| UniProt ID | RAD13_SCHPO | |
|---|---|---|
| UniProt AC | P28706 | |
| Protein Name | DNA repair protein rad13 | |
| Gene Name | rad13 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1112 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair (Probable).. | |
| Protein Sequence | MGVSGLWDILEPVKRPVKLETLVNKRLAIDASIWIYQFLKAVRDKEGNQLKSSHVVGFFRRICKLLFFGIKPVFVFDGGAPSLKRQTIQKRQARRLDREENATVTANKLLALQMRHQAMLLEENNKKATALANASVQNERQMPSSMTLDNSEIKPVLNQRKNYLKPDPYQLPEMDVSFDKLGSSYDPRIMSQDELTQYVSSFTKIEDINLFDFSNIDFDSELFQSLPDTDKYSILSAARLRSRLRMGLSSEQLSEMFPNRMDFSRFQIERLKERNDLTQRLMDFTGMNEFGPSRVVSEKNREYILVKNEGAEGGWALGVISGSTNNEPIIIDDEATKLSSNLIDEDEDEAFYDVPLPSRSHSMNPRELVAAKLKEIKENSFSENQQSDEADYNVTDDLILQLATQQSLEENKKSKELFSLSASEFDKLNSEKKTFEILSTDIPAEDSMNSLLNDEENLKLEHVGDVSNDSLAFAEKKHPENGTSIFMDALPSASREKKTNDLIDPLPFQPMDWGKSIFFEKLKKPTETFMDSKTDIPSEAPDNSKLVEDTNLHTINATVNIESDLDAAKPGIENPIISPLLPVKDDEKDLDLRELNPLEPFENMKEQADDGTVTNPLNVSSDKAMSVYLLSSENAKDTGDIKSESIDAVLPTLETSSPSLSIPTDFQKEASPNKGAAALSSKVEPEVVEKLLDEEEEEMIIRMAEEEKEYDRFVSELNQRHETEEWNQEAFEKRLKELKNQKRSEKRDADEVTQVMIKECQELLRLFGLPYIVAPQEAEAQCSKLLELKLVDGIVTDDSDVFLFGGTRVYRNMFNQNKFVELYLMDDMKREFNVNQMDLIKLAHLLGSDYTMGLSRVGPVLALEILHEFPGDTGLFEFKKWFQRLSTGHASKNDVNTPVKKRINKLVGKIILPSEFPNPLVDEAYLHPAVDDSKQSFQWGIPDLDELRQFLMATVGWSKQRTNEVLLPVIQDMHKKQFVGTQSNLTQFFEGGNTNVYAPRVAYHFKSKRLENALSSFKNQISNQSPMSEEIQADADAFGESKGSDELQSRILRRKKMMASKNSSDSDSDSEDNFLASLTPKTNSSSISIENLPRKTKLSTSLLKKPSKRRRK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 467 | Phosphorylation | LEHVGDVSNDSLAFA CEEECCCCCCCHHHH | 39.39 | 24763107 | |
| 470 | Phosphorylation | VGDVSNDSLAFAEKK ECCCCCCCHHHHHHH | 26.33 | 21712547 | |
| 578 | Phosphorylation | GIENPIISPLLPVKD CCCCCCCCCCCCCCC | 15.37 | 24763107 | |
| 620 | Phosphorylation | VTNPLNVSSDKAMSV CCCCCCCCCCCCEEE | 31.57 | 24763107 | |
| 621 | Phosphorylation | TNPLNVSSDKAMSVY CCCCCCCCCCCEEEE | 38.56 | 24763107 | |
| 626 | Phosphorylation | VSSDKAMSVYLLSSE CCCCCCEEEEEECCC | 16.69 | 24763107 | |
| 631 | Phosphorylation | AMSVYLLSSENAKDT CEEEEEECCCCCCCC | 32.77 | 24763107 | |
| 632 | Phosphorylation | MSVYLLSSENAKDTG EEEEEECCCCCCCCC | 34.54 | 24763107 | |
| 655 | Phosphorylation | AVLPTLETSSPSLSI EHHCCCCCCCCCCCC | 37.30 | 25720772 | |
| 656 | Phosphorylation | VLPTLETSSPSLSIP HHCCCCCCCCCCCCC | 30.76 | 25720772 | |
| 657 | Phosphorylation | LPTLETSSPSLSIPT HCCCCCCCCCCCCCC | 26.40 | 25720772 | |
| 659 | Phosphorylation | TLETSSPSLSIPTDF CCCCCCCCCCCCCCC | 36.37 | 25720772 | |
| 671 | Phosphorylation | TDFQKEASPNKGAAA CCCCCCCCCCCCHHH | 30.05 | 29996109 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RAD13_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RAD13_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RAD13_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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