dbPTM

SPO11_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SPO11_SCHPO
UniProt AC	P40384
Protein Name	Meiotic recombination protein rec12 {ECO:0000303\|PubMed:8005432}
Gene Name	rec12 {ECO:0000303\|PubMed:8005432}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	345
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Required for formation of the double-strand breaks (DSBs) that initiate meiotic recombination. [PubMed: 10882124 Required for crossover recombination and chiasmatic segregation of chromosomes during meiosis I. Also involved in the faithful equational segregation of chromosomes during meiosis II]
Protein Sequence	MNSNDKKKVVRSWIEQFVHDFVEQLSKPTKDSVNVALKRRKHNSWNGSLDSKANERQKVKVFSFPRNETTIAQLFRVLDCVHEAVISDTVITKRDIYYRDVDLFKRQTVVDELLGDISNTIGCSRSDLNVEASAKGLVFGSIHIALENGTVITATKPLLISHHRISSITSTAKWVLVIEKEAVFQTLTEEALADTIIVTAKGFPDLMTRKFLVKLAKALPDAKFFGIFDWDPHGLCIYSCFKYGSNAYSHEPHSQLRNLQLLGPLYEDIFNKNQEFSLKLNKRDIKMITTLLQFEGFQKEPVVREQLQRMLFIQKKAEIQAILEFPSWIKGKLADADKSGKHSVR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of SPO11_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SPO11_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SPO11_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SPO11_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NSE1_SCHPO	nse1	genetic	15331764
CDS1_SCHPO	cds1	genetic	15689488
CHK1_SCHPO	chk1	genetic	15689488
RAD3_SCHPO	rad3	genetic	15689488
DYHC_SCHPO	dhc1	genetic	15802518
DYLT_SCHPO	dlc1	genetic	15802518
RAD50_SCHPO	rad50	genetic	15654094
RAD32_SCHPO	mre11	genetic	15654094
FEN1_SCHPO	rad2	genetic	16118186
MOA1_SCHPO	moa1	genetic	19370027
DCC1_SCHPO	dcc1	genetic	19370027
CTF18_SCHPO	ctf18	genetic	19370027
PDS5_SCHPO	pds5	genetic	19370027
REC14_SCHPO	rec14	physical	20364342
SGO1_SCHPO	sgo1	genetic	21423721
MAD2_SCHPO	mad2	genetic	21423721
MED20_SCHPO	med20	genetic	18818364
EME1_SCHPO	eme1	genetic	18818364
MUB1_SCHPO	SPBC31F10.10c	genetic	18818364
SERB_SCHPO	ser2	genetic	18818364
REC14_SCHPO	rec14	physical	22841486
PUB1_SCHPO	pub1	genetic	22681890
GPD1_SCHPO	gpd1	genetic	22681890
DEP1_SCHPO	dep1	genetic	22681890
YF48_SCHPO	SPAC3H5.08c	genetic	22681890
GIT3_SCHPO	git3	genetic	22681890
HMT2_SCHPO	hmt2	genetic	22681890
YJFB_SCHPO	SPCC306.11	genetic	22681890
CORO_SCHPO	crn1	genetic	22681890
YCTB_SCHPO	ent3	genetic	22681890
FKBP4_SCHPO	fkbp39	genetic	22681890
VPS3_SCHPO	vps3	genetic	22681890
SAT1_SCHPO	sat1	genetic	22681890
YGNJ_SCHPO	alb1	genetic	22681890
YKN4_SCHPO	mca1	genetic	22681890
YJ2D_SCHPO	SPCC4B3.13	genetic	22681890
MBO1_SCHPO	mto1	genetic	27611693
BQT1_SCHPO	bqt1	genetic	27611693
SGO1_SCHPO	sgo1	genetic	27611693

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SPO11_SCHPO

Related Literatures of Post-Translational Modification