dbPTM

PP2A2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PP2A2_SCHPO
UniProt AC	P23636
Protein Name	Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit
Gene Name	ppa2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	322
Subcellular Localization
Protein Description	Essential role in cell cycle control. PP2A may be involved in controlling the entry into mitosis, possibly acting as an inhibitor..
Protein Sequence	MSIDPANDSKLAPEANDATLGDVDRWIEQLKKCEPLSEADVEMLCDKAREVLCQENNVQPVRNPVTVCGDIHGQFHDLMELFKIGGDVPDMNYLFMGDYVDRGYHSVETVSLLVAMKLRYPNRITILRGNHESRQITQVYGFYDECLRKYGSANVWKHFTNLFDYFPLTALIEDRIFCLHGGLSPSIDSLDHVRTLDRVQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISETFNHANGLSLTARAHQLVMEGFNWAHDGDVVTIFSAPNYCYRCGNQAAILEVDDTMNQVFLQFDPAPREGEPVIARRTPDYFL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
322	Methylation	RRTPDYFL------- ECCCCCCC-------	5.81	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PP2A2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PP2A2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PP2A2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WEE1_SCHPO	wee1	genetic	8389306
TIP41_SCHPO	tip41	genetic	16297994
2AD2_SCHPO	par2	physical	11380623
PTPA2_SCHPO	ypa2	genetic	22267499
PTPA1_SCHPO	ypa1	genetic	22267499
2AD1_SCHPO	par1	genetic	22267499
2ABA_SCHPO	pab1	genetic	22267499
YD44_SCHPO	ppa3	genetic	22119525
COX19_SCHPO	SPCC1672.04c	genetic	22681890
TPP1_SCHPO	tpp1	genetic	22681890
NSE6_SCHPO	nse6	genetic	22681890
HRP3_SCHPO	hrp3	genetic	22681890
FLP1_SCHPO	clp1	genetic	22681890
PCK1_SCHPO	pck1	genetic	22681890
REB1_SCHPO	reb1	genetic	22681890
ALG12_SCHPO	alg12	genetic	22681890
YHG6_SCHPO	SPBC1198.06c	genetic	22681890
BQT4_SCHPO	bqt4	genetic	22681890
YNU4_SCHPO	SPBC28E12.04	genetic	22681890
AGM2_SCHPO	SPAC1296.01c	genetic	22681890
MU122_SCHPO	mug122	genetic	22681890
PDX1_SCHPO	snz1	genetic	22681890
MAK3_SCHPO	mak3	genetic	22681890
SWD3_SCHPO	swd3	genetic	22681890
MGR2_SCHPO	mgr2	genetic	22681890
MU178_SCHPO	mug178	genetic	22681890
EXO5_SCHPO	exo5	genetic	22681890
BST1_SCHPO	bst1	genetic	22681890
SPP1_SCHPO	spf1	genetic	22681890
AATC_SCHPO	SPAC10F6.13c	genetic	22681890
YGWH_SCHPO	gmh4	genetic	22681890
MAC1_SCHPO	mac1	genetic	22681890
MUG80_SCHPO	mug80	genetic	22681890
POM1_SCHPO	pom1	genetic	22681890
PAN3_SCHPO	ppk26	genetic	22681890
FCF2_SCHPO	fcf2	genetic	22681890
ASH2_SCHPO	ash2	genetic	22681890
CHR3_SCHPO	cfh1	genetic	22681890
IF5A2_SCHPO	tif512	genetic	22681890
ZFS1_SCHPO	zfs1	genetic	22681890
YEEB_SCHPO	SPAC19A8.11c	genetic	22681890
SCS7_SCHPO	scs7	genetic	22681890
PMP1_SCHPO	pmp1	genetic	22681890
ALG5_SCHPO	alg5	genetic	22681890
YF75_SCHPO	spa2	genetic	22681890
YIDH_SCHPO	SPAC227.17c	genetic	22681890
YLP3_SCHPO	red1	genetic	22681890
NACB_SCHPO	btf3	genetic	22681890
YGVA_SCHPO	def1	genetic	22681890
PDT1_SCHPO	pdt1	genetic	22681890
RL27A_SCHPO	rpl2701	genetic	22681890
SET1_SCHPO	set1	genetic	22681890
SEC14_SCHPO	spo20	genetic	22681890
PTPA1_SCHPO	ypa1	genetic	22681890
CTK3_SCHPO	lsg1	genetic	22681890
TSR4_SCHPO	SPBC25H2.15	genetic	22681890
YBAC_SCHPO	rud3	genetic	22681890
MCP2_SCHPO	mcp2	genetic	22681890
ERD11_SCHPO	erd1	genetic	22681890
PPME1_SCHPO	SPBP4H10.17c	genetic	22681890
BU107_SCHPO	bun107	genetic	22681890
YBW4_SCHPO	SPBC651.04	genetic	22681890
RAP1_SCHPO	rap1	genetic	22681890
RPB9_SCHPO	rpb9	genetic	22681890
2AD2_SCHPO	par2	genetic	22681890
MID1_SCHPO	mid1	genetic	22681890
YJC7_SCHPO	SPCC736.07c	genetic	22681890
PRS10_SCHPO	rpt4	genetic	22681890
SHF1_SCHPO	shf1	genetic	22681890
YFE6_SCHPO	gmh5	genetic	22681890
MCL1_SCHPO	mcl1	genetic	22681890
NAB2_SCHPO	nab2	genetic	22681890
CLR1_SCHPO	clr1	genetic	22681890
YKEE_SCHPO	SPAC1805.14	genetic	22681890
TSC1_SCHPO	tsc1	genetic	22681890
UBP16_SCHPO	ubp16	genetic	22681890
ATC1_SCHPO	pmr1	genetic	22681890
RCD1_SCHPO	rcd1	genetic	22681890
RGA8_SCHPO	rga8	genetic	22681890
TCG1_SCHPO	tcg1	genetic	22681890
ARB2_SCHPO	arb2	genetic	22681890
YQK8_SCHPO	SPCC1494.08c	genetic	22681890
ZFS1_SCHPO	zfs1	genetic	22624651
SNF5_SCHPO	snf5	genetic	22624651
FLP1_SCHPO	clp1	genetic	22624651
YCJ5_SCHPO	tap42	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PP2A2_SCHPO

Related Literatures of Post-Translational Modification