TRM82_SCHPO - dbPTM
TRM82_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TRM82_SCHPO
UniProt AC O74863
Protein Name tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82 {ECO:0000255|HAMAP-Rule:MF_03056}
Gene Name trm82
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 421
Subcellular Localization Nucleus .
Protein Description Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit..
Protein Sequence MSEQRVFKHPCQFLTWNSKHNYIVCCSGPYLLGFSCSTGEKIFEHCYRDNINEKHREAAAYGEAIRQVAFSKDYSRMATVSEDKCLRLWDSTQPDKIELLYQKNIPKRCADLCFAGSNEIVFGDKFGDVYCVDENWFTTSEVTEEKKSNVVEGKQEPVNNDTLKDSKLQKLEPIMGHVSILTQLIVAQNPQNSKEEIIITSDKDEHIRISRFPNAFVIEGFCLGHEDFVSRMSLYDNRTLISGGGDNHVFVWDLENFKCLDAFDLRSAFSTYLSLNQPMVVSVILPIFKRQLVAFACEGMAGLIFAKVTPEKRLLFHSALKLSGPVLDAVLLDTDTDQILISLDSSFTFGACFECVKFDEGNAAVLTKPDVIKRIESDGLISTEKPFCPLAQIHTLRKNHSKFIRSVETGTSSPSVESKDN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
406PhosphorylationNHSKFIRSVETGTSS
HHHHHHEECCCCCCC		21.3521712547
409PhosphorylationKFIRSVETGTSSPSV
HHHEECCCCCCCCCC		43.5321712547
411PhosphorylationIRSVETGTSSPSVES
HEECCCCCCCCCCCC		33.1925720772
412PhosphorylationRSVETGTSSPSVESK
EECCCCCCCCCCCCC		41.4129996109
413PhosphorylationSVETGTSSPSVESKD
ECCCCCCCCCCCCCC		22.4928889911
415PhosphorylationETGTSSPSVESKDN-
CCCCCCCCCCCCCC-		40.2325720772
418PhosphorylationTSSPSVESKDN----
CCCCCCCCCCC----		43.0621712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TRM82_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TRM82_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TRM82_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MPH1L_SCHPOmph1genetic
22681890
PCK1_SCHPOpck1genetic
22681890
YNU4_SCHPOSPBC28E12.04genetic
22681890
PROB_SCHPOSPAC17H9.13cgenetic
22681890
ERG28_SCHPOerg28genetic
22681890
MU178_SCHPOmug178genetic
22681890
XPOT_SCHPOlos1genetic
22681890
YF48_SCHPOSPAC3H5.08cgenetic
22681890
ARP8_SCHPOarp8genetic
22681890
HEM2_SCHPOhem2genetic
22681890
PUS4_SCHPOSPBC11C11.10genetic
22681890
TRM10_SCHPOtrm10genetic
22681890
YE04_SCHPOSPAC17H9.04cgenetic
22681890
BST1_SCHPObst1genetic
22681890
TRMB_SCHPOtrm8genetic
22681890
YLO2_SCHPOtma23genetic
22681890
SWD1_SCHPOswd1genetic
22681890
ARP42_SCHPOarp42genetic
22681890
RIA1_SCHPOria1genetic
22681890
ATP12_SCHPOatp12genetic
22681890
ASH2_SCHPOash2genetic
22681890
NOT3_SCHPOnot3genetic
22681890
DUS2_SCHPOdus2genetic
22681890
YET4_SCHPOSPAC8C9.04genetic
22681890
TPSY_SCHPOSPAC22F8.05genetic
22681890
BUT1_SCHPObut1genetic
22681890
YOR2_SCHPOrng9genetic
22681890
FKBP4_SCHPOfkbp39genetic
22681890
YD49_SCHPOSPAC22H10.09genetic
22681890
RL38A_SCHPOrpl3801genetic
22681890
PTPA1_SCHPOypa1genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
FFT3_SCHPOfft3genetic
22681890
RPB9_SCHPOrpb9genetic
22681890
TRM6_SCHPOgcd10genetic
22681890
DAD2_SCHPOdad2genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
YKN4_SCHPOmca1genetic
22681890
CGM2_SCHPOmcs2genetic
22681890
TBA2_SCHPOatb2genetic
22681890
MID1_SCHPOmid1genetic
22681890
MU154_SCHPOmug154genetic
22681890
ARC1_SCHPOSPAC30C2.04genetic
22681890
PPK2_SCHPOtea5genetic
22681890
YOX1_SCHPOyox1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TRM82_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-413, AND MASSSPECTROMETRY.

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