRCVLAYSGGLDTSCILAWLIEEGWEVICYMANVGQEEDWDAAREKALKVGAKKVYVEDLREEFINDTVIPAAQANAIYENVYLLGTSLARPIIARRQIQIAEKENCIAVSHGCTGKGNDQVRFELAYYALKPDVQVIAPWRLPVFFERFAGRKDLLEYAAAKGIPVTQTTKKPWSMDENIVHCSYEAGILEDPSMTPPKDMWKLTVDPKDAPDEVEELSIHFEKGAPTKLECKDGTFSGVVSIFYQLNAIARRNGVGRIDIVENRFSGLKSRGCYETPGLTILRTAHMDLEGLTMEREVRALRDQFVTFNLAKILYNGQFFSPCTRMLLAANNVSQEVVNGVVKLSVYKGNVTVLGRKSDTAHLYDEKLSSMDELGGFDPTWTSGFIQIESMRLRNSDEGKHWM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
225	Phosphorylation	PDEVEELSIHFEKGA CCHHHEEEEEEECCC	19.80	25720772
273	Phosphorylation	DIVENRFSGLKSRGC EEEECCCCCCHHCCC	39.72	25720772
322	Phosphorylation	FNLAKILYNGQFFSP HCHHHHHHCCCCCCH	22.26	29996109
328	Phosphorylation	LYNGQFFSPCTRMLL HHCCCCCCHHHHHHH	21.98	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ASSY_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ASSY_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ASSY_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASSY_SCHPO	arg12	physical	23695164
ASSY_SCHPO	arg12	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.