OCA2_SCHPO - dbPTM
OCA2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OCA2_SCHPO
UniProt AC O59763
Protein Name Serine/threonine-protein kinase oca2
Gene Name oca2 {ECO:0000312|EMBL:CAA18998.1}
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 650
Subcellular Localization Cytoplasm . Barrier septum. Cell tip.
Protein Description Overexpression causes cell cycle arrest..
Protein Sequence MSVTPPNVQFNLNGDSDHKSDNSSSSLENKLDTELKITSPPRNPPQRLHPVDFSEHADTDDDMNHPLPRVQSPVHIKNHIDPKLAEDRYRSSAARHFEPISIPPSAITSEDEDDYHGSANSSTVLPPRTENALHAASPKPSGSTGYTSPALSQNSGSGGEGESDEGSFNTQHHRSPIFQAYPSSEDLVGDPNDPYRRTRRAPIKTNPHDIPSQFIFRKLGLHHGKHGHHGHSGSLSLKSLVPNHHDKHDKHDKHEKHHSSLDLRRFFKSHQKTDKEKKPSVSKSKSSANLQDDHFGLFKKYGKFGRMLGSGAGGSVRIMKRSSDGKIFAVKEFRARRPTETEREYARKVTAEFCIGSALHHTNIIETLDIVEENKKFYEVMEYAPYDMFSIVMSGKMTMPEVYCCFKQLLSGVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAPETLVRKLYDPRAVDIWSSAIIFCCMALRRFPWKYPKLSDNSFRLFCMKQPSNDAESPSDILADIKKQRLVEQGCEPIRKTDESHSPNSKTDNSSTHKQELYGPWRLLRLLPRETRAVIAHMLELDPVKRYDIHRVFADNWINDISMCHMENGKVIHSPTHVHNLVASEESPAPPAKH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSVTPPNVQ
------CCCCCCCEE		34.4021712547
4Phosphorylation----MSVTPPNVQFN
----CCCCCCCEEEE		26.2221712547
16PhosphorylationQFNLNGDSDHKSDNS
EEECCCCCCCCCCCC		42.9121712547
26PhosphorylationKSDNSSSSLENKLDT
CCCCCCHHHHHHHCC		41.4728889911
38PhosphorylationLDTELKITSPPRNPP
HCCCCEECCCCCCCC		33.3329996109
39PhosphorylationDTELKITSPPRNPPQ
CCCCEECCCCCCCCC		36.0629996109
54PhosphorylationRLHPVDFSEHADTDD
CCCCCCCCCCCCCCC		24.8229996109
59PhosphorylationDFSEHADTDDDMNHP
CCCCCCCCCCCCCCC		41.9529996109
72PhosphorylationHPLPRVQSPVHIKNH
CCCCCCCCCHHHHCC		26.4928889911
175PhosphorylationFNTQHHRSPIFQAYP
CCCCCCCCCCCCCCC		20.2828889911
181PhosphorylationRSPIFQAYPSSEDLV
CCCCCCCCCCHHHCC		7.8929996109
183PhosphorylationPIFQAYPSSEDLVGD
CCCCCCCCHHHCCCC		33.4129996109
184PhosphorylationIFQAYPSSEDLVGDP
CCCCCCCHHHCCCCC		30.5329996109
259PhosphorylationDKHEKHHSSLDLRRF
CHHHHHHHHHHHHHH		32.1128889911
284PhosphorylationKKPSVSKSKSSANLQ
CCCCCCCCCCCCCCC		30.2021712547
286PhosphorylationPSVSKSKSSANLQDD
CCCCCCCCCCCCCCC		41.6028889911
287PhosphorylationSVSKSKSSANLQDDH
CCCCCCCCCCCCCCC		25.5529996109
322PhosphorylationSVRIMKRSSDGKIFA
CEEEEEECCCCCEEE		27.5428889911
524PhosphorylationLFCMKQPSNDAESPS
EEEECCCCCCCCCHH		44.8628889911
558PhosphorylationRKTDESHSPNSKTDN
CCCCCCCCCCCCCCC		34.7521712547
561PhosphorylationDESHSPNSKTDNSST
CCCCCCCCCCCCCHH		40.0721712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OCA2_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OCA2_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OCA2_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PDP2_SCHPOSPBC215.07cgenetic
22681890
EIF2A_SCHPOSPBC4B4.04genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
GET1_SCHPOget1genetic
22681890
SNF5_SCHPOsnf5genetic
22681890
TMA20_SCHPOtma20genetic
22681890
ERG5_SCHPOerg5genetic
22681890
DSC4_SCHPOdsc4genetic
22681890
POF3_SCHPOpof3genetic
22681890
JMJ2_SCHPOjmj2genetic
22681890
PTPA1_SCHPOypa1genetic
22681890
CGM2_SCHPOmcs2genetic
22681890
YJ2D_SCHPOSPCC4B3.13genetic
22681890
RL19B_SCHPOrpl1902genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OCA2_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-72 AND SER-286, AND MASSSPECTROMETRY.

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