dbPTM

GPD1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GPD1_SCHPO
UniProt AC	P21696
Protein Name	Glycerol-3-phosphate dehydrogenase [NAD(+)] 1
Gene Name	gpd1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	385
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MSGYGQQGVSAANIDSIRPKKRLSIGVVGSGNWGTAIAKICGENARAHGHHFRSKVRMWVFEEEIEYKGEKRKLTEVFNEAHENVKYLPGIECPPNVIAVPDVREVARRADILVFVVPHQFIERVCDQMVGLIRPGAVGISCIKGVAVSKEGVRLYSEVISEKLGIYCGVLSGANVANEVAREQFCETTIGFNPPNEVDIPREQIAAVFDRPYFSVVSVDDVAGVALGGALKNVVAMAVGFADGLEWGGNTKAAIMRRGLLEMQKFATTFFDSDPRTMVEQSCGIADLVTSCLGGRNNRCAEAFVKTGKSLETLEKELLGGQLLQGAATSKDVHEFLLTKDMVKDFPLFTAVYNISYEDMDPKDLIIVLQPLKEDSENEGGTETE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGYGQQGV ------CCCCCCCCC	40.50	24763107
4	Phosphorylation	----MSGYGQQGVSA ----CCCCCCCCCCC	12.40	19547744
10	Phosphorylation	GYGQQGVSAANIDSI CCCCCCCCCCCCCCC	28.61	28889911
310	Phosphorylation	AFVKTGKSLETLEKE HHHHCCCCHHHHHHH	32.55	28889911
313	Phosphorylation	KTGKSLETLEKELLG HCCCCHHHHHHHHHC	45.57	25720772
376	Phosphorylation	LQPLKEDSENEGGTE EEECCCCCCCCCCCC	43.33	28889911
382	Phosphorylation	DSENEGGTETE---- CCCCCCCCCCC----	51.06	28889911
384	Phosphorylation	ENEGGTETE------ CCCCCCCCC------	47.00	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GPD1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GPD1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GPD1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GPD1_SCHPO	gpd1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GPD1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-376 AND THR-382, ANDMASS SPECTROMETRY.	18257517 [Abstract]