PPK2_SCHPO - dbPTM
PPK2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PPK2_SCHPO
UniProt AC Q10447
Protein Name Protein kinase domain-containing protein ppk2
Gene Name ppk2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 665
Subcellular Localization Cytoplasm . Located at the cell tip.
Protein Description
Protein Sequence MLSNSTFHEHHAKSHFHNNACQSNASSSACRASEDHLVSSFPNDSIIDLQPSRPAPEPPKKKFGYYARRLSGHFLSLIHGSGNSTRSPPFHLQNQKSNGQSEVWHSSDDSGSPKRLNRSRSSKEDMYRRRSLHGLPSLSRRNSKKSSTLSRSISLHLRSESAPISLPIHLYKSYSYNHSPSSLPTVLNSQALSSPPVPTTPDEVSTNRLSSSTSSMNCRNLVPDNFNISIRPNTTNYRSSIQENSNGNRDSISPSAYDAPLLHNVDTQSIDGFVSVASHFSSASTAESLDDGHSATTIQQGDVSSYPLSRSVSTPVPMSPISISPAKPSPQSPKLSQSAVGHPSSSIPAAAMHKVSYSDDLMRFVAREKYYLQIVDCLCTQKDPLFFYTDFTKICQQDTVGTYVARQTLDKEVVVIKRFDISAVTHRRLLLEELQRLSGLSHKNLIRYNESFWYLNNIWSVFEYKDPSTKLSALIPKYFFSELNIASICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIERQTNRGAVSHVPDWLIEKNYKEGFMKDVKSLGLVALEIFQGQPNFFRKSIQSIQLTPNANVLVNRVRGLISQEFKEFLLQTLQAETLQGPNINMLLETSSFLEKRQTLNFEICLNNLNLRERKASRYSYL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
106PhosphorylationGQSEVWHSSDDSGSP
CCCCCEECCCCCCCC		21.5424763107
110PhosphorylationVWHSSDDSGSPKRLN
CEECCCCCCCCCCCC		46.2721712547
112PhosphorylationHSSDDSGSPKRLNRS
ECCCCCCCCCCCCCC		31.0621712547
131PhosphorylationEDMYRRRSLHGLPSL
HHHHHHHHHCCCCCC		23.9429996109
137PhosphorylationRSLHGLPSLSRRNSK
HHHCCCCCCCCCCCC		43.9825720772
139PhosphorylationLHGLPSLSRRNSKKS
HCCCCCCCCCCCCCC		33.2725720772
152PhosphorylationKSSTLSRSISLHLRS
CCCCCHHHEEEEECC		17.1025720772
154PhosphorylationSTLSRSISLHLRSES
CCCHHHEEEEECCCC		15.8128889911
159PhosphorylationSISLHLRSESAPISL
HEEEEECCCCCCCCC		42.1125720772
161PhosphorylationSLHLRSESAPISLPI
EEEECCCCCCCCCCE		40.3625720772
165PhosphorylationRSESAPISLPIHLYK
CCCCCCCCCCEEEEE		27.3425720772
311PhosphorylationSSYPLSRSVSTPVPM
CCCCCCCCCCCCCCC		19.6225720772
319PhosphorylationVSTPVPMSPISISPA
CCCCCCCCCCCCCCC		17.0125720772
324PhosphorylationPMSPISISPAKPSPQ
CCCCCCCCCCCCCCC		16.4125720772
357PhosphorylationAAMHKVSYSDDLMRF
HHHCCCCCCHHHHHH		21.0725720772
358PhosphorylationAMHKVSYSDDLMRFV
HHCCCCCCHHHHHHH		19.6928889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PPK2_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PPK2_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PPK2_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
UBP6_SCHPOubp6genetic
19547744
SPM1_SCHPOpmk1genetic
19547744
ILVB_SCHPOilv1genetic
22681890
ALY1_SCHPOSPBC839.02genetic
22681890
MEX67_SCHPOmex67genetic
22681890
PPR2_SCHPOppr2genetic
22681890
POM1_SCHPOpom1genetic
22681890
PPR8_SCHPOppr8genetic
22681890
SKI2_SCHPOSPCC550.03cgenetic
22681890
YEEB_SCHPOSPAC19A8.11cgenetic
22681890
NDH1_SCHPOnde2genetic
22681890
VPS72_SCHPOswc2genetic
22681890
RAF1_SCHPOraf1genetic
22681890
YQ9H_SCHPOSPCC18.17cgenetic
22681890
CTK3_SCHPOlsg1genetic
22681890
TRM82_SCHPOSPCC18.13genetic
22681890
BTB1_SCHPObtb1genetic
22681890
FFT3_SCHPOfft3genetic
22681890
MID1_SCHPOmid1genetic
22681890
RL21B_SCHPOrpl2102genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
ASSY_SCHPOarg12genetic
22681890
SKB1_SCHPOskb1physical
23615447
TEA3_SCHPOtea3physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PPK2_SCHPO

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-358, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory