dbPTM

AIN1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AIN1_SCHPO
UniProt AC	O13728
Protein Name	Alpha-actinin-like protein 1
Gene Name	ain1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	621
Subcellular Localization	Cytoplasm, cytoskeleton . Localizes to the medial ring in an F-actin-dependent manner.
Protein Description	Binds to actin and is involved in actin-ring formation and organization. Plays a role in cytokinesis and is involved in septation..
Protein Sequence	MQANQWQSVQNRTFTKWFNTKLSSRDLPSVFDLRKDLSDGILLIQLLEIIGDENLGRYNRNPRMRVHRLENVNKALEYIKSKGMPLTNIGPADIVDGNLKLILGLIWTLILRFTIADINEEGLTAKEGLLLWCQRKTANYHPEVDVQDFTRSWTNGLAFCALIHQHRPDLLDYNKLDKKNHRANMQLAFDIAQKSIGIPRLIEVEDVCDVDRPDERSIMTYVAEYFHAFSTLDKVETAARRVERFTEVLMSTHDMKIDYESRMKRLLGSIARMQEYWHTVQFENNYTDVKSHSNNFAKFKATEKREWVKEKIDLESLLGTIQTNLKTYQLRKYEPPAGLKIVDLERQWKDFLSEEANQSKLINTHMREIKESMRIAFADRANSFSKMLSTISNEITNLQGDWRDQLDHVEFLQEHLGPLEVELASVKVLYDNCFQAGIEENDYTMFSYEDLEHEFGITANIIANKIKYLENELLEREKRTLSKQELDGITKVFRHFEKKKSNMLNEVEFYAALASLGLVYDTEEGTALFHRAANSEEGVTYERFTEIVMEELEDRDSARQVLYAFCDVADGKSYVTSDDLLRSQVRPNIVKFLECNMNKHSEGLDYLTWIKQLLAEDKEIV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
316	Phosphorylation	KEKIDLESLLGTIQT HHHCCHHHHHHHHHH	35.87	25720772
320	Phosphorylation	DLESLLGTIQTNLKT CHHHHHHHHHHHHHH	15.19	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AIN1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AIN1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AIN1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ACT_SCHPO	act1	genetic	11294907
MYO2_SCHPO	myo2	genetic	11294907
PROF_SCHPO	cdc3	genetic	11294907
RNG2_SCHPO	rng2	genetic	11294907
FIMB_SCHPO	fim1	genetic	11294907
FIMB_SCHPO	fim1	genetic	22740629
CDC7_SCHPO	cdc7	genetic	22740629
CDC11_SCHPO	cdc11	genetic	22740629
CDC15_SCHPO	cdc15	genetic	22740629
ACT_SCHPO	act1	physical	27075176

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AIN1_SCHPO

Related Literatures of Post-Translational Modification