| UniProt ID | MPH1L_SCHPO | |
|---|---|---|
| UniProt AC | O94235 | |
| Protein Name | Serine/threonine-protein kinase mph1 | |
| Gene Name | mph1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 678 | |
| Subcellular Localization | ||
| Protein Description | Involved in the regulation of the onset of mitosis. Involved in a pathway that coordinates cell proliferation and differentiation.. | |
| Protein Sequence | MSKRNPPVTNIADLVSDSSLDEDSLSFLEELQDPELYFKNDTFSSKSSHSDGTVTGDTLRRQSSGATALERLVSHPRTKNFDLQGNGGQNSALKEVNTPAYQSMHHFEHLITPLPSTNASHSEVSLSAGVNDLNSNSEHDLLPKSVNKTPGSLSISRRRRIGRIGLGPPKRAEYTLTDPSKTSDTKNSTEADEDIEMKSREVSPASNSVAATTLKPLQLHNTPLQTSQEHPKPSFHPSQFESSFSPRVQFDHDVERRASELHSRPVTVFQEPQRSASQPYESHALSPKVAPLFDNSQATPIPKRQQDVVTVANLQFIKLGVVGKGGSSMVYRIFSPDNSRLYALKEVNFINADQTTIQGYKNEIALLRKLSGNDRIIKLYAAEVNDTLGQLNMVMECGETDLANLLMKNMKKPINLNFIRMYWEQMLEAVQVVHDQNIVHSDLKPANFLLVEGNLKLIDFGIAKAIGNDTTNIHRDSHIGTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIAAIPNEQYHIHFPEVALPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELLVHPFLNPLPSYLTPLAKKPLPVSGHTNNAHPLRLSTEISASQLSMIIERSVELSKHKRLNKELIDSMAYDCVSNLRKMPE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 63 | Phosphorylation | GDTLRRQSSGATALE HHHHHHHCCCCHHHH | 29996109 | ||
| 199 | Phosphorylation | DEDIEMKSREVSPAS HHHHHHHHCCCCCCC | 24763107 | ||
| 203 | Phosphorylation | EMKSREVSPASNSVA HHHHCCCCCCCCCCC | 24763107 | ||
| 206 | Phosphorylation | SREVSPASNSVAATT HCCCCCCCCCCCCCC | 21712547 | ||
| 208 | Phosphorylation | EVSPASNSVAATTLK CCCCCCCCCCCCCCC | 21712547 | ||
| 212 | Phosphorylation | ASNSVAATTLKPLQL CCCCCCCCCCCCCEE | 21712547 | ||
| 213 | Phosphorylation | SNSVAATTLKPLQLH CCCCCCCCCCCCEEC | 21712547 | ||
| 275 | Phosphorylation | VFQEPQRSASQPYES EECCCCCCCCCCCHH | 25720772 | ||
| 277 | Phosphorylation | QEPQRSASQPYESHA CCCCCCCCCCCHHCC | 25720772 | ||
| 282 | Phosphorylation | SASQPYESHALSPKV CCCCCCHHCCCCCCC | 25720772 | ||
| 286 | Phosphorylation | PYESHALSPKVAPLF CCHHCCCCCCCCCCC | 29996109 | ||
| 470 | Phosphorylation | AKAIGNDTTNIHRDS HHHHCCCCCCCCCCC | 21712547 | ||
| 471 | Phosphorylation | KAIGNDTTNIHRDSH HHHCCCCCCCCCCCC | 21712547 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MPH1L_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MPH1L_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MPH1L_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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