| UniProt ID | FIMB_SCHPO | |
|---|---|---|
| UniProt AC | O59945 | |
| Protein Name | Fimbrin | |
| Gene Name | fim1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 614 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, actin patch . Localizes both to the cortical actin patches and to the medial ring in an F-actin-dependent manner. | |
| Protein Description | Binds to actin, and functionally associates with actin structures involved in the development and maintenance of cell polarity. Plays a role in cytokinesis. Plays important roles in mating and in spore formation.. | |
| Protein Sequence | MLALKLQKKYPELTNEEILTLTDQFNKLDVDGKGYLDQPTTIKAFEDSKKGSYDEVREAIREVNVDSSGRVEPEDFVGIFNVLKKGVEGTEVKKGRITIKGSSSSVSHTINEEERREFIKHINSVLAGDPDVGSRVPINTETFEFFDQCKDGLILSKLINDSVPDTIDERVLNKQRNNKPLDNFKCIENNNVVINSAKAMGGISITNIGAGDILEGREHLILGLVWQIIRRGLLGKIDITLHPELYRLLEEDETLDQFLRLPPEKILLRWFNYHLKAANWPRTVSNFSKDVSDGENYTVLLNQLAPELCSRAPLQTTDVLQRAEQVLQNAEKLDCRKYLTPTAMVAGNPKLNLAFVAHLFNTHPGLEPLNEEEKPEIEPFDAEGEREARVFTLWLNSLDVTPSIHDFFNNLRDGLILLQAYDKITPNTVNWKKVNKAPASGDEMMRFKAVENCNYAVDLGKNQGFSLVGIQGADITDGSRTLTLALVWQMMRMNITKTLHSLSRGGKTLSDSDMVAWANSMAAKGGKGSQIRSFRDPSISTGVFVLDVLHGIKSEYVDYNLVTDGSTEELAIQNARLAISIARKLGAVIFILPEDIVAVRPRLVLHFIGSLMAV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 102 | Phosphorylation | GRITIKGSSSSVSHT CCEEEECCCCCCCCC | 23.26 | 29996109 | |
| 103 | Phosphorylation | RITIKGSSSSVSHTI CEEEECCCCCCCCCC | 34.99 | 29996109 | |
| 104 | Phosphorylation | ITIKGSSSSVSHTIN EEEECCCCCCCCCCC | 36.13 | 29996109 | |
| 105 | Phosphorylation | TIKGSSSSVSHTINE EEECCCCCCCCCCCH | 29.59 | 29996109 | |
| 107 | Phosphorylation | KGSSSSVSHTINEEE ECCCCCCCCCCCHHH | 19.50 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FIMB_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FIMB_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FIMB_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CAPZA_SCHPO | acp1 | genetic | 11694585 | |
| CAPZA_SCHPO | acp1 | physical | 11694585 | |
| ACT_SCHPO | act1 | physical | 11694585 | |
| CDC15_SCHPO | cdc15 | genetic | 11694585 | |
| RNG2_SCHPO | rng2 | genetic | 11694585 | |
| TPM_SCHPO | cdc8 | genetic | 20705471 | |
| ACT_SCHPO | act1 | physical | 20705466 | |
| TPM_SCHPO | cdc8 | genetic | 20705466 | |
| COFI_SCHPO | adf1 | genetic | 20705466 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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