BUN62_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BUN62_SCHPO
• UniProt AC: Q10437
• Protein Name: UBP9-binding protein bun62
• Gene Name: bun62
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 543
• Subcellular Localization: Nucleus. Cytoplasm. Cell septum. Cell tip.
• Protein Description: Required for the ubp9 recruitment to septa and cell tips but also for its enzymatic activity at these specific locations..
• Protein Sequence: MQTMSSGIARPVLFLTAREGEYVLKDEFQLGSSSRSTPQITGSPLDPNTPVKRLFFMRINIAQFSRWDYPYPREYIEELKKIHGVHHVEENRDVPSILENYRNSKRKSHNFSSSNTPYLKLHRPASRAGAPLINAKSFISSLTFHDNIVRSFQPSIHGKTFVFANHEKSFYWLDVSAANSHSALLKMEFPRASPVCHDINSFTKSPKGLDVIIGFDTGDVLWYDPINFKYLRFNKNGQLNSSSVTAIKWVAGKDSQFLVSFRNGWLVLYDKYRHEQPLHIVVPEKNLKSLYLSSPGTFNILISINHRDDRKLNPVACYAFSKSPINGFCFSPDYQYLALVSERGTLKLFDFVKEHVLDVFHSYFAGLTCVTWSPDGKFIAIGGKDDLVSIYSFPLRKLVARCQGHKSWVTDVIFDAWRCDDDNYRIASVGLDRKLLLWDFSVSAIHRPKSAVYYVNHHSNNSKPAISDFDDVGDLTMGSEIDNSNYVNGDITIHPTLSRSLIPVISPITIYDVDDSPLSSVFFDPDCMITCATNGRIRTWQRP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	LGSSSRSTPQITGSP CCCCCCCCCCCCCCC	20.36	28889911
41	Phosphorylation	SRSTPQITGSPLDPN CCCCCCCCCCCCCCC	26.76	21712547
43	Phosphorylation	STPQITGSPLDPNTP CCCCCCCCCCCCCCC	17.40	28889911
108	Phosphorylation	YRNSKRKSHNFSSSN HHCCCCCCCCCCCCC	27.91	28889911
113	Phosphorylation	RKSHNFSSSNTPYLK CCCCCCCCCCCCCEE	24.38	29996109
114	Phosphorylation	KSHNFSSSNTPYLKL CCCCCCCCCCCCEEE	43.45	21712547
126	Phosphorylation	LKLHRPASRAGAPLI EEECCCHHHCCCCCC	25.91	21712547
450	Phosphorylation	SAIHRPKSAVYYVNH EEECCCCEEEEEEEC	26.16	21712547
453	Phosphorylation	HRPKSAVYYVNHHSN CCCCEEEEEEECCCC	11.04	21712547
454	Phosphorylation	RPKSAVYYVNHHSNN CCCEEEEEEECCCCC	6.54	21712547
459	Phosphorylation	VYYVNHHSNNSKPAI EEEEECCCCCCCCCC	30.10	24763107
462	Phosphorylation	VNHHSNNSKPAISDF EECCCCCCCCCCCCC	44.24	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BUN62_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BUN62_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BUN62_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBP9_SCHPO	ubp9	physical	20838651

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-43, AND MASSSPECTROMETRY.
PubMed: 18257517