NSE6_SCHPO - dbPTM
NSE6_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NSE6_SCHPO
UniProt AC O13688
Protein Name Non-structural maintenance of chromosome element 6
Gene Name nse6
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 522
Subcellular Localization Nucleus . Chromosome .
Protein Description Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. May prevent formation of excessive Holliday junctions or assist in their resolution..
Protein Sequence MNASNNISKFPDLDNSSKLIDHILDSDDSEELDELPDISSLVPSARAQSRKQYLKNDSSNSSTYRWNIDLLSSTATIDDSVAKRRKLAVQNLLQYDSTQTFQTGDEIDELIGKSVGSNVLNVLRSNPIYDDDLRYEYCSNSKARVPDWNTLKAECLKDNDLEFNEGIIPTTFGDLLSAKLVPLDIALSICSLQFFRSLGDTTCSEWIANLEKIFYSYKSSSNNLNQIVRFIFETTADMIGIDLAKRQVPIQLERTSASENLKSNLKIKVINFLKCCGTLYRFSDDTVRFEMIQDACRILIDNQVGSFCKWQFSQFMELPISLNPDFLISNIHKVSESPRVWVTILSSLSRSCQKFRKKIAFTLFVGKQSKNDDSDFSSLCQRLDEISASCNNDYTTLLYQIRTFGYAVDEKHFKTNERLECLLEKLRKIDLTISGSTDHLLLSRCEVKDCIHRLFMVLYYLNTNSAPELERIIESDLPNNNKQKDRYFKDKTSNLSMKENKSFSAKKVKKGKKKNKRQAYKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
26PhosphorylationLIDHILDSDDSEELD
HHHHHHCCCCHHHHH		39.6121712547
29PhosphorylationHILDSDDSEELDELP
HHHCCCCHHHHHCCC		37.6521712547
39PhosphorylationLDELPDISSLVPSAR
HHCCCCHHHHHHHHH		25.6221712547
40PhosphorylationDELPDISSLVPSARA
HCCCCHHHHHHHHHH		33.4521712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NSE6_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NSE6_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NSE6_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NSE1_SCHPOnse1physical
16478984
NSE2_SCHPOnse2physical
16478984
SMC6_SCHPOsmc6physical
16478984
SMC5_SCHPOsmc5physical
17005570
SMC6_SCHPOsmc6physical
17005570
SMC5_SCHPOsmc5physical
16478984
NSE3_SCHPOnse3physical
16478984
NSE5_SCHPOnse5physical
16478984
NSE2_SCHPOnse2genetic
16478984
NSE3_SCHPOnse3genetic
16478984
MUS81_SCHPOmus81genetic
16478984
HUS2_SCHPOrqh1genetic
16478984
RAD60_SCHPOrad60genetic
16478984
RAD3_SCHPOrad3genetic
16478984
CHK1_SCHPOchk1genetic
16478984
RAD55_SCHPOrad55genetic
16478984
SWI5_SCHPOswi5genetic
16478984
UVE1_SCHPOuve1genetic
16478984
RAD13_SCHPOrad13genetic
16478984
RAD18_SCHPOrhp18genetic
16478984
MUS81_SCHPOmus81genetic
22855558
SPO11_SCHPOrec12genetic
22855558
DMC1_SCHPOdmc1genetic
22855558
NSE5_SCHPOnse5physical
23695164
YJNJ_SCHPOnts1genetic
25002536
NSE5_SCHPOnse5physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NSE6_SCHPO

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Related Literatures of Post-Translational Modification

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