dbPTM

ALY2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ALY2_SCHPO
UniProt AC	O74798
Protein Name	Putative arrestin-related trafficking adapter C2D10.04
Gene Name	SPBC2D10.04
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	658
Subcellular Localization	Cytoplasm . Localizes at the cell tip and barrier septum.
Protein Description	May regulate endocytosis in response to extracellular stimuli..
Protein Sequence	MRGELNIPALSRFGKSISASLHHQNGSSRDDNDSNPYENRSSNSGLNRRNSVFGLPSSGLSSRLSKPSLSSINNSNNSSSNTGGNVLPNPALTPVRNMSNKPPLTWSPSSANLFGTSKVTSIIGNNVSDVVPPVIKKALASSHGGGMSLSIVLLEPVLYLAGFDLNECQIENPALLRGALVLRVAKPANIRGISLSFTGRSRTEWPEGIPVKGHDTYEDKVIISHNWKFYEPTMKDADAPQHGADVARLVGEQLPLPSSAAASLRGYSVFAPGEYTYNFDLAIPNCFPESVEAKMGWVRYFLEATVERFGTFKSNLNGRTPVQLVRTPSPASLSSSELINISRDWDERLHYELQVSGKSFRLGEVVPITFRFLLLDKVRLYKLSISVVESSEYWCRSRKFHRVDPKRRVLLAERSAKHQNTDNLFETPDEGDGLSSAVFNFNVALPTCLVKERDRLTFDTTYKYIKVRHRLKALLVLSIENTENPEKRKYFEINIETPVRILSCRCVKDSTLLPPYESSSQGDNQVLLPCPCRLATTHVEPTEVTAFTTQSVLASSAPSAGRPAAAQISRPAQLFRIPSTNPPPFDGDVCPPACNTPPPNYDELFDVLSSISIQDCETDRANDDTILNNRVRRSGTIREEAPHRSLSRTVSRSFEIPR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	SGLNRRNSVFGLPSS CCCCCCCCCCCCCCC	19.60	29996109
61	Phosphorylation	GLPSSGLSSRLSKPS CCCCCCCCCCCCCCC	19.55	25720772
62	Phosphorylation	LPSSGLSSRLSKPSL CCCCCCCCCCCCCCH	42.13	25720772
68	Phosphorylation	SSRLSKPSLSSINNS CCCCCCCCHHHCCCC	44.62	27738172
70	Phosphorylation	RLSKPSLSSINNSNN CCCCCCHHHCCCCCC	33.25	27738172
75	Phosphorylation	SLSSINNSNNSSSNT CHHHCCCCCCCCCCC	32.66	27738172
93	Phosphorylation	VLPNPALTPVRNMSN CCCCCCCCCCCCCCC	23.11	29996109
107	Phosphorylation	NKPPLTWSPSSANLF CCCCCCCCCCCCCCC	15.07	29996109
109	Phosphorylation	PPLTWSPSSANLFGT CCCCCCCCCCCCCCC	36.25	29996109
110	Phosphorylation	PLTWSPSSANLFGTS CCCCCCCCCCCCCCC	25.26	29996109
116	Phosphorylation	SSANLFGTSKVTSII CCCCCCCCCCCEEEC	20.31	29996109
117	Phosphorylation	SANLFGTSKVTSIIG CCCCCCCCCCEEECC	26.05	29996109
634	Phosphorylation	LNNRVRRSGTIREEA HHHHHHHCCCCCCCC	29.71	25720772
636	Phosphorylation	NRVRRSGTIREEAPH HHHHHCCCCCCCCCC	20.36	29996109
645	Phosphorylation	REEAPHRSLSRTVSR CCCCCCCCCCCCHHH	27.88	25720772
647	Phosphorylation	EAPHRSLSRTVSRSF CCCCCCCCCCHHHCC	27.44	25720772
649	Phosphorylation	PHRSLSRTVSRSFEI CCCCCCCCHHHCCCC	21.32	29996109
651	Phosphorylation	RSLSRTVSRSFEIPR CCCCCCHHHCCCCCC	22.92	29996109
653	Phosphorylation	LSRTVSRSFEIPR-- CCCCHHHCCCCCC--	21.52	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ALY2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ALY2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ALY2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of ALY2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ALY2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-653, AND MASSSPECTROMETRY.	18257517 [Abstract]