dbPTM

SND1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SND1_SCHPO
UniProt AC	Q9Y7U7
Protein Name	Staphylococcal nuclease domain-containing protein 1
Gene Name	snd1 {ECO:0000312\|EMBL:CAB39904.1}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	878
Subcellular Localization	Cytoplasm, cytosol .
Protein Description
Protein Sequence	MSQYVSSMIKYAQSGDSFNILIKDNAKKITEKQFSLAYVECPRFRREGDEPFAFEAQEFSRRLVVGRPASVSTLYVIPTSKREYGRIRTSEFDLAESLLREGLAKLRPEATRNEGTSENSYFVSLEEAQDHAQQYKLGIWGPSDDVVVTEKANPANPAKFLKAHKGKKLNGIVETIRNGDQVRVRLFLSPKQHQLVTISLAGVRCPRSTFTATSPEQTSSEQEPCGDEAKQFVVTRLLQRNVVIELLDLAPNGVSFLGNVLHPAGNIATFLLSSGLGRVADNHISALGPETMQSLRTIERKAKISRLGIWKNISVSIPDINSLSLKDYSAVVSRVISTDTLEVRKDNGVECRIQLSSIRHPRPSNEKEAPYQLEAREFLRKKIIGKRVQVSLDFIRPGQNDLPAINNCTVKLSDGTNVALMVVKSGYATVIRYRMDSVDRSPIYDFLIEAEKAAQEGRKGMWSGKKPAYENIVNASESSLRSRQYLSSLQRTRKLSVIIENVISGSRFRCFCPKENCYFMFACAGIRTPRTARNDQEKGEPFAEESLSLAKSLLQHDAQVEILSVDNNGCFLGDIYVNHDTNFALKLLSQGLAWCQGYASQSNVQYSQYHDTEAAAKEQKVGMWHDYVPPEKKAASTEKESENTVKEPIYLDIVLSDIAEDGKFSFQIIGTGIQQLETLMSDLGSLKKSFKPSEKINVGMNVAAISALDNAMYRGRVLRCDRENQAADVLLYDYGSVEQIPFKNISSLPDTYTKLKPQAQLARLSYVQLPPPSSDYYEDARLVFRELAMNKGLVAKVDGHEGNVYSVTLYNPSDGSDFSDCINAQLVALGMASVIPKKKTSHFEKDTASLNILEEHQQEARLNHIGFWVYGDPLEYED

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	EYGRIRTSEFDLAES CCCCCCCCCHHHHHH	26.81	25720772
314	Phosphorylation	LGIWKNISVSIPDIN HCCCCCEEEECCCCC	21.14	29996109
316	Phosphorylation	IWKNISVSIPDINSL CCCCEEEECCCCCCC	22.93	28889911
496	Phosphorylation	LQRTRKLSVIIENVI HHHHHCHHHHEEECC	17.82	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SND1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SND1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SND1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SND1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SND1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-316, AND MASSSPECTROMETRY.	18257517 [Abstract]