FBH1_SCHPO - dbPTM
FBH1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FBH1_SCHPO
UniProt AC Q9USU3
Protein Name F-box DNA helicase protein 1
Gene Name fbh1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 878
Subcellular Localization Cytoplasm. Nucleus. Becomes localized at discrete nuclear foci together with rhp51, in response to DNA strand breakage.
Protein Description Involved in ATP-dependent DNA-unwinding in a 3' to 5' direction, and ATP-ase activities stimulated by the single-stranded DNA-binding protein ssb1. Essential for viability and normal growth of stationary phase cells and in the absence of either srs2 or rqh1 DNA helicase. [PubMed: 16135799]
Protein Sequence MSAQHLHSCKFYRLPLEIIPLICRFLSVQDIQSFIRVFPSFQTILDSSNDLFWKKKNYELRIRRNRLLRGSYAAGVSSSAMNGFVNGTQISSTPAEREYYSKSDEIKNICGLPPGPMKVEQIGHAIDHLVSETHTVDHLGSSIKASFFHIDDVPLEWISSICMQVQSFFSPAAREAISSLKSRTTTSNLLLSLFVGILFEDDLWYFFNTLYMLSSTSAIEFAYFLDSIFTVVRTDYEHYRDPLSQTLITSCTRIHNIVAVIESPYDEPNTKGLTSEQKMIVECQLNPGEVLKVKAFAGTGKTKALLEFAKSRPKDKILYVAFNKAAKEDAELRFPFNVKCSTMHGLAYGAILAQADLPQAKLERQLSNSTIASLLSLQVAFPKANRKNNPGTPSASLVASHIMFTLNRFMHSTDWQLGFRHISKRSLEVTKLSKEKLLAYTKKLWSLIVNFEYTHAPLIPDAYMKLLHLYEFPNIFSKYDYILFDEAQDFTPCMVDLIYRQKHARIVIVGDAHQCIYGFRGANACAFNENLYPSTKQLCLTKSFRFGNSVAKYANFLLSLKGENVKLKGVQNDHAYWSSASNPNNVSGAFRFFPHTIIFRTNKELILQSIRLSVSLPKEIPIAILGSMRKKAFQLLRSGSELAHGQRPSHPKLKDFSSWGEFEVHVKNSAEEDAELALVYDMADELFSESFLSRLDNCEKRLMDSKDDGDNGIILATAHQSKGLEWDNVQLGNDFRPKFDSVSFSRIGSSRYLQEEINILYVALTRAKKRLILNDTITKLYALECGLVRFAGGILTEDQLQPGKVALFVDWQIDKFSFFYETPAEGYNLLVEANEKSVWDIFFGVLSGAWQNYIANTSERLKRSMLFIENQLFAVHDQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of FBH1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FBH1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FBH1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FBH1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RAD55_SCHPOrad55genetic
16135800
SWI5_SCHPOswi5genetic
16135800
SRS2_SCHPOsrs2genetic
16135799
HUS2_SCHPOrqh1genetic
16135799
RAD57_SCHPOrad57genetic
16135799
MSH2_SCHPOmsh2genetic
18931302
RAD3_SCHPOrad3genetic
18931302
NSE6_SCHPOnse6genetic
18931302
DDB1_SCHPOddb1genetic
18931302
RHP41_SCHPOrhp41genetic
18931302
FEN1_SCHPOrad2genetic
18931302
RAD26_SCHPOrad26genetic
18931302
SRS2_SCHPOsrs2genetic
18931302
SWI3_SCHPOswi3genetic
18931302
ATF1_SCHPOatf1physical
19836238
FEN1_SCHPOrad2genetic
16135799
HUS2_SCHPOrqh1genetic
16135800
SPO11_SCHPOrec12genetic
21149262
RTI1_SCHPOrti1genetic
21149262
RAD22_SCHPOrad52genetic
21149262
WAPL_SCHPOwpl1genetic
18818364
CLR3_SCHPOclr3genetic
18818364
AAKB_SCHPOamk2genetic
18818364
KU80_SCHPOpku80genetic
18818364
SNF8_SCHPOdot2genetic
18818364
DHSD_SCHPOsdh4genetic
18818364
RPA12_SCHPOrpa12genetic
18818364
SKI3_SCHPOSPCC1919.05genetic
18818364
YCO6_SCHPOnap1genetic
18818364
SET9_SCHPOset9genetic
18818364
SKI2_SCHPOSPCC550.03cgenetic
18818364
H2A1_SCHPOhta1genetic
18818364
RAD57_SCHPOrad57genetic
25165823
SWI5_SCHPOswi5genetic
25165823
SKP1_SCHPOskp1physical
25165823
UBC4_SCHPOubc4physical
25165823
UBC15_SCHPOubc15physical
25165823
RAD3_SCHPOrad3genetic
22292001

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FBH1_SCHPO

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Related Literatures of Post-Translational Modification

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