SKH1_SCHPO - dbPTM
SKH1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SKH1_SCHPO
UniProt AC Q9Y884
Protein Name MAP kinase kinase skh1/pek1
Gene Name skh1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 363
Subcellular Localization
Protein Description Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation..
Protein Sequence MSKKPVLNLDTSNGFSEEYISHPERNDNQGIVEITDLVFSSESKLTQRKESRDSKTFVPSFLEELDDDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKINRSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTFTGTSYYMAPERISGGSYTISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPLLPQEPGIKWSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVKAFERIHVDMEEFLRQVWSD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
234PhosphorylationVSGELVNSLAGTFTG
CCHHHHHHHCCCCCC
16.47-
238PhosphorylationLVNSLAGTFTGTSYY
HHHHHCCCCCCCEEE
16.65-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SKH1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SKH1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SKH1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPM1_SCHPOpmk1physical
10365961
MKH1_SCHPOmkh1genetic
10365961
UBP3_SCHPOubp3genetic
18818364
CAF1_SCHPOcaf1genetic
18818364
CCR4_SCHPOccr4genetic
18818364
NOT2_SCHPOnot2genetic
18818364
DCR1_SCHPOdcr1genetic
18818364
SPM1_SCHPOpmk1genetic
10591634
SPM1_SCHPOpmk1physical
10591634
MPC2_SCHPOmpc2genetic
22681890
MPH1L_SCHPOmph1genetic
22681890
AMPD_SCHPOada1genetic
22681890
IDHP_SCHPOidp1genetic
22681890
YIP5_SCHPOSPAC227.06genetic
22681890
CSN3_SCHPOcsn3genetic
22681890
YC83_SCHPOSPCC622.03cgenetic
22681890
SWI6_SCHPOswi6genetic
22681890
RAF2_SCHPOraf2genetic
22681890
ALY1_SCHPOSPBC839.02genetic
22681890
ADH4_SCHPOadh4genetic
22681890
MU122_SCHPOmug122genetic
22681890
PDX1_SCHPOsnz1genetic
22681890
NUP_SCHPOSPCC285.05genetic
22681890
ERG28_SCHPOerg28genetic
22681890
LCMT1_SCHPOppm1genetic
22681890
APT_SCHPOapt1genetic
22681890
YAC5_SCHPOcph1genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
ARP8_SCHPOarp8genetic
22681890
CLR4_SCHPOclr4genetic
22681890
YGRG_SCHPOSPBC365.16genetic
22681890
YLO2_SCHPOtma23genetic
22681890
DAD1_SCHPOdad1genetic
22681890
YC1B_SCHPOmsy1genetic
22681890
YE08_SCHPOSPAC17H9.08genetic
22681890
YGWH_SCHPOgmh4genetic
22681890
MUG80_SCHPOmug80genetic
22681890
POM1_SCHPOpom1genetic
22681890
FT105_SCHPOftp105genetic
22681890
PPR5_SCHPOppr5genetic
22681890
ERG5_SCHPOerg5genetic
22681890
MOD21_SCHPOmod21genetic
22681890
YIV5_SCHPOSPAC144.05genetic
22681890
RL43B_SCHPOrpl4302genetic
22681890
GPA2_SCHPOgpa2genetic
22681890
SKI2_SCHPOSPCC550.03cgenetic
22681890
YEEB_SCHPOSPAC19A8.11cgenetic
22681890
MUG20_SCHPOmug20genetic
22681890
YF75_SCHPOspa2genetic
22681890
RLA2_SCHPOrpp201genetic
22681890
AATM_SCHPOSPBC725.01genetic
22681890
ELP3_SCHPOelp3genetic
22681890
ROK1_SCHPOrok1genetic
22681890
YE87_SCHPOSPAC9G1.07genetic
22681890
YHI5_SCHPOabo2genetic
22681890
RL16B_SCHPOrpl1601genetic
22681890
YBAC_SCHPOrud3genetic
22681890
ERD11_SCHPOerd1genetic
22681890
NMT1_SCHPOnmt1genetic
22681890
OAZ_SCHPOspa1genetic
22681890
BU107_SCHPObun107genetic
22681890
YAM5_SCHPOmso1genetic
22681890
KPR1_SCHPOSPAC4A8.14genetic
22681890
MPC1_SCHPOmpc1genetic
22681890
EMC1_SCHPOemc1genetic
22681890
YOM1_SCHPOSPBPB7E8.01genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
MUG82_SCHPOpth4genetic
22681890
RAX1_SCHPOSPAC23G3.05cgenetic
22681890
TSC1_SCHPOtsc1genetic
22681890
YIW2_SCHPOSPAC694.02genetic
22681890
YI43_SCHPOSPBC1348.03genetic
22681890
TCG1_SCHPOtcg1genetic
22681890
ULP1_SCHPOulp1genetic
22681890
CND2_SCHPOcnd2physical
26771498
PMP1_SCHPOpmp1genetic
27451356

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SKH1_SCHPO

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Related Literatures of Post-Translational Modification

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