dbPTM

MLR4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MLR4_SCHPO
UniProt AC	Q09196
Protein Name	Myosin regulatory light chain cdc4
Gene Name	cdc4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	141
Subcellular Localization	Cytoplasm.
Protein Description	Involved in cytokinesis. Required for the formation and function of the contractile ring..
Protein Sequence	MSTDDSPYKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPVKDGMVNYHDFVQMILAN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
2	Phosphorylation	------MSTDDSPYK ------CCCCCCHHH	40.31	28889911
6	Phosphorylation	--MSTDDSPYKQAFS --CCCCCCHHHHHHH	32.70	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MLR4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MLR4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MLR4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYO2_SCHPO	myo2	genetic	10769212
IMP2_SCHPO	imp2	genetic	9786952
HSP9_SCHPO	hsp9	genetic	8654972
ACT_SCHPO	act1	genetic	10371213
MYO2_SCHPO	myo2	physical	10769212
MYO3_SCHPO	myp2	physical	10769212
MYO2_SCHPO	myo2	physical	11942609
MYO2_SCHPO	myo2	physical	11087749
MYO2_SCHPO	myo2	physical	10022828
MYO3_SCHPO	myp2	genetic	20739711
SPN1_SCHPO	spn1	genetic	20739711
MID1_SCHPO	mid1	physical	21422229
MYO2_SCHPO	myo2	physical	21422229
CAM2_SCHPO	cam2	genetic	21693583
PIK1_SCHPO	pik1	physical	21693583
MYO2_SCHPO	myo2	physical	21693583
MID1_SCHPO	mid1	physical	22427686
KIN1_SCHPO	kin1	genetic	23294323
RNG2_SCHPO	rng2	genetic	23615450
SND1_SCHPO	snd1	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MLR4_SCHPO

Related Literatures of Post-Translational Modification