dbPTM

PPR8_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PPR8_SCHPO
UniProt AC	O94615
Protein Name	Pentatricopeptide repeat-containing protein 8, mitochondrial
Gene Name	ppr8
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	481
Subcellular Localization	Mitochondrion .
Protein Description	Mitochondrial RNA-binding protein involved in mitochondrial translation. The cox1 mRNA is one target but it is not clear if ppr8 has a single or multiple targets..
Protein Sequence	MQGFGSQIFRKLLRSSNAKVSDALLQNTRTLFTAPPLHSGLQTSFTAETQQHVRQNSQNLLKQLNDEMKARKYTETVATFSSLKPFGILDSQTINRYILFLVDRIKMLNGRGNVDEATLDKLDDILRYAIEHQEIASARFWRIMLQSYIDLNLFDKASLIADMSLSHMEFLPKDERVLGNLYISALQAKILGGASFEQCGKIGSAIHEQLEGKEVVNELVAVYLIYTVFKDQGISSKAHKALVQFNGLTSFHSDVIISVFVNKGLVDQAAAYLKNSNLNERNLPTIYTTVWLLQRLFEAHHSLDPLLTIFDYYLSVSPKDITRLTNAILSLSMKQFERDRDIKKATDFITTFINKMSDVKEFKPSISTANTLFSIASRLKDVKWLSAGFDMIDKYGLKPTHVTYRSLLKAYCLLPSTCEQISQAWVNLEYRLEAISISVADKEINLLKDCILSQPDRDDQQSCLQFLNMVLSKYGKHIRSP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
346	Phosphorylation	DRDIKKATDFITTFI HHHHHHHHHHHHHHH	40.08	25720772
351	Phosphorylation	KATDFITTFINKMSD HHHHHHHHHHHHHHC	20.08	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PPR8_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PPR8_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PPR8_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PPR8_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PPR8_SCHPO

Related Literatures of Post-Translational Modification