VIPI_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VIPI_SCHPO
• UniProt AC: P87216
• Protein Name: Protein vip1
• Gene Name: vip1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 257
• Protein Sequence: MSNQVIVTNISPEVTEKQISDFFSFCGKVSNISTEKSGETQTAKIQFERPSATKTALLLQDALLGQNKIQITSEDGGAASTTDQGGAGGDQAARQEDKPRSAIISELLSRGYHLSDVTLEKSIQLDQSYGVSSKFKGILESALSGVRSVNERYHVTEKANEVDNKFAISDKLNRTSSLVSTYFHKALETAAGTSAGQKVQNAYEDGKNQLLGIHNEARRLADAKNQAEGTASPASSTPTAPAEKEPTAPTTESKTTE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	SNISTEKSGETQTAK CCCCCCCCCCEEEEE	35.31	25720772
80	Phosphorylation	SEDGGAASTTDQGGA CCCCCCCCCCCCCCC	31.16	21712547
101	Phosphorylation	RQEDKPRSAIISELL HHHCCCHHHHHHHHH	32.14	25720772
115	Phosphorylation	LSRGYHLSDVTLEKS HHCCCCCCCCCHHHE	19.40	19547744
132	Phosphorylation	LDQSYGVSSKFKGIL CCHHHCCCHHHHHHH	24.37	28889911
144	Phosphorylation	GILESALSGVRSVNE HHHHHHHHCCCCHHH	34.65	25720772
175	Phosphorylation	ISDKLNRTSSLVSTY HCHHCCCCHHHHHHH	22.92	21712547
176	Phosphorylation	SDKLNRTSSLVSTYF CHHCCCCHHHHHHHH	20.59	24763107
177	Phosphorylation	DKLNRTSSLVSTYFH HHCCCCHHHHHHHHH	31.98	28889911
180	Phosphorylation	NRTSSLVSTYFHKAL CCCHHHHHHHHHHHH	23.76	21712547
181	Phosphorylation	RTSSLVSTYFHKALE CCHHHHHHHHHHHHH	23.79	21712547
194	Phosphorylation	LETAAGTSAGQKVQN HHHHCCCCHHHHHHH	29.50	28889911
230	Phosphorylation	AKNQAEGTASPASST HHHHCCCCCCCCCCC	18.57	28889911
232	Phosphorylation	NQAEGTASPASSTPT HHCCCCCCCCCCCCC	22.34	28889911
235	Phosphorylation	EGTASPASSTPTAPA CCCCCCCCCCCCCCC	37.82	28889911
236	Phosphorylation	GTASPASSTPTAPAE CCCCCCCCCCCCCCC	40.28	29996109
237	Phosphorylation	TASPASSTPTAPAEK CCCCCCCCCCCCCCC	23.36	21712547
239	Phosphorylation	SPASSTPTAPAEKEP CCCCCCCCCCCCCCC	45.41	29996109
247	Phosphorylation	APAEKEPTAPTTESK CCCCCCCCCCCCCCC	46.49	24763107
253	Phosphorylation	PTAPTTESKTTE--- CCCCCCCCCCCC---	32.96	27738172
255	Phosphorylation	APTTESKTTE----- CCCCCCCCCC-----	45.49	27738172
256	Phosphorylation	PTTESKTTE------ CCCCCCCCC------	43.35	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VIPI_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VIPI_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VIPI_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TSN1_SCHPO	tsn1	physical	24382491
VIPI_SCHPO	vip1	physical	26771498
GDI1_SCHPO	gdi1	physical	26771498
TVP15_SCHPO	SPAC6F12.04	physical	26771498
YOP1_SCHPO	yop1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132; SER-177; THR-230;SER-232 AND SER-235, AND MASS SPECTROMETRY.
PubMed: 18257517