CORO_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CORO_SCHPO
• UniProt AC: O13923
• Protein Name: Coronin-like protein crn1
• Gene Name: crn1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 601
• Protein Sequence: MSGRFVRASKYRHIFGQTCKKELCYDNIKLSNNAWDSNLLSVNPFYLSVNWNAGAGGALAVIPLNERGKLPDQVNLFRGHTAAVLDTDWNPFHDQVLASGGDDSKIMIWKVPEDYTVMEPYEDVHPIAELKGHSRKVGLVQYHPTAANVLASSSADNTIKLWDCEKGVAHVSLKMDVMCQSMSFNADGTRLVTTSRDKKVRVWDPRTDKPVSVGNGHAGAKNPRVVWLGSLDRFATTGFSKMSDRQIALWDPTNLSEPIGGFTTLDTGSGILMPFWDDGTKVIYLAGKGDGNIRYYEYENDVFHYLSEFKSVDPQRGIAFLPKRGVNVSENEVMRAYKSVNDSIIEPISFIVPRRSESFQSDIYPPAPSGKPSLTAEEWASGKDAQPDLLDMSTLYESKGTVEKAVSATVPSAGAQVQKHNEEKVETPKPEAQPVSKPKESAEEQKPSKEPEVKPTTPSASKVEEPSKKRDEDNHQKEETVTQPKREKTPVEKSFPKPASSPVTFSEDVKKEPSEEKKLEVSDEAPKAAPLAESKKVEEKEPFYVSKDKKDISAVNLADLNKRFEGFEKRYEEELAIRDWKIAQLEDKLAKLTEAIKEKCN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
115	Phosphorylation	IWKVPEDYTVMEPYE EEECCCCCEECCCCC	10.28	25720772
116	Phosphorylation	WKVPEDYTVMEPYED EECCCCCEECCCCCC	26.21	25720772
343	Phosphorylation	AYKSVNDSIIEPISF HHHCCCCCCCCEEEE	21.91	25720772
427	Phosphorylation	HNEEKVETPKPEAQP CCHHCCCCCCCCCCC	39.33	28889911
457	Phosphorylation	EPEVKPTTPSASKVE CCCCCCCCCCHHHCC	24.63	28889911
494	Phosphorylation	EKTPVEKSFPKPASS CCCCCHHCCCCCCCC	33.02	28889911
500	Phosphorylation	KSFPKPASSPVTFSE HCCCCCCCCCCCCCH	43.64	28889911
501	Phosphorylation	SFPKPASSPVTFSED CCCCCCCCCCCCCHH	26.04	28889911
504	Phosphorylation	KPASSPVTFSEDVKK CCCCCCCCCCHHHCC	25.48	24763107
553	Phosphorylation	SKDKKDISAVNLADL CCCHHHCCCCCHHHH	35.98	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CORO_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CORO_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CORO_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EHS1_SCHPO	yam8	genetic	18931302
CAPZA_SCHPO	acp1	genetic	18931302
YAI8_SCHPO	SPAC24B11.08c	genetic	18818364
EME1_SCHPO	eme1	genetic	18818364
UFD2_SCHPO	ufd2	genetic	22681890
CAPZA_SCHPO	acp1	genetic	22681890
CAPZB_SCHPO	acp2	genetic	22681890
GMA12_SCHPO	gma12	genetic	22681890
CTK3_SCHPO	lsg1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-500; SER-501 ANDSER-553, AND MASS SPECTROMETRY.
PubMed: 18257517