dbPTM

CGM2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CGM2_SCHPO
UniProt AC	P36613
Protein Name	Cyclin mcs2
Gene Name	mcs2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	322
Subcellular Localization	Nucleus .
Protein Description	Essential for progression through the cell cycle. Posseses kinase activity that can be detected when myelin basic protein (MBP) is provided as an exogenous substrate..
Protein Sequence	MSADKFRDSTHYRDWIFTEEDLSKTRAKVNEKFTNIVRERMLEELSLQNKEASLEVLPPTLTVEEELELVNYYSFQLNALSSALSLPTHIRSTAILFFKRFYLINSVMEYSPKIISFTSLFLATKCNDHYISIEQFCKNMPKTTPEEVLEYEFNVCQSLKWDLYVWLPFRPLQGFLLDCQTVLPKVAVEKFYECHDLSKKFLIETLHSDIYFLHSPSIIALGAIYHTNPTICLQYIEAKKIPELQPLIISISANLKATKKFKIEKKKAQDYGRKLYFCMNPLRNKSSALYLKRKAEEESTNNNKWAKKFSTSSNVLDKNPFE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
310	Phosphorylation	NKWAKKFSTSSNVLD CHHHHHHCCCCCCCC	35.94	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CGM2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CGM2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CGM2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CSK1_SCHPO	csk1	genetic	8467814
CDK1_SCHPO	cdc2	genetic	2474475
CRK1_SCHPO	mcs6	genetic	8557037
CRK1_SCHPO	mcs6	physical	8557036
SKP1_SCHPO	skp1	physical	15555586
DHE4_SCHPO	gdh1	genetic	22681890
YBX5_SCHPO	SPBC17D1.05	genetic	22681890
DPH2_SCHPO	dph2	genetic	22681890
YCRE_SCHPO	trs130	genetic	22681890
YG58_SCHPO	SPBC56F2.08c	genetic	22681890
PUB1_SCHPO	pub1	genetic	22681890
HRP3_SCHPO	hrp3	genetic	22681890
VID27_SCHPO	SPBC1685.14c	genetic	22681890
WTF16_SCHPO	wtf16	genetic	22681890
RCQ1_SCHPO	rqc1	genetic	22681890
GET3_SCHPO	get3	genetic	22681890
BQT3_SCHPO	bqt3	genetic	22681890
SDS23_SCHPO	sds23	genetic	22681890
HAT1_SCHPO	hat1	genetic	22681890
YAN6_SCHPO	SPAC3H1.06c	genetic	22681890
SWI6_SCHPO	swi6	genetic	22681890
YHD6_SCHPO	SPBC1683.06c	genetic	22681890
BQT4_SCHPO	bqt4	genetic	22681890
DPH3_SCHPO	dph3	genetic	22681890
ADG2_SCHPO	adg2	genetic	22681890
YM06_SCHPO	SPAC212.06c	genetic	22681890
YLZ1_SCHPO	SPAC750.01	genetic	22681890
YCGK_SCHPO	SPCC16C4.20c	genetic	22681890
G3P2_SCHPO	gpd3	genetic	22681890
ARGI1_SCHPO	car1	genetic	22681890
PROB_SCHPO	SPAC17H9.13c	genetic	22681890
LYS1_SCHPO	lys3	genetic	22681890
BADH_SCHPO	atd3	genetic	22681890
SPN3_SCHPO	spn3	genetic	22681890
RT109_SCHPO	rtt109	genetic	22681890
EFTS_SCHPO	tsf1	genetic	22681890
YJ03_SCHPO	rhn1	genetic	22681890
YGDH_SCHPO	SPBC1773.17c	genetic	22681890
TRK1_SCHPO	trk1	genetic	22681890
ALG6_SCHPO	alg6	genetic	22681890
APT_SCHPO	apt1	genetic	22681890
YAC5_SCHPO	cph1	genetic	22681890
AP2M_SCHPO	apm4	genetic	22681890
CIP1_SCHPO	cip1	genetic	22681890
YAF9_SCHPO	SPAC29E6.09	genetic	22681890
DEP1_SCHPO	dep1	genetic	22681890
KPR5_SCHPO	prs5	genetic	22681890
CCQ1_SCHPO	ccq1	genetic	22681890
TRM10_SCHPO	trm10	genetic	22681890
AYR1_SCHPO	ayr1	genetic	22681890
YE04_SCHPO	SPAC17H9.04c	genetic	22681890
BST1_SCHPO	bst1	genetic	22681890
MU155_SCHPO	mug155	genetic	22681890
NEM1_SCHPO	nem1	genetic	22681890
YGRG_SCHPO	SPBC365.16	genetic	22681890
CAT1_SCHPO	cat1	genetic	22681890
CHP1_SCHPO	chp1	genetic	22681890
OXR1_SCHPO	mug63	genetic	22681890
YC1B_SCHPO	msy1	genetic	22681890
RAV1_SCHPO	rav1	genetic	22681890
BUN62_SCHPO	bun62	genetic	22681890
FUS1_SCHPO	fus1	genetic	22681890
MET10_SCHPO	SPCC584.01c	genetic	22681890
SNF5_SCHPO	snf5	genetic	22681890
GYP1_SCHPO	gyp1	genetic	22681890
OTC_SCHPO	arg3	genetic	22681890
YGI2_SCHPO	SPBC2A9.02	genetic	22681890
GSK3_SCHPO	gsk3	genetic	22681890
TMA20_SCHPO	tma20	genetic	22681890
YETB_SCHPO	fra2	genetic	22681890
YL89_SCHPO	SPAC25B8.09	genetic	22681890
GAS5_SCHPO	gas5	genetic	22681890
YJD4_SCHPO	SPCC594.04c	genetic	22681890
RSC4_SCHPO	rsc4	genetic	22681890
NAGS_SCHPO	arg6	genetic	22681890
MU129_SCHPO	mug129	genetic	22681890
YL43_SCHPO	SPAC323.03c	genetic	22681890
PHD1_SCHPO	hos2	genetic	22681890
PAN3_SCHPO	ppk26	genetic	22681890
FCF2_SCHPO	fcf2	genetic	22681890
REC11_SCHPO	rec11	genetic	22681890
MSC1_SCHPO	msc1	genetic	22681890
SGF73_SCHPO	sgf73	genetic	22681890
ASH2_SCHPO	ash2	genetic	22681890
NOT3_SCHPO	not3	genetic	22681890
PNK1_SCHPO	pnk1	genetic	22681890
YJFB_SCHPO	SPCC306.11	genetic	22681890
SUMT_SCHPO	SPCC1739.06c	genetic	22681890
FSV1_SCHPO	fsv1	genetic	22681890
YF19_SCHPO	atd1	genetic	22681890
HOSM_SCHPO	lys4	genetic	22681890
GPA2_SCHPO	gpa2	genetic	22681890
DTD_SCHPO	SPAC8C9.05	genetic	22681890
MFM2_SCHPO	mfm2	genetic	22681890
ANM3_SCHPO	rmt3	genetic	22681890
NU124_SCHPO	nup124	genetic	22681890
LYS4_SCHPO	lys2	genetic	22681890
SOL1_SCHPO	sol1	genetic	22681890
APQ12_SCHPO	apq12	genetic	22681890
TLS1_SCHPO	tls1	genetic	22681890
ING2_SCHPO	png2	genetic	22681890
YKT4_SCHPO	SPAPB1E7.04c	genetic	22681890
YDHE_SCHPO	SPAC6G9.14	genetic	22681890
MUG20_SCHPO	mug20	genetic	22681890
SPC2_SCHPO	spc2	genetic	22681890
ATG20_SCHPO	atg20	genetic	22681890
MMS19_SCHPO	mms19	genetic	22681890
PTR2_SCHPO	ptr2	genetic	22681890
YCPF_SCHPO	SPCC663.15c	genetic	22681890
YCF8_SCHPO	SPCC1393.08	genetic	22681890
POF3_SCHPO	pof3	genetic	22681890
YGVA_SCHPO	def1	genetic	22681890
RAF1_SCHPO	raf1	genetic	22681890
ELP1_SCHPO	elp1	genetic	22681890
MBX1_SCHPO	mbx1	genetic	22681890
YAUB_SCHPO	SPAC26A3.11	genetic	22681890
HSP71_SCHPO	ssa1	genetic	22681890
ATP11_SCHPO	atp11	genetic	22681890
YBKD_SCHPO	gmh6	genetic	22681890
MST2_SCHPO	mst2	genetic	22681890
PTF2_SCHPO	ptf2	genetic	22681890
OMH1_SCHPO	omh1	genetic	22681890
YQ9H_SCHPO	SPCC18.17c	genetic	22681890
RDH54_SCHPO	rdh54	genetic	22681890
ARG56_SCHPO	arg11	genetic	22681890
YE87_SCHPO	SPAC9G1.07	genetic	22681890
SET6_SCHPO	set6	genetic	22681890
MDE6_SCHPO	mde6	genetic	22681890
MED1_SCHPO	pmc2	genetic	22681890
CTK3_SCHPO	lsg1	genetic	22681890
MCP2_SCHPO	mcp2	genetic	22681890
ALM1_SCHPO	alm1	genetic	22681890
BIOB_SCHPO	bio2	genetic	22681890
YCY1_SCHPO	SPCC1235.01	genetic	22681890
TRM82_SCHPO	SPCC18.13	genetic	22681890
BUT2_SCHPO	but2	genetic	22681890
SAT1_SCHPO	sat1	genetic	22681890
RDS1_SCHPO	rds1	genetic	22681890
YFY7_SCHPO	SPAC9.07c	genetic	22681890
OCA2_SCHPO	oca2	genetic	22681890
RAP1_SCHPO	rap1	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
YD22_SCHPO	SPAC56F8.02	genetic	22681890
YK1D_SCHPO	SPAPB1A10.13	genetic	22681890
POF15_SCHPO	pof15	genetic	22681890
YHEI_SCHPO	SPBPB2B2.18	genetic	22681890
RR14N_SCHPO	rrp14	genetic	22681890
IMA2_SCHPO	imp1	genetic	22681890
YOH8_SCHPO	leo1	genetic	22681890
MU154_SCHPO	mug154	genetic	22681890
MPC1_SCHPO	mpc1	genetic	22681890
EMC1_SCHPO	emc1	genetic	22681890
PRZ1_SCHPO	prz1	genetic	22681890
CSK1_SCHPO	csk1	genetic	22681890
EHS1_SCHPO	yam8	genetic	22681890
ASSY_SCHPO	arg12	genetic	22681890
YIW2_SCHPO	SPAC694.02	genetic	22681890
YDA3_SCHPO	SPAC1F12.03c	genetic	22681890
YI43_SCHPO	SPBC1348.03	genetic	22681890
RGA8_SCHPO	rga8	genetic	22681890
AMT2_SCHPO	amt2	genetic	22681890
ULP1_SCHPO	ulp1	genetic	22681890
SSN2_SCHPO	med13	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CGM2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-310, AND MASSSPECTROMETRY.	18257517 [Abstract]