POF3_SCHPO - dbPTM
POF3_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID POF3_SCHPO
UniProt AC O74991
Protein Name F-box/TPR repeat protein pof3
Gene Name pof3
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 577
Subcellular Localization Mitochondrion. Nucleus.
Protein Description Has a role in substrate recognition in the Skp1-Cullin-1/Cdc53-F-box (SCF) ubiquitin ligase complex. Required for the maintenance of telomere length and transcriptional silencing at the telomere. Also required for chromosome segregation..
Protein Sequence MNNYQVKAIKEKTQQYLSKRKFEDALTFITKTIEQEPNPTIDLFELRAQVYEKSGQYSQAELDAKRMIHLNARNARGYLRLGKLLQLDGFDKKADQLYTQGLRMVHKMDPLRPVLKKVSQRLNERILRTRPVLDLFRILPREVLLCILQQLNFKSIVQCMQVCKHWRDCIKKEPSLFCCLDFSCASPRSVNSRDRNVMAVARYSVYSKDNIQEVIGLEKLGILTPTKALLRSVKSLKVYKTISPLHTQSTDKLYTIWTPFSELHYFYCATPITFSIASKILSCCKKLKQVELVDLIPDLIFDSMDWDKLFNAESVPLALKSLTFIRNQKFPFHHKEQQFLKDLLSASPYLEYLEASYQSDLVAAIKKYKINLRSLIIIDEGVSNTVKDLAFLPQSLTTLIVKPCNPASTILCPYLFPTNVRMESLINLELFLYLRLSQNDIDNVVKFLTSCYKLKKLVLHDSLALAPHFFEIFASLPELEHLEIPDNVALQNKHAIHITDCCPNLKYVNFSNSISLDGSGFIAVLRGLKELKRIDIINCDSVSRDAIDWARSKGMQVTVASSLPNSQPLGTKKIRLI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of POF3_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of POF3_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of POF3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of POF3_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MPIP_SCHPOcdc25genetic
11809834
RAD1_SCHPOrad1genetic
11809834
RAD3_SCHPOrad3genetic
11809834
RAD17_SCHPOrad17genetic
11809834
RAD26_SCHPOrad26genetic
11809834
CHK1_SCHPOchk1genetic
11809834
RHP9_SCHPOcrb2genetic
11809834
CDS1_SCHPOcds1genetic
11809834
MCL1_SCHPOmcl1genetic
16997270
CUL1_SCHPOcul1physical
11809834
MCL1_SCHPOmcl1physical
16997270
SKP1_SCHPOskp1physical
16997270
RAD3_SCHPOrad3genetic
18931302
RAD26_SCHPOrad26genetic
18931302
SET1_SCHPOset1genetic
18931302
CDS1_SCHPOcds1genetic
18931302
H2AZ_SCHPOpht1genetic
18931302
RAD18_SCHPOrhp18genetic
18931302
KLP6_SCHPOklp6genetic
18931302
RSC4_SCHPOrsc4genetic
18931302
SLM9_SCHPOslm9genetic
18931302
HIR1_SCHPOhip1genetic
18931302
PAN3_SCHPOppk26genetic
18931302
FBH1_SCHPOfbh1genetic
18931302
YHHB_SCHPOhmo1genetic
18931302
CSN1_SCHPOcsn1genetic
18931302
ASK1_SCHPOask1genetic
18931302
SWI10_SCHPOswi10genetic
18931302
RHP9_SCHPOcrb2genetic
18931302
PLMT_SCHPOcho1genetic
18931302
RAD14_SCHPOrhp14genetic
18931302
PMP3_SCHPOpmp3genetic
18931302
CTF18_SCHPOctf18genetic
18931302
VPS72_SCHPOswc2genetic
18931302
CSN5_SCHPOcsn5genetic
18931302
SWI6_SCHPOswi6genetic
18931302
RAD17_SCHPOrad17genetic
18931302
HUS1_SCHPOhus1genetic
18931302
DAD2_SCHPOdad2genetic
18931302
KLP8_SCHPOklp8genetic
18931302
DCC1_SCHPOdcc1genetic
18931302
MMS22_SCHPOmus7genetic
18931302
MRC1_SCHPOmrc1genetic
18931302
CUL1_SCHPOcul1physical
19748355
SKP1_SCHPOskp1physical
19748355
WEE1_SCHPOwee1genetic
11809834
MIK1_SCHPOmik1genetic
11809834
AMS2_SCHPOams2physical
20230746
SKP1_SCHPOskp1physical
20230746
DPOE_SCHPOcdc20physical
23349636
SWI1_SCHPOswi1genetic
23349636
MCL1_SCHPOmcl1physical
26255844

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of POF3_SCHPO

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Related Literatures of Post-Translational Modification

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