G3P1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: G3P1_SCHPO
• UniProt AC: P78958
• Protein Name: Glyceraldehyde-3-phosphate dehydrogenase 1
• Gene Name: tdh1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 336
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MAIPKVGINGFGRIGRIVLRNALVAKTIQVVAINDPFIDLEYMAYMFKYDSTHGRFDGSVEIKDGKLVIDGNAIDVHNERDPADIKWSTSGADYVIESTGVFTTQETASAHLKGGAKRVIISAPSKDAPMYVVGVNEEKFNPSEKVISNASCTTNCLAPLAKVINDTFGIEEGLMTTVHATTATQKTVDGPSKKDWRGGRGASANIIPSSTGAAKAVGKVIPALNGKLTGMAFRVPTPDVSVVDLTVKLAKPTNYEDIKAAIKAASEGPMKGVLGYTEDAVVSTDFCGDNHSSIFDASAGIQLSPQFVKLVSWYDNEWGYSRRVVDLVAYTAAKDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	THGRFDGSVEIKDGK CCCCCCCEEEEECCE	20.58	28889911
122	Phosphorylation	GAKRVIISAPSKDAP CCEEEEEECCCCCCC	24.01	28889911
125	Phosphorylation	RVIISAPSKDAPMYV EEEEECCCCCCCEEE	42.77	28889911
148	Phosphorylation	NPSEKVISNASCTTN CCCCCCCCCCCHHHC	29.36	29996109
151	Phosphorylation	EKVISNASCTTNCLA CCCCCCCCHHHCCHH	19.08	28889911
153	Phosphorylation	VISNASCTTNCLAPL CCCCCCHHHCCHHHH	20.67	28889911
154	Phosphorylation	ISNASCTTNCLAPLA CCCCCHHHCCHHHHH	28.41	28889911
176	Phosphorylation	GIEEGLMTTVHATTA CCCCCCEEEEEEEEC	30.61	24763107
177	Phosphorylation	IEEGLMTTVHATTAT CCCCCEEEEEEEECC	9.06	29996109
182	Phosphorylation	MTTVHATTATQKTVD EEEEEEEECCEECCC	28.61	28889911
184	Phosphorylation	TVHATTATQKTVDGP EEEEEECCEECCCCC	28.62	28889911
192	Phosphorylation	QKTVDGPSKKDWRGG EECCCCCCCCCCCCC	58.84	28889911
203	Phosphorylation	WRGGRGASANIIPSS CCCCCCCCCCCCCCC	25.36	28889911
209	Phosphorylation	ASANIIPSSTGAAKA CCCCCCCCCCCHHHH	30.08	28889911
210	Phosphorylation	SANIIPSSTGAAKAV CCCCCCCCCCHHHHH	26.04	28889911
211	Phosphorylation	ANIIPSSTGAAKAVG CCCCCCCCCHHHHHH	34.87	28889911
229	Phosphorylation	PALNGKLTGMAFRVP HHHCCEEEEEEEECC	28.53	21712547
237	Phosphorylation	GMAFRVPTPDVSVVD EEEEECCCCCCEEEE	29.30	28889911
241	Phosphorylation	RVPTPDVSVVDLTVK ECCCCCCEEEEEEEE	24.65	28889911
246	Phosphorylation	DVSVVDLTVKLAKPT CCEEEEEEEEECCCC	15.90	28889911
321	Phosphorylation	YDNEWGYSRRVVDLV CCCCCCCHHHHHHHH	15.07	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of G3P1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of G3P1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of G3P1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WIS4_SCHPO	wis4	physical	18406331
MCS4_SCHPO	mcs4	physical	20946853

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-59 AND SER-125, AND MASSSPECTROMETRY.
PubMed: 18257517