CDC7_SCHPO - dbPTM
CDC7_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CDC7_SCHPO
UniProt AC P41892
Protein Name Cell division control protein 7
Gene Name cdc7
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1062
Subcellular Localization
Protein Description Protein kinase essential for cell division. Plays a key role in initiation of septum formation and cytokinesis..
Protein Sequence MHNIQASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTNDSLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDHSVVGSPYWMAPEVIELVGATTASDIWSVGCTVIELLDGNPPYYDLDPTSALFRMVKDEHPPLPSNISSAAKSFLMQCFQKDPNLRIKTRKLLKHPWVIMNQTSSKFSDAIDEVQKYNERVKESTLTAIIEPTSNRINPTLHSGRQSSYHMPESPKTPIAESPDHDNWDNEFQGTLKISDDVLKKSEHFMDFCSNFKGKNNSSSITSSPSKSRHAFNSDQISESNNFNASPLSTPLKAQFDPSKPALNRSIDHQKTPQHKRYLSTEFKENIPDGIEKFVETPRDSEFTDIFPTSSIKVQGLRKETGLGTLVLNKCYGSWNNEENEDGEESDIFDSIETNLENLDIENNIALDKRTHLASLLSSLLGSLRDKNIGSKDTTVSQIASILSEDLSLKREIIQAHGILPLLETLREIKTPDVQLLLLKLINTVAFDDHTTLQKVCFAGGLPLMLSFSNREHSFEFRYESAIFIQQMYRTSALTLQMFLSSNGLNSLLLFIKEDYGTNRDFVFVGVEGIWKLLRQQDYIPKNDICTMVVNDSLEPLTKAMLKALATDDDSSRMSLTRICEILLALSQADNYVKESLLCESALRRILRILLYLPHSDMAITLQFFKQLSMVPSSLSLLRKVHIIPLLTHILGDSKIEKGRKEIRSEALAALFNVCKLDKKSQEEAVISGAIPLLQEVIIKDRLFKEFALPILLALPQAGPVSRIYLWQNKCLDFFLSLLSDLNWQSAVFDTIASWLQFELREVQRVLAEKRNVQLVLKVFCISQSASSNRMLDTLGRVCQISPRLAASYGQPIIFQKFKEKLTHKGTKPIVVLNIFQIMKSMCEASSQSVAYIAHCGLPDVVANLNQTSDSVLVKELAKDLLKYLKVPQGPINEHKSPISKPHMPPPRWQPKQPLTQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MHNIQASSITLGDC
-CCCCCCCCEEHHHH		13.0921712547
8PhosphorylationMHNIQASSITLGDCL
CCCCCCCCEEHHHHC		23.7021712547
323PhosphorylationPKTPIAESPDHDNWD
CCCCCCCCCCCCCCC		26.9728889911
336PhosphorylationWDNEFQGTLKISDDV
CCCCCCCEEECCHHH		17.6929996109
365PhosphorylationKGKNNSSSITSSPSK
CCCCCCCCCCCCCCC		29.7021712547
369PhosphorylationNSSSITSSPSKSRHA
CCCCCCCCCCCCCCC		25.2521712547
373PhosphorylationITSSPSKSRHAFNSD
CCCCCCCCCCCCCHH		33.3721712547
391PhosphorylationESNNFNASPLSTPLK
CCCCCCCCCCCCCCH		27.7221712547
394PhosphorylationNFNASPLSTPLKAQF
CCCCCCCCCCCHHHC		31.2221712547
395PhosphorylationFNASPLSTPLKAQFD
CCCCCCCCCCHHHCC		40.0821712547
417PhosphorylationRSIDHQKTPQHKRYL
CCCCCCCCHHHHHHC		22.9329996109
425PhosphorylationPQHKRYLSTEFKENI
HHHHHHCCHHHHHHC		19.5629996109
426PhosphorylationQHKRYLSTEFKENIP
HHHHHCCHHHHHHCC		42.7325720772
455PhosphorylationFTDIFPTSSIKVQGL
CCCCCCCCCCEECCC		30.2424763107
456PhosphorylationTDIFPTSSIKVQGLR
CCCCCCCCCEECCCC		28.9825720772
1042PhosphorylationGPINEHKSPISKPHM
CCCCCCCCCCCCCCC		29.4021712547
1045PhosphorylationNEHKSPISKPHMPPP
CCCCCCCCCCCCCCC		43.4421712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CDC7_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CDC7_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CDC7_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPG1_SCHPOspg1genetic
10924454
SCE3_SCHPOsce3genetic
10924454
RHO1_SCHPOrho1genetic
10924454
TPM_SCHPOcdc8genetic
10924454
SID2_SCHPOsid2genetic
9649519
SPG1_SCHPOspg1genetic
9649519
SCW1_SCHPOscw1genetic
12796296
2AD1_SCHPOpar1genetic
11707284
ZFS1_SCHPOzfs1genetic
10462526
CDC11_SCHPOcdc11genetic
8039497
SCW1_SCHPOscw1genetic
12242222
PP2B_SCHPOppb1genetic
12354095
CDC11_SCHPOcdc11physical
16787941
SPG1_SCHPOspg1physical
16469735
CDC7_SCHPOcdc7physical
16469735
SID4_SCHPOsid4physical
10805785
CDC11_SCHPOcdc11physical
11676915
SPG1_SCHPOspg1physical
9420333
CDC14_SCHPOcdc14genetic
1527180
CDC16_SCHPOcdc16genetic
1527180
CDC37_SCHPOcdc37genetic
17496123
CDC15_SCHPOcdc15genetic
1527180
ACE2_SCHPOace2genetic
16415366
ORB6_SCHPOorb6genetic
20805322
CDC11_SCHPOcdc11genetic
22419817
CDC11_SCHPOcdc11physical
22419817
PP2A2_SCHPOppa2genetic
22267499
PTPA2_SCHPOypa2genetic
22267499
CDC16_SCHPOcdc16genetic
10924454
MOB1_SCHPOmob1genetic
10769201
MTO1_SCHPOSPBC30B4.06cgenetic
22681890
MCL1_SCHPOmcl1genetic
22681890
SPG1_SCHPOspg1genetic
9203579
PLO1_SCHPOplo1genetic
10924454
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CDC7_SCHPO

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Related Literatures of Post-Translational Modification

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