| UniProt ID | CSN3_SCHPO | |
|---|---|---|
| UniProt AC | Q9UT51 | |
| Protein Name | COP9 signalosome complex subunit 3 | |
| Gene Name | csn3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 338 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.. | |
| Protein Sequence | MVANMEFQGTLPFHPLEDPETLLLKFTDFVHQHSVEQCNQLSMYIIASVNSLAEAFYGSHPEKYNIVFQSVEYAAHSPAISVMHVCYLKELLRQGQYATSLKSFNDLEVSKHIPGSILLQYCMYAAYHCLGNNDLDSAKVWYFSILYIPTTTLTSFHEEAYYSFLLLYIITTGKKFQLDSATSSNVLPLKRHMVPYEEFLDAYLKDVNTLRTVIKEHWSRFLKDNSTAFILFALEVYPMHRLKKWRKTFSSLKLEYIAKQLAISQDVAKEIIQKFDNKTNFTVANGEIFLTFNALDDVSPEMHSDLCQQLIEASKNFEASIRLKSVIYSKIMAKKLNA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of CSN3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSN3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSN3_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSN3_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| IDHP_SCHPO | idp1 | genetic | 22681890 | |
| NSE6_SCHPO | nse6 | genetic | 22681890 | |
| SKH1_SCHPO | pek1 | genetic | 22681890 | |
| LCMT1_SCHPO | ppm1 | genetic | 22681890 | |
| SWI2_SCHPO | swi2 | genetic | 22681890 | |
| YGRG_SCHPO | SPBC365.16 | genetic | 22681890 | |
| PNPP_SCHPO | pho2 | genetic | 22681890 | |
| GCN5_SCHPO | gcn5 | genetic | 22681890 | |
| YJB1_SCHPO | dbl2 | genetic | 22681890 | |
| YIV5_SCHPO | SPAC144.05 | genetic | 22681890 | |
| RAD57_SCHPO | rad57 | genetic | 22681890 | |
| TPSY_SCHPO | SPAC22F8.05 | genetic | 22681890 | |
| YME2_SCHPO | SPBC83.05 | genetic | 22681890 | |
| PMP1_SCHPO | pmp1 | genetic | 22681890 | |
| ERS1_SCHPO | ers1 | genetic | 22681890 | |
| FFT3_SCHPO | fft3 | genetic | 22681890 | |
| DAD2_SCHPO | dad2 | genetic | 22681890 | |
| MU154_SCHPO | mug154 | genetic | 22681890 | |
| MCL1_SCHPO | mcl1 | genetic | 22681890 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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