| UniProt ID | POM1_SCHPO | |
|---|---|---|
| UniProt AC | Q09690 | |
| Protein Name | DYRK-family kinase pom1 | |
| Gene Name | pom1 {ECO:0000303|PubMed:9573052} | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1087 | |
| Subcellular Localization |
Cell tip . Cell septum . Cell membrane Peripheral membrane protein . Forms an intracellular gradient that serves to measure cell length and control mitotic entry (PubMed:19474792, PubMed:19474789, PubMed:21703453, PubMed:22342545, PubMed:26150232). |
|
| Protein Description | Polarity factor involved in localization of polarized growth and cytokinesis. [PubMed: 11230130] | |
| Protein Sequence | MGYLQSQKAVSLGDENTDALFKLHTSNRKSANMFGIKSELLNPSELSAVGSYSNDICPNRQSSSSTAADTSPSTNASNTNISFPEQEHKDELFMNVEPKGVGSSMDNHAITIHHSTGNGLLRSSFDHDYRQKNSPRNSIHRLSNISIGNNPIDFESSQQNNPSSLNTSSHHRTSSISNSKSFGTSLSYYNRSSKPSDWNQQNNGGHLSGVISITQDVSSVPLQSSVFSSGNHAYHASMAPKRSGSWRHTNFHSTSHPRAASIGNKSGIPPVPTIPPNIGHSTDHQHPKANISGSLTKSSSESKNLSTIQSPLKTSNSFFKELSPHSQITLSNVKNNHSHVGSQTKSHSFATPSVFDNNKPVSSDNHNNTTTSSQVHPDSRNPDPKAAPKAVSQKTNVDGHRNHEAKHGNTVQNESKSQKSSNKEGRSSRGGFFSRLSFSRSSSRMKKGSKAKHEDAPDVPAIPHAYIADSSTKSSYRNGKKTPTRTKSRMQQFINWFKPSKERSSNGNSDSASPPPVPRLSITRSQVSREPEKPEEIPSVPPLPSNFKDKGHVPQQRSVSYTPKRSSDTSESLQPSLSFASSNVLSEPFDRKVADLAMKAINSKRINKLLDDAKVMQSLLDRACIITPVRNTEVQLINTAPLTEYEQDEINNYDNIYFTGLRNVDKRRSADENTSSNFGFDDERGDYKVVLGDHIAYRYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVATELLGKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSSCFEGECVYTYIQSRFYRSPEVILGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACIMEIFGPPDHSLIDKCSRKKVFFDSSGKPRPFVSSKGVSRRPFSKSLHQVLQCKDVSFLSFISDCLKWDPDERMTPQQAAQHDFLTGKQDVRRPNTAPARQKFARPPNIETAPIPRPLPNLPMEYNDHTLPSPKEPSNQASNLVRSSDKFPNLLTNLDYSIISDNGFLRKPVEKSRP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 11 | Phosphorylation | LQSQKAVSLGDENTD CCCCCCEECCCCCHH | 31.34 | 21712547 | |
| 30 | Phosphorylation | LHTSNRKSANMFGIK HHCCCCCCCCCCCCC | 22.95 | 25720772 | |
| 123 | Phosphorylation | TGNGLLRSSFDHDYR CCCCHHCHHCCCCHH | 35.01 | 29996109 | |
| 124 | Phosphorylation | GNGLLRSSFDHDYRQ CCCHHCHHCCCCHHH | 28.41 | 29996109 | |
| 134 | Phosphorylation | HDYRQKNSPRNSIHR CCHHHCCCCCCHHHH | 32.07 | 29996109 | |
| 138 | Phosphorylation | QKNSPRNSIHRLSNI HCCCCCCHHHHHHCC | 22.50 | 29996109 | |
| 143 | Phosphorylation | RNSIHRLSNISIGNN CCHHHHHHCCCCCCC | 31.88 | 29996109 | |
| 146 | Phosphorylation | IHRLSNISIGNNPID HHHHHCCCCCCCCCC | 28.79 | 25720772 | |
| 294 | Phosphorylation | PKANISGSLTKSSSE CCCCCCCCCCCCCCC | 26.52 | 27738172 | |
| 298 | Phosphorylation | ISGSLTKSSSESKNL CCCCCCCCCCCCCCH | 33.58 | 27738172 | |
| 300 | Phosphorylation | GSLTKSSSESKNLST CCCCCCCCCCCCHHH | 53.64 | 25720772 | |
| 307 | Phosphorylation | SESKNLSTIQSPLKT CCCCCHHHCCCCCCC | 26.63 | 29996109 | |
| 310 | Phosphorylation | KNLSTIQSPLKTSNS CCHHHCCCCCCCCCH | 28.48 | 29996109 | |
| 314 | Phosphorylation | TIQSPLKTSNSFFKE HCCCCCCCCCHHHHH | 40.60 | 25720772 | |
| 317 | Phosphorylation | SPLKTSNSFFKELSP CCCCCCCHHHHHCCC | 31.65 | 25720772 | |
| 342 | Phosphorylation | NNHSHVGSQTKSHSF CCCCCCCCCCCCCCC | 33.32 | 21712547 | |
| 344 | Phosphorylation | HSHVGSQTKSHSFAT CCCCCCCCCCCCCCC | 35.89 | 24763107 | |
| 428 | Phosphorylation | SNKEGRSSRGGFFSR CCCCCCCCCCCHHHH | 33.32 | 25720772 | |
| 434 | Phosphorylation | SSRGGFFSRLSFSRS CCCCCHHHHHCCCCC | 30.01 | 25720772 | |
| 437 | Phosphorylation | GGFFSRLSFSRSSSR CCHHHHHCCCCCCCC | 21.77 | 25720772 | |
| 439 | Phosphorylation | FFSRLSFSRSSSRMK HHHHHCCCCCCCCCC | 28.07 | 25720772 | |
| 488 | Phosphorylation | KTPTRTKSRMQQFIN CCCCCCHHHHHHHHH | 32.16 | 24763107 | |
| 504 | Phosphorylation | FKPSKERSSNGNSDS HCCCCCCCCCCCCCC | 29.28 | 29996109 | |
| 505 | Phosphorylation | KPSKERSSNGNSDSA CCCCCCCCCCCCCCC | 55.78 | 29996109 | |
| 509 | Phosphorylation | ERSSNGNSDSASPPP CCCCCCCCCCCCCCC | 34.05 | 25720772 | |
| 511 | Phosphorylation | SSNGNSDSASPPPVP CCCCCCCCCCCCCCC | 30.39 | 29996109 | |
| 513 | Phosphorylation | NGNSDSASPPPVPRL CCCCCCCCCCCCCCE | 41.72 | 28889911 | |
| 521 | Phosphorylation | PPPVPRLSITRSQVS CCCCCCEEECHHHHC | 24.16 | 25720772 | |
| 523 | Phosphorylation | PVPRLSITRSQVSRE CCCCEEECHHHHCCC | 22.38 | 25720772 | |
| 525 | Phosphorylation | PRLSITRSQVSREPE CCEEECHHHHCCCCC | 26.70 | 29996109 | |
| 528 | Phosphorylation | SITRSQVSREPEKPE EECHHHHCCCCCCCC | 24.24 | 25720772 | |
| 558 | Phosphorylation | GHVPQQRSVSYTPKR CCCCCCCCEEECCCC | 15.86 | 21712547 | |
| 560 | Phosphorylation | VPQQRSVSYTPKRSS CCCCCCEEECCCCCC | 25.24 | 29996109 | |
| 562 | Phosphorylation | QQRSVSYTPKRSSDT CCCCEEECCCCCCCC | 18.15 | 24763107 | |
| 566 | Phosphorylation | VSYTPKRSSDTSESL EEECCCCCCCCCCCC | 38.40 | 25720772 | |
| 567 | Phosphorylation | SYTPKRSSDTSESLQ EECCCCCCCCCCCCC | 49.28 | 25720772 | |
| 569 | Phosphorylation | TPKRSSDTSESLQPS CCCCCCCCCCCCCCH | 36.02 | 21712547 | |
| 570 | Phosphorylation | PKRSSDTSESLQPSL CCCCCCCCCCCCCHH | 30.13 | 21712547 | |
| 576 | Phosphorylation | TSESLQPSLSFASSN CCCCCCCHHHHHCCC | 24.55 | 25720772 | |
| 578 | Phosphorylation | ESLQPSLSFASSNVL CCCCCHHHHHCCCCC | 24.09 | 25720772 | |
| 581 | Phosphorylation | QPSLSFASSNVLSEP CCHHHHHCCCCCCCC | 22.04 | 25720772 | |
| 669 | Phosphorylation | RNVDKRRSADENTSS CCCCCCCCCCCCCCC | 44.07 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of POM1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of POM1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of POM1_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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