SKB1_SCHPO - dbPTM
SKB1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SKB1_SCHPO
UniProt AC P78963
Protein Name Protein arginine N-methyltransferase skb1 {ECO:0000303|PubMed:11278267}
Gene Name skb1 {ECO:0000303|PubMed:8943016}
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 645
Subcellular Localization Nucleus . Localizes to cell ends, sites of septation, and nuclei.
Protein Description S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that can catalyze both the mono- and symmetric (type II) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity). Positively modulates the shk1 kinase function. May be a mediator of hyperosmotic stress response. [PubMed: 11278267]
Protein Sequence MLLRDGRIPQYSIYPLPVPPMNSKTPTLGIVCSEGTISLSLEEGFEFVGVPLSGEGLKLRVEALAPSERLQEFLDDEVAYHPEENVHKVVGLSSAWLELDSEDTLIADRSEEVLLKEASYASYCGLSSIILNGPTSPMNVMRYARAVSSALNSTMNLKFLVQLAIESGHEDYFETWKMWDTIRSACGYHPRLKVALELPPACSPPIELVNRWYAEPIEMITMSCMAFVPNPNGYPVLGRKLRAIYALYLRLNPRILLWDNDAPEKIGDSPDYSIYMKHLFDSQPPAPLVEDLADSYKDYLQVPLQPLSYNLENITYEIFERDPVKYAQYEQAIFSALMDRDESSVTRIAVVGAGRGPLVDCALRAAISSSRTVDMIALEKNPNAFSMLLMRNRQDWAGKVTLVFGDMRTWNPDYKIDILVSELLGSMGDNELSPECLDGVQHVLDEETGICIPSSYISYVTPIMSPKLWSEARNMNDPNAFERQYVVLMNSFDFLAADDEFRFQSLWSFHHPNKDSEVYTKNLHNKRFASVRFQASSPGILHGFAGYFEATLYKDISLSIMPATMEAKSPDMFSWFPIYMPIKKPMYVPENSQLEFHMWRLTDGMRVWFEWCANAYLVLRNGSQIKLSSTEVHNISGKAFSCNMY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of SKB1_SCHPO !!
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SKB1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SKB1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SKB1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ORB6_SCHPOorb6physical
12646585
SHK2_SCHPOshk2physical
9660817
SKB1_SCHPOskb1physical
9660817
CDK1_SCHPOcdc2physical
9843966
DDB1_SCHPOddb1genetic
22681890
YGDH_SCHPOSPBC1773.17cgenetic
22681890
YE0C_SCHPOSPAC17H9.12cgenetic
22681890
DAD1_SCHPOdad1genetic
22681890
ATP11_SCHPOatp11genetic
22681890
MID1_SCHPOmid1genetic
22681890
RL19B_SCHPOrpl1902genetic
22681890
CDR1_SCHPOcdr1physical
23615447
WEE1_SCHPOwee1physical
23615447
ORB6_SCHPOorb6physical
23615447
SKB1_SCHPOskb1physical
23615447
WEE1_SCHPOwee1genetic
23615447
STE20_SCHPOshk1physical
23615447
PPK2_SCHPOtea5physical
23615447
PPK5_SCHPOpom2physical
23615447
YFR3_SCHPOslf1physical
25009287
G3P1_SCHPOtdh1physical
25009287
YE04_SCHPOSPAC17H9.04cphysical
25009287
EIF3C_SCHPOtif33physical
25009287
TRPG_SCHPOtrp1physical
25009287
CDC48_SCHPOcdc48physical
25009287
RPA2_SCHPOrpa2physical
25009287
EIF3A_SCHPOtif32physical
25009287
MUG87_SCHPOnup97physical
25009287
YFR3_SCHPOslf1genetic
25009287
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SKB1_SCHPO

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Related Literatures of Post-Translational Modification

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