CAPZB_SCHPO - dbPTM
CAPZB_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAPZB_SCHPO
UniProt AC Q9HGP5
Protein Name F-actin-capping protein subunit beta
Gene Name acp2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 268
Subcellular Localization Cytoplasm, cytoskeleton . Nucleus . Septum. Localizes to cell tips during interphase.
Protein Description F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Competes with formin cdc12 for attachment to the actin filaments barbed ends. Slowly replaces cdc12 on the barbed ends in preparation for filament disassembly during contractile ring constriction..
Protein Sequence MNSEDAALDLLRRLNPKDISKNLDTILSVAPDLADVLLSSVDQPLKVNTCSESGNQYLLCDFNRDGDSYRSPWSNKYDPPLEDGLVSTDRVRKLEVSLNEAIRVYLDLYYEGGVSSVYLWDQDDSYAGAVLIKKASTSNSSGWDSIHVFECLPTTETNVYDYRLTSTIILFLSSGSEEQSALPSKALNLSGHLTRQTSQRLPAADDDTEIANVGKLVEEMETRMRNFLQDVYFGKTKDIINQTRSIQPVSDAQPNDSALRSVLNDLSI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
197PhosphorylationSGHLTRQTSQRLPAA
CCCHHHHHHCCCCCC		24.4427738172
198PhosphorylationGHLTRQTSQRLPAAD
CCHHHHHHCCCCCCC		12.6425720772
245PhosphorylationDIINQTRSIQPVSDA
HHHHCCCCCCCCCCC		29.0325720772
261PhosphorylationPNDSALRSVLNDLSI
CCHHHHHHHHHHCCC		31.6321712547
267PhosphorylationRSVLNDLSI------
HHHHHHCCC------		29.1724763107
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAPZB_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAPZB_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAPZB_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
COFI_SCHPOadf1genetic
16866873
COFI_SCHPOadf1genetic
16467379
PROF_SCHPOcdc3genetic
16866873
AIN1_SCHPOain1genetic
16866873
MLR4_SCHPOcdc4genetic
16866873
RNG2_SCHPOrng2genetic
16866873
CAPZA_SCHPOacp1physical
16866873
CORO_SCHPOcrn1genetic
18931302
FIMB_SCHPOfim1genetic
16866873
FIMB_SCHPOfim1genetic
15743909
PROF_SCHPOcdc3genetic
15743909
ACT_SCHPOact1genetic
15743909
AIN1_SCHPOain1genetic
15743909
MLR4_SCHPOcdc4genetic
15743909
CDC15_SCHPOcdc15genetic
15743909
RNG2_SCHPOrng2genetic
15743909
MID1_SCHPOmid1genetic
15743909
TBB_SCHPOnda3genetic
15743909
ARP3_SCHPOarp3genetic
15743909
CDC12_SCHPOcdc12genetic
15743909
MYO2_SCHPOmyo2genetic
15743909
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAPZB_SCHPO

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Related Literatures of Post-Translational Modification

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