| UniProt ID | ORB6_SCHPO | |
|---|---|---|
| UniProt AC | O13310 | |
| Protein Name | Serine/threonine-protein kinase orb6 | |
| Gene Name | orb6 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 469 | |
| Subcellular Localization | ||
| Protein Description | Interacts with pak1/shk1 and coordinates cell morphogenesis with the cell cycle. It is essential for maintenance of cell polarity and is involved in mitotic control.. | |
| Protein Sequence | MDKNDYLHFERNPSLFPKSTLDKVQKTKKYIEHYYKVAVDHAVERNQRRINLEQRLATERGSEERKNRQLRASGEKESQFLRFRRTRLSLEDFSTIKVIGKGAFGEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVESDSPWVVSLYYAFQDSLYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKMATWKKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHETYRKIINWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQHPFFTGIDWDHIRETAAPFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVDPQTLEQTNLAFLGYTYKKFNYLTMKGAL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 464 | Phosphorylation | YKKFNYLTMKGAL-- HHHHCEEEECCCC-- | 13.38 | 29996109 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ORB6_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ORB6_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ORB6_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MOB2_SCHPO | mob2 | physical | 12456722 | |
| SKB1_SCHPO | skb1 | genetic | 12646585 | |
| SKB1_SCHPO | skb1 | physical | 12646585 | |
| NAK1_SCHPO | nak1 | physical | 16096637 | |
| MOR2_SCHPO | mor2 | physical | 16096637 | |
| ORB6_SCHPO | orb6 | physical | 12646585 | |
| PPK11_SCHPO | ppk11 | genetic | 20826805 | |
| GEF1_SCHPO | gef1 | genetic | 19646873 | |
| NAK1_SCHPO | nak1 | physical | 22629372 | |
| ORB6_SCHPO | orb6 | physical | 22629372 | |
| GEF1_SCHPO | gef1 | genetic | 12529446 | |
| SCD1_SCHPO | scd1 | genetic | 12529446 | |
| RGA4_SCHPO | rga4 | genetic | 19646873 | |
| MOB2_SCHPO | mob2 | physical | 23615447 | |
| MOR2_SCHPO | mor2 | physical | 23615447 | |
| ORB6_SCHPO | orb6 | physical | 23615447 | |
| GEF1_SCHPO | gef1 | physical | 26246599 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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