YF48_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YF48_SCHPO
• UniProt AC: Q6LA54
• Protein Name: Uncharacterized WD repeat-containing protein C3H5.08c
• Gene Name: SPAC3H5.08c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 933
• Subcellular Localization: Endoplasmic reticulum . Nucleus .
• Protein Sequence: MNGNLPHIQIQSPKNSLDHLNNGRQATHNFEHGKPGDREEANGHADAHSSSGRSRYLSSDTNLLRDGSSSLDPLSKHIMKRTRSEKTLSFLNPSRASSNTHLSREGTNRSSNVTRTVSGRKSNHGSSLTDTGESDQLSLKSFGAIRQPSQHRSSLFSRMLGSTSHIFGIREDMDNESSEEERDGIPRVEGNAADPFSWIPDGKNVWDSPPKYIRVLSHNKKEKSLDHLFLAQELYCKPTLAATHDRYYEPRATDFPNLAHESSEPSSSRHTADAQSITNASVHLHNSSSPLNRTPSVISDTLAVAITSNSSSNSSNNAIWAMKFSRDGRYLAVGGQDRILRIWAVLDSEHARSVASETCSSDPNNPKLNLKAPVFSEAPIREYAGHTADILDLSWSRNNFLLSSSMDKTARLWHPVRKDCLCCFEHSDFVTSIAFHPKDDRFFLSGSLDCKLRLWSIKEKAVSFWNELPELITAVAFSPDGGLAIAGTFVGLCLFYDTRGLRFRTQMSIRSSRGKNAKGSKVTGIQTRTQMIDNIAGDTEMLVTTNDSRIRIYNLRDKSLELKFKGHANAQSQNRAYFDDDGNYVICGSEDHQVFIWDLPPQHMHKTKKKKHEHFKASVRPITAAVFAPTKTKQLLTLSGDPVYLAAISARRSSVISNASIETGPSLRNLKSLSHSYLPIEIMKGHIIVCGDLDGRIRVFRQDSVFAARKLIEKKNIERKNSETLSNSSFFPQALKAHMNSISSPKRHFSLRHKKNASQITNNENNGNDDIKKGDEPEEEHVGLRKNSTQEKNANLDPNEALKRADMMMLQEGASSMVYYSLTNLDNPGATVNEAAKTAATIEQNEHEIQTSVDPISNVKAILPNADDVSSKNSSTEDQLECLRCGNSLFNVFSRSFVFEGAKFSIVCSHCNRKLLKSGSDDGSETHEMSTLP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	QIQSPKNSLDHLNNG EECCCCCCHHHCCCC	41.10	29996109
56	Phosphorylation	SSSGRSRYLSSDTNL CCCCCHHCCCCCCCH	16.51	29996109
58	Phosphorylation	SGRSRYLSSDTNLLR CCCHHCCCCCCCHHC	19.75	29996109
59	Phosphorylation	GRSRYLSSDTNLLRD CCHHCCCCCCCHHCC	45.95	29996109
61	Phosphorylation	SRYLSSDTNLLRDGS HHCCCCCCCHHCCCC	29.70	29996109
69	Phosphorylation	NLLRDGSSSLDPLSK CHHCCCCCCCCHHHH	40.21	25720772
82	Phosphorylation	SKHIMKRTRSEKTLS HHHHHHHCCCCCCHH	32.78	25720772
84	Phosphorylation	HIMKRTRSEKTLSFL HHHHHCCCCCCHHHC	42.72	25720772
87	Phosphorylation	KRTRSEKTLSFLNPS HHCCCCCCHHHCCCC	24.47	25720772
94	Phosphorylation	TLSFLNPSRASSNTH CHHHCCCCCCCCCCC	39.13	25720772
97	Phosphorylation	FLNPSRASSNTHLSR HCCCCCCCCCCCCCC	24.02	25720772
98	Phosphorylation	LNPSRASSNTHLSRE CCCCCCCCCCCCCCC	44.77	25720772
127	Phosphorylation	RKSNHGSSLTDTGES CCCCCCCCCCCCCCC	39.62	25720772
134	Phosphorylation	SLTDTGESDQLSLKS CCCCCCCCCCEEHHH	31.81	21712547
138	Phosphorylation	TGESDQLSLKSFGAI CCCCCCEEHHHHCCC	28.28	24763107
177	Phosphorylation	REDMDNESSEEERDG ECCCCCCCCHHHHCC	49.67	25720772
178	Phosphorylation	EDMDNESSEEERDGI CCCCCCCCHHHHCCC	42.73	25720772
263	Phosphorylation	PNLAHESSEPSSSRH CCCCCCCCCCCCCCC	51.01	27738172
276	Phosphorylation	RHTADAQSITNASVH CCCCCCHHHHEEEEE	32.85	29996109
278	Phosphorylation	TADAQSITNASVHLH CCCCHHHHEEEEEEC	29.94	25720772
281	Phosphorylation	AQSITNASVHLHNSS CHHHHEEEEEECCCC	16.49	29996109
653	Phosphorylation	AAISARRSSVISNAS EHHHHCCCCHHCCCC	24.33	25720772
654	Phosphorylation	AISARRSSVISNASI HHHHCCCCHHCCCCC	22.97	25720772
657	Phosphorylation	ARRSSVISNASIETG HCCCCHHCCCCCCCC	24.96	25720772
660	Phosphorylation	SSVISNASIETGPSL CCHHCCCCCCCCCCC	25.80	25720772
663	Phosphorylation	ISNASIETGPSLRNL HCCCCCCCCCCCCCH	53.36	25720772
666	Phosphorylation	ASIETGPSLRNLKSL CCCCCCCCCCCHHHC	41.11	25720772
674	Phosphorylation	LRNLKSLSHSYLPIE CCCHHHCCCCCCCCE	19.92	25720772
722	Phosphorylation	KNIERKNSETLSNSS HCCCCCCCCCCCCCC	34.69	28889911
724	Phosphorylation	IERKNSETLSNSSFF CCCCCCCCCCCCCHH	34.99	25720772
726	Phosphorylation	RKNSETLSNSSFFPQ CCCCCCCCCCCHHHH	41.93	24763107
728	Phosphorylation	NSETLSNSSFFPQAL CCCCCCCCCHHHHHH	25.75	24763107
729	Phosphorylation	SETLSNSSFFPQALK CCCCCCCCHHHHHHH	34.85	21712547
741	Phosphorylation	ALKAHMNSISSPKRH HHHHHHHHCCCCCHH	19.10	24763107
743	Phosphorylation	KAHMNSISSPKRHFS HHHHHHCCCCCHHHC	40.17	21712547
744	Phosphorylation	AHMNSISSPKRHFSL HHHHHCCCCCHHHCC	32.54	24763107
758	Phosphorylation	LRHKKNASQITNNEN CCCCCCHHHHCCCCC	31.35	25720772
761	Phosphorylation	KKNASQITNNENNGN CCCHHHHCCCCCCCC	25.10	21712547
788	Phosphorylation	HVGLRKNSTQEKNAN HCCCCCCCHHHHHCC	34.21	25720772
789	Phosphorylation	VGLRKNSTQEKNANL CCCCCCCHHHHHCCC	50.57	25720772
870	Phosphorylation	LPNADDVSSKNSSTE CCCCHHCCCCCCCHH	42.46	21712547
871	Phosphorylation	PNADDVSSKNSSTED CCCHHCCCCCCCHHH	35.39	21712547
874	Phosphorylation	DDVSSKNSSTEDQLE HHCCCCCCCHHHHHH	42.23	25720772
875	Phosphorylation	DVSSKNSSTEDQLEC HCCCCCCCHHHHHHH	45.25	25720772
876	Phosphorylation	VSSKNSSTEDQLECL CCCCCCCHHHHHHHH	43.32	25720772
896	Phosphorylation	LFNVFSRSFVFEGAK HHHHHHHHHHCCCCC	25.27	25720772
918	Phosphorylation	CNRKLLKSGSDDGSE CCCHHHHCCCCCCCC	43.42	21712547
920	Phosphorylation	RKLLKSGSDDGSETH CHHHHCCCCCCCCCC	39.35	24763107
924	Phosphorylation	KSGSDDGSETHEMST HCCCCCCCCCCCCCC	46.44	24763107
926	Phosphorylation	GSDDGSETHEMSTLP CCCCCCCCCCCCCCC	25.49	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YF48_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YF48_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YF48_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YF48_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-722, AND MASSSPECTROMETRY.
PubMed: 18257517