dbPTM

YFR3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YFR3_SCHPO
UniProt AC	Q9UT50
Protein Name	Uncharacterized protein C821.03c
Gene Name	SPAC821.03c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	485
Subcellular Localization
Protein Description
Protein Sequence	MSSIIQNPIESSYFVEDLSAVGNSQLHSGRSLTYGDRKANIDTRSGGGRRFWSNLNDSGNSFGAVPASSMNLSYGPTKSATISSKDGAMSRSSRYYVSSELKATLPSLDGRRLSKRNAANHASHHRMPDESASYRTRGEYESSSPRVPQKSLRRYYSTRTAQRLDVRRPASRSSRYSKTSDLPPSDPGRFVDDSDLTPHTDFTNRFVDSDFDPDSGVGRSSSPDQMMSRNNNLNINARMTSTSSKPYAKENQQLISSMAPVEQKNSFSTAREQYVAPALSFAEPVETQHNHMPKTTPLRGTSTVMNGSPIGPYSSSSNATGMYGVSKGHSSSTRRPFFSDVGSSQPAEEFVGSSSSHGRQQDSYIADDSDSERSYRRVRDQYLSKPRLSDKNRYSTFSEFPGQGTPSASQSNLRRSNTVRPTSFYYEKLHIKNDNPSFQALPYETTTQERKPVVKPDSIKTVKPEKKKSKGFFKKLMHKISHIFD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSIIQNPI ------CCCCCCCCC	30.19	29996109
3	Phosphorylation	-----MSSIIQNPIE -----CCCCCCCCCC	23.55	29996109
11	Phosphorylation	IIQNPIESSYFVEDL CCCCCCCCCCCCCCH	30.93	29996109
12	Phosphorylation	IQNPIESSYFVEDLS CCCCCCCCCCCCCHH	15.14	29996109
31	Phosphorylation	SQLHSGRSLTYGDRK CCCCCCCCCCCCCEE	28.70	25720772
53	Phosphorylation	GGGRRFWSNLNDSGN CCCCCCCCCCCCCCC	28.82	27738172
58	Phosphorylation	FWSNLNDSGNSFGAV CCCCCCCCCCCCCCE	38.51	25720772
61	Phosphorylation	NLNDSGNSFGAVPAS CCCCCCCCCCCEEHH	28.69	21712547
69	Phosphorylation	FGAVPASSMNLSYGP CCCEEHHHCCCCCCC	17.50	21712547
79	Phosphorylation	LSYGPTKSATISSKD CCCCCCCCCEEECCC	32.87	25720772
81	Phosphorylation	YGPTKSATISSKDGA CCCCCCCEEECCCCC	28.60	25720772
83	Phosphorylation	PTKSATISSKDGAMS CCCCCEEECCCCCCC	27.29	25720772
84	Phosphorylation	TKSATISSKDGAMSR CCCCEEECCCCCCCC	30.80	25720772
92	Phosphorylation	KDGAMSRSSRYYVSS CCCCCCCCCCEEECH	16.32	24763107
93	Phosphorylation	DGAMSRSSRYYVSSE CCCCCCCCCEEECHH	24.16	24763107
104	Phosphorylation	VSSELKATLPSLDGR ECHHHHHHCCCCCCH	37.30	21712547
107	Phosphorylation	ELKATLPSLDGRRLS HHHHHCCCCCCHHHH	42.05	29996109
114	Phosphorylation	SLDGRRLSKRNAANH CCCCHHHHHHHHCCH	27.97	21712547
131	Phosphorylation	HHRMPDESASYRTRG CCCCCCCCCCCCCCC	29.87	29996109
133	Phosphorylation	RMPDESASYRTRGEY CCCCCCCCCCCCCCC	25.15	29996109
134	Phosphorylation	MPDESASYRTRGEYE CCCCCCCCCCCCCCC	18.73	29996109
136	Phosphorylation	DESASYRTRGEYESS CCCCCCCCCCCCCCC	34.49	29996109
142	Phosphorylation	RTRGEYESSSPRVPQ CCCCCCCCCCCCCCH	34.90	29996109
143	Phosphorylation	TRGEYESSSPRVPQK CCCCCCCCCCCCCHH	32.21	29996109
144	Phosphorylation	RGEYESSSPRVPQKS CCCCCCCCCCCCHHH	26.46	29996109
179	Phosphorylation	RSSRYSKTSDLPPSD CCCCCCCCCCCCCCC	22.87	29996109
180	Phosphorylation	SSRYSKTSDLPPSDP CCCCCCCCCCCCCCC	40.67	29996109
209	Phosphorylation	FTNRFVDSDFDPDSG CCCCCCCCCCCCCCC	34.57	29996109
215	Phosphorylation	DSDFDPDSGVGRSSS CCCCCCCCCCCCCCC	40.54	25720772
220	Phosphorylation	PDSGVGRSSSPDQMM CCCCCCCCCCHHHHH	29.28	25720772
221	Phosphorylation	DSGVGRSSSPDQMMS CCCCCCCCCHHHHHH	44.52	29996109
222	Phosphorylation	SGVGRSSSPDQMMSR CCCCCCCCHHHHHHC	33.47	28889911
241	Phosphorylation	NINARMTSTSSKPYA CCCEEECCCCCCCCH	19.56	27738172
256	Phosphorylation	KENQQLISSMAPVEQ HHHHHHHHHCCCHHH	23.74	21712547
257	Phosphorylation	ENQQLISSMAPVEQK HHHHHHHHCCCHHHC	16.39	21712547
266	Phosphorylation	APVEQKNSFSTAREQ CCHHHCCCCHHHHHH	27.84	25720772
268	Phosphorylation	VEQKNSFSTAREQYV HHHCCCCHHHHHHHH	22.45	21712547
269	Phosphorylation	EQKNSFSTAREQYVA HHCCCCHHHHHHHHH	27.94	21712547
274	Phosphorylation	FSTAREQYVAPALSF CHHHHHHHHHHHHHC	8.20	21712547
280	Phosphorylation	QYVAPALSFAEPVET HHHHHHHHCCCCCCC	25.23	21712547
287	Phosphorylation	SFAEPVETQHNHMPK HCCCCCCCCCCCCCC	35.05	29996109
295	Phosphorylation	QHNHMPKTTPLRGTS CCCCCCCCCCCCCCE	27.98	21712547
301	Phosphorylation	KTTPLRGTSTVMNGS CCCCCCCCEEEECCC	18.13	27738172
308	Phosphorylation	TSTVMNGSPIGPYSS CEEEECCCCCCCCCC	14.35	21712547
343	Phosphorylation	PFFSDVGSSQPAEEF CCCCCCCCCCCHHHH	26.16	29996109
344	Phosphorylation	FFSDVGSSQPAEEFV CCCCCCCCCCHHHHC	33.96	29996109
353	Phosphorylation	PAEEFVGSSSSHGRQ CHHHHCCCCCCCCCC	23.03	25720772
354	Phosphorylation	AEEFVGSSSSHGRQQ HHHHCCCCCCCCCCC	29.90	29996109
355	Phosphorylation	EEFVGSSSSHGRQQD HHHCCCCCCCCCCCC	28.22	25720772
356	Phosphorylation	EFVGSSSSHGRQQDS HHCCCCCCCCCCCCC	31.73	25720772
369	Phosphorylation	DSYIADDSDSERSYR CCCCCCCCCCHHHHH	43.51	25720772
371	Phosphorylation	YIADDSDSERSYRRV CCCCCCCCHHHHHHH	38.57	25720772
374	Phosphorylation	DDSDSERSYRRVRDQ CCCCCHHHHHHHHHH	20.95	25720772
375	Phosphorylation	DSDSERSYRRVRDQY CCCCHHHHHHHHHHH	14.52	25720772
395	Phosphorylation	LSDKNRYSTFSEFPG CCCCCCCCCCCCCCC	21.53	29996109
396	Phosphorylation	SDKNRYSTFSEFPGQ CCCCCCCCCCCCCCC	23.42	29996109
398	Phosphorylation	KNRYSTFSEFPGQGT CCCCCCCCCCCCCCC	38.11	29996109
405	Phosphorylation	SEFPGQGTPSASQSN CCCCCCCCCCHHHHH	13.24	29996109
407	Phosphorylation	FPGQGTPSASQSNLR CCCCCCCCHHHHHHC	40.15	29996109
409	Phosphorylation	GQGTPSASQSNLRRS CCCCCCHHHHHHCCC	38.18	29996109
411	Phosphorylation	GTPSASQSNLRRSNT CCCCHHHHHHCCCCC	35.02	29996109
416	Phosphorylation	SQSNLRRSNTVRPTS HHHHHCCCCCCCCCC	30.34	25720772
418	Phosphorylation	SNLRRSNTVRPTSFY HHHCCCCCCCCCCCE	21.09	29996109
422	Phosphorylation	RSNTVRPTSFYYEKL CCCCCCCCCCEEEEE	22.39	29996109
423	Phosphorylation	SNTVRPTSFYYEKLH CCCCCCCCCEEEEEE	17.59	29996109
425	Phosphorylation	TVRPTSFYYEKLHIK CCCCCCCEEEEEEEC	15.52	29996109
426	Phosphorylation	VRPTSFYYEKLHIKN CCCCCCEEEEEEECC	12.46	29996109
437	Phosphorylation	HIKNDNPSFQALPYE EECCCCCCCCCCCCC	35.92	28889911
446	Phosphorylation	QALPYETTTQERKPV CCCCCCCCCCCCCCC	17.97	21712547
447	Phosphorylation	ALPYETTTQERKPVV CCCCCCCCCCCCCCC	35.53	25720772
458	Phosphorylation	KPVVKPDSIKTVKPE CCCCCCCCCCCCCCC	34.22	28889911
461	Phosphorylation	VKPDSIKTVKPEKKK CCCCCCCCCCCCHHH	31.90	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YFR3_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YFR3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YFR3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SKB1_SCHPO	skb1	physical	25009287
SEC6_SCHPO	sec6	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YFR3_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-222 AND SER-458, ANDMASS SPECTROMETRY.	18257517 [Abstract]