| UniProt ID | CHL1_SCHPO | |
|---|---|---|
| UniProt AC | O14147 | |
| Protein Name | ATP-dependent DNA helicase chl1 {ECO:0000250|UniProtKB:P22516} | |
| Gene Name | chl1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 844 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity).. | |
| Protein Sequence | MCHSKEVKFKTNFHHPYTPYDIQLEFMRSLYSSISDGKIGIFESPTGTGKSLSLICASLTWLDEHGGVLLEDNEKSNDNKSNTSSKIPDWVLEQDLKIQKDLVKETHARLEQRLEEIRKRNQSRKNQMSNNSTTYHRETKRRNINAEASTSDNCNNSNTSVDPMDEYLVTAEYTMPSTSEQSEDLFNNGYSSKVSELLRKLSPDNEKPPIVQKIYFTSRTHSQLQQLVQEIKKLNNQTFSTPIRVVSLASRKNLCINNEVRKLRPTSALNEKCIELQGSAHKCPFLQDNTQLWDFRDEALAEIMDIEELVELGQRLKVCPYYGTREAVDSAQIVTLPYPLLLQESARNALNLTLKDNICIIDEAHNLIDAICSMHSSSISFRQVCIAETQLQQYFLRFEKRLNGNNRMHIKQLIKVVYNLKSFFLNCLETNTNSKVINVDSLLVSNGADQINLHHLSEYLNVSKLARKVDGYTKYMHSLGTQELESLNDLRSERFSNGNGYEEDPYTPVLMQLESFLLNIANPAPEGKLFYEKQTGDNPYLKYLLLDPSKHVEILTEQCRSVNLAGGTMSPIDDFITLLFSDEQSRILPFSCDHIVPPENITTILVSQGPAGVPFEFTHKRKDDENLLKDLGRTFQNFISIIPDGVVVFFPSFAFLQQAVKVWEMNGITNRLNAKKPLFIESKDFGDNPLDTFEHYKQSVDAGLSGMLFSVIGGRLSEGINFSDKLGRAVMVVGMPFPNSQDVEWQAKVSYVEEKAKEKGINAKQASQEFYENTCMRAVNQSIGRAIRHRDDYASIILLDSRYNRSSIQRKLPNWLSKNIHSSPNFGPAIRQLATFFRAKKMCD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of CHL1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CHL1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CHL1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CHL1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DCC1_SCHPO | dcc1 | genetic | 18931302 | |
| CTF18_SCHPO | ctf18 | genetic | 18045993 | |
| RAD21_SCHPO | rad21 | genetic | 18045993 | |
| SWI6_SCHPO | swi6 | genetic | 18818364 | |
| REB1_SCHPO | reb1 | genetic | 18818364 | |
| CLR4_SCHPO | clr4 | genetic | 18818364 | |
| TAS3_SCHPO | tas3 | genetic | 18818364 | |
| CTF18_SCHPO | ctf18 | genetic | 18818364 | |
| RIK1_SCHPO | rik1 | genetic | 18818364 | |
| ERS1_SCHPO | ers1 | genetic | 18818364 | |
| HRR1_SCHPO | hrr1 | genetic | 18818364 | |
| DCR1_SCHPO | dcr1 | genetic | 18818364 | |
| MSH6_SCHPO | msh6 | genetic | 18818364 | |
| RAF1_SCHPO | raf1 | genetic | 18818364 | |
| JHD1_SCHPO | epe1 | genetic | 18818364 | |
| AGO1_SCHPO | ago1 | genetic | 18818364 | |
| RAF2_SCHPO | raf2 | genetic | 18818364 | |
| CCR4_SCHPO | ccr4 | genetic | 18818364 | |
| ASF1_SCHPO | cia1 | genetic | 18818364 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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