BQT4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BQT4_SCHPO
• UniProt AC: O60158
• Protein Name: Bouquet formation protein 4
• Gene Name: bqt4
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 432
• Subcellular Localization: Cytoplasm . Nucleus . Nucleus inner membrane ; Peripheral membrane protein .
• Protein Description: Connects telomeres to the nuclear envelop (NE) during both vegetative growth and meiosis. This connection ensures clustering of telomeres to the spindle pole body (SPB) when cells enter meiotic prophase..
• Protein Sequence: MTENEKSRSLPAERNPLYKDDTLDHTPLIPKCRAQVIEFPDGPATFVRLKCTNPESKVPHFLMRMAKDSSISATSMFRSAFPKATQEEEDLEMRWIRDNLNPIEDKRVAGLWVPPADALALAKDYSMTPFINALLEASSTPSTYATPSRPTAQKSETSEGEPESSTSATTTSVARRTRQRLAEHLENSKKTILQHDNKEEDKEIHSEENETKDEIKSEKKEPEIKKQEGGSSTEKVGQPSSSDDKAKGSTSKDQPSEEEEKTSDIQDRKIKTPIKPSLLGKIRSSVNKGMTDVASQVNRGMTDVASQVNKGVNGVASQVNKGMNGVANQVNKGVTGVASQVRKPVGKLEKKFENLEKSIGDTLKSSIRSSPKSKKRSREDFEENEDYNAMVPVKRSRITKLESEVYYEKRKVRALGGIAIGLGVGAILPFLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	KDDTLDHTPLIPKCR CCCCCCCCCCCHHHC	21.32	24763107
138	Phosphorylation	INALLEASSTPSTYA HHHHHHHCCCCCCCC	25.93	29996109
139	Phosphorylation	NALLEASSTPSTYAT HHHHHHCCCCCCCCC	51.92	29996109
140	Phosphorylation	ALLEASSTPSTYATP HHHHHCCCCCCCCCC	20.82	29996109
142	Phosphorylation	LEASSTPSTYATPSR HHHCCCCCCCCCCCC	33.85	24763107
143	Phosphorylation	EASSTPSTYATPSRP HHCCCCCCCCCCCCC	20.55	24763107
144	Phosphorylation	ASSTPSTYATPSRPT HCCCCCCCCCCCCCC	16.89	21712547
146	Phosphorylation	STPSTYATPSRPTAQ CCCCCCCCCCCCCCC	16.04	29996109
148	Phosphorylation	PSTYATPSRPTAQKS CCCCCCCCCCCCCCC	46.68	29996109
155	Phosphorylation	SRPTAQKSETSEGEP CCCCCCCCCCCCCCC	33.74	29996109
157	Phosphorylation	PTAQKSETSEGEPES CCCCCCCCCCCCCCC	38.89	29996109
158	Phosphorylation	TAQKSETSEGEPESS CCCCCCCCCCCCCCC	39.28	29996109
169	Phosphorylation	PESSTSATTTSVARR CCCCCCHHHHHHHHH	30.30	29996109
170	Phosphorylation	ESSTSATTTSVARRT CCCCCHHHHHHHHHH	19.45	29996109
171	Phosphorylation	SSTSATTTSVARRTR CCCCHHHHHHHHHHH	19.49	29996109
172	Phosphorylation	STSATTTSVARRTRQ CCCHHHHHHHHHHHH	16.22	29996109
206	Phosphorylation	EEDKEIHSEENETKD HHHHHHHHCCCCCHH	52.87	21712547
211	Phosphorylation	IHSEENETKDEIKSE HHHCCCCCHHHHHHH	56.21	21712547
241	Phosphorylation	EKVGQPSSSDDKAKG CCCCCCCCCCCCCCC	44.46	29996109
256	Phosphorylation	STSKDQPSEEEEKTS CCCCCCCCHHHHHCC	52.59	29996109
272	Phosphorylation	IQDRKIKTPIKPSLL CHHCCCCCCCCHHHH	33.45	28889911
284	Phosphorylation	SLLGKIRSSVNKGMT HHHHHHHHHHHCCHH	41.95	21712547
285	Phosphorylation	LLGKIRSSVNKGMTD HHHHHHHHHHCCHHH	21.62	21712547
369	Phosphorylation	TLKSSIRSSPKSKKR HHHHHHHCCCCCCCC	49.69	24763107
370	Phosphorylation	LKSSIRSSPKSKKRS HHHHHHCCCCCCCCC	26.88	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BQT4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BQT4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BQT4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DOHH_SCHPO	mmd1	genetic	18931302
ASE1_SCHPO	ase1	genetic	18931302
DYL1_SCHPO	dlc2	genetic	18931302
RAP1_SCHPO	rap1	physical	22959349

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.