UniProt ID | CHL1_SCHPO | |
---|---|---|
UniProt AC | O14147 | |
Protein Name | ATP-dependent DNA helicase chl1 {ECO:0000250|UniProtKB:P22516} | |
Gene Name | chl1 | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 844 | |
Subcellular Localization | Cytoplasm . Nucleus . | |
Protein Description | ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).. | |
Protein Sequence | MCHSKEVKFKTNFHHPYTPYDIQLEFMRSLYSSISDGKIGIFESPTGTGKSLSLICASLTWLDEHGGVLLEDNEKSNDNKSNTSSKIPDWVLEQDLKIQKDLVKETHARLEQRLEEIRKRNQSRKNQMSNNSTTYHRETKRRNINAEASTSDNCNNSNTSVDPMDEYLVTAEYTMPSTSEQSEDLFNNGYSSKVSELLRKLSPDNEKPPIVQKIYFTSRTHSQLQQLVQEIKKLNNQTFSTPIRVVSLASRKNLCINNEVRKLRPTSALNEKCIELQGSAHKCPFLQDNTQLWDFRDEALAEIMDIEELVELGQRLKVCPYYGTREAVDSAQIVTLPYPLLLQESARNALNLTLKDNICIIDEAHNLIDAICSMHSSSISFRQVCIAETQLQQYFLRFEKRLNGNNRMHIKQLIKVVYNLKSFFLNCLETNTNSKVINVDSLLVSNGADQINLHHLSEYLNVSKLARKVDGYTKYMHSLGTQELESLNDLRSERFSNGNGYEEDPYTPVLMQLESFLLNIANPAPEGKLFYEKQTGDNPYLKYLLLDPSKHVEILTEQCRSVNLAGGTMSPIDDFITLLFSDEQSRILPFSCDHIVPPENITTILVSQGPAGVPFEFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPSFAFLQQAVKVWEMNGITNRLNAKKPLFIESKDFGDNPLDTFEHYKQSVDAGLSGMLFSVIGGRLSEGINFSDKLGRAVMVVGMPFPNSQDVEWQAKVSYVEEKAKEKGINAKQASQEFYENTCMRAVNQSIGRAIRHRDDYASIILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGPAIRQLATFFRAKKMCD | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
---|---|---|---|---|---|---|
Oops, there are no PTM records of CHL1_SCHPO !! |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CHL1_SCHPO !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CHL1_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CHL1_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
DCC1_SCHPO | dcc1 | genetic | 18931302 | |
CTF18_SCHPO | ctf18 | genetic | 18045993 | |
RAD21_SCHPO | rad21 | genetic | 18045993 | |
SWI6_SCHPO | swi6 | genetic | 18818364 | |
REB1_SCHPO | reb1 | genetic | 18818364 | |
CLR4_SCHPO | clr4 | genetic | 18818364 | |
TAS3_SCHPO | tas3 | genetic | 18818364 | |
CTF18_SCHPO | ctf18 | genetic | 18818364 | |
RIK1_SCHPO | rik1 | genetic | 18818364 | |
ERS1_SCHPO | ers1 | genetic | 18818364 | |
HRR1_SCHPO | hrr1 | genetic | 18818364 | |
DCR1_SCHPO | dcr1 | genetic | 18818364 | |
MSH6_SCHPO | msh6 | genetic | 18818364 | |
RAF1_SCHPO | raf1 | genetic | 18818364 | |
JHD1_SCHPO | epe1 | genetic | 18818364 | |
AGO1_SCHPO | ago1 | genetic | 18818364 | |
RAF2_SCHPO | raf2 | genetic | 18818364 | |
CCR4_SCHPO | ccr4 | genetic | 18818364 | |
ASF1_SCHPO | cia1 | genetic | 18818364 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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