RAD50_SCHPO - dbPTM
RAD50_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAD50_SCHPO
UniProt AC Q9UTJ8
Protein Name DNA repair protein rad50
Gene Name rad50
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1285
Subcellular Localization Nucleus . Chromosome .
Protein Description Involved in DNA double-strand break (DSB) repair. Involved in mating type switching and has a role in choosing the sister chromatid for recombinational repair. Also has a role in telomere length maintenance..
Protein Sequence MSCIDRMSIMGIRSFDNRSRESIQFFSPLTLIVGQNGSGKTTIIECLKYATTGILPPNTKGGAFIHDPKICGEKEVLAQVKLAFRNTNQVKMICTRSLQLSVKKTTRQQKTLDGQLLILKDNERTTISNRCAELDSQVPLSLGVSKALLDYVIFCHQEESFWPLSEPANLKKRFDEIFESLRYAKALDQIKGLKRDQETQVKVDQATLTHYRSDKERAEKIELRVHESLKRISCIRSKVEELDQEITETARLQDELFKSTEEYEQQMITIRHLESQSDIINTTINDLKSQMTITDESSEDLEKLHSNFAEKVKEEQELYKSLEKKRSDLESLLKSRRELLEKLTGDLGKIQGEIESLEKLKVKKSTMINEIVHRYNINEINEEGIMTEVSKYASLVNKNYEISSGKLKERQVAVRARIEGIKAHEMFLNNRVSEINSSLEKQLTTQKELRSRFEILFPVKLQREDFTKDVEKSDLWIKSLRQEYESKNLLELLDKHQTALSSVENRLDEISEIVDSYHKYSGVRTKLQVFEENKTNKSAILANQLMTLKSSFSEVMSYELKDDDNYNEELDKLVEDVRKKLQEKEEAESSLRSVRERLEIRISLSVQSINDLTENKKIKTKTLKSYSGTFASMISEIKALESEIEENRKTLHSLQFGSTFYEKAIEICVDQHACQLCQRSLDKEEEKLFVEHCHSMIDVIPSKSAEVYSHLETLTKTFKNLSEAKPIFDEIELLDKRLSETKTELSDLQGDLQGLDIRKDEIQSELDTLYLRRANLEKLQLLVKDISNLEEEIRTIDRETEVLRIELPSSIAHHNLDEIYAEREKLLEKRGYLRKQIERTKLEETSFKKKIDDAVLANNEQKLKLTKLNFQVNELEQLEKDINKSSEDCDLQKKKLLEVSSKQGSQAPFLNELESEYEKLEADIQEMAQKSRTEILEANEYLHQLNEWNSELRIDVSTKFKCIKEKKSNIGEEVRIIASKIESTDDNLRKLQERLADLRTRERNASDNLRLRALMRQLEEAVTQKNYLLSQQSHDDRESFRERMQILKSKYGALNAERAGLLGECKQLENSITKDKEELNMEFKDADERFRRQLIKTKTTGKANEDLGKYAKALDVAIMQLHSMKMNEINRIVDELWKQTYCGTDIDTILIRSDSEGKGNRTYNYRVCMVKGDAELDMRGRCSAGQKVLACIIIRLALAECLGVNCGILALDEPTTNLDEENICSLAKNLSRIVEFRRKQANFQLIVITHDEQFIRLVNSDAYCSYYYRVKRDTNQKSMIVKEPL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
327PhosphorylationKSLEKKRSDLESLLK
HHHHHHHHHHHHHHH		56.2625720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAD50_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAD50_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAD50_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KU70_SCHPOpku70genetic
12861005
KU80_SCHPOpku80genetic
12861005
RAD22_SCHPOrad52genetic
11726502
RAD55_SCHPOrad55genetic
11726502
FEN1_SCHPOrad2genetic
11726502
RAD21_SCHPOrad21genetic
11726502
RAD32_SCHPOmre11physical
12861005
PLI1_SCHPOpli1genetic
17209013
SFR1_SCHPOsfr1genetic
18769921
EXO1_SCHPOexo1genetic
18388861
EXO1_SCHPOexo1genetic
12861005
ATL1_SCHPOatl1genetic
22658721
RAD32_SCHPOmre11physical
23080121
TIP20_SCHPOdrp1physical
25269894
SPO11_SCHPOrec12genetic
15238514
TO6BL_SCHPOrec6genetic
15238514
RAD32_SCHPOmre11physical
21441914
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAD50_SCHPO

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Related Literatures of Post-Translational Modification

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