dbPTM

SWD3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SWD3_SCHPO
UniProt AC	O43017
Protein Name	Set1 complex component swd3
Gene Name	swd3 {ECO:0000312\|EMBL:CAA17803.1}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	380
Subcellular Localization	Nucleus .
Protein Description	The Set1 complex specifically methylates 'Lys-4' of histone H3..
Protein Sequence	MDSTAQQFPLNHDLQVQKDQKGVVEEDEEQIHKRIRNYESHSGFSEYCTLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMSWDCYSSKNIPKNTEALPNNDSSYPDDAESFMHDAYLLIPSEDGTIQITDPSTKIIIDDSIRHSDDPETSLLNVTSLGPFIITSGTDPYVRVWAPSLLLSKHEKDGFSP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
379	Phosphorylation	KHEKDGFSP------ CCCCCCCCC------	34.92	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SWD3_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SWD3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SWD3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SET1_SCHPO	set1	physical	14617822
SPP1_SCHPO	spf1	physical	14617822
ASH2_SCHPO	ash2	physical	14617822
SWD1_SCHPO	swd1	physical	14617822
SWD2_SCHPO	swd2	physical	14617822
SWD3_SCHPO	swd3	physical	14617822
SHG1_SCHPO	shg1	physical	14617822
YO48_SCHPO	SPBC36B7.08c	genetic	18818364
EIF2A_SCHPO	SPBC4B4.04	genetic	18818364
UBP3_SCHPO	ubp3	genetic	18818364
RPA12_SCHPO	rpa12	genetic	18818364
URK1_SCHPO	SPCC162.11c	genetic	18818364
2AD1_SCHPO	par1	genetic	18818364
AAKB_SCHPO	amk2	genetic	18818364
BMT5_SCHPO	SPCC1919.13c	genetic	18818364
NUP60_SCHPO	nup60	genetic	18818364
CCR4_SCHPO	ccr4	genetic	18818364
MU154_SCHPO	mug154	genetic	18818364
RAF1_SCHPO	raf1	genetic	18818364
JHD1_SCHPO	epe1	genetic	18818364
VPH2_SCHPO	vph2	genetic	18818364
RAF2_SCHPO	raf2	genetic	18818364
SET1_SCHPO	set1	genetic	18818364
SPP1_SCHPO	spf1	genetic	18818364
COX19_SCHPO	SPCC1672.04c	genetic	22681890
DPH2_SCHPO	dph2	genetic	22681890
MU146_SCHPO	mug146	genetic	22681890
YCRE_SCHPO	trs130	genetic	22681890
YAV5_SCHPO	SPAC27F1.05c	genetic	22681890
YJCD_SCHPO	SPCC736.13	genetic	22681890
NU132_SCHPO	nup132	genetic	22681890
YEKI_SCHPO	nup37	genetic	22681890
SPO4_SCHPO	spo4	genetic	22681890
YDPH_SCHPO	SPAC29A4.17c	genetic	22681890
TCO89_SCHPO	tco89	genetic	22681890
FIN1_SCHPO	fin1	genetic	22681890
SWR1_SCHPO	swr1	genetic	22681890
FIS1_SCHPO	fis1	genetic	22681890
PPX1_SCHPO	SPAC2F3.11	genetic	22681890
REC16_SCHPO	rep1	genetic	22681890
GST3_SCHPO	gst3	genetic	22681890
MRM1_SCHPO	mrm1	genetic	22681890
YD1K_SCHPO	SPAC4G9.20c	genetic	22681890
PAC2_SCHPO	pac2	genetic	22681890
YNU4_SCHPO	SPBC28E12.04	genetic	22681890
YH51_SCHPO	SPBC215.01	genetic	22681890
CEK1_SCHPO	cek1	genetic	22681890
EIF2A_SCHPO	SPBC4B4.04	genetic	22681890
VAM7_SCHPO	SPCC594.06c	genetic	22681890
YAM3_SCHPO	SPAC1F5.03c	genetic	22681890
LYS1_SCHPO	lys3	genetic	22681890
SEH1_SCHPO	seh1	genetic	22681890
IMA3_SCHPO	SPCC550.11	genetic	22681890
SHE9_SCHPO	SPAC823.13c	genetic	22681890
MED19_SCHPO	rox3	genetic	22681890
RS3_SCHPO	rps3	genetic	22681890
ARF6_SCHPO	arf6	genetic	22681890
UBP8_SCHPO	ubp8	genetic	22681890
YAC5_SCHPO	cph1	genetic	22681890
UFD2_SCHPO	ufd2	genetic	22681890
AP2M_SCHPO	apm4	genetic	22681890
DBR1_SCHPO	dbr1	genetic	22681890
RAD55_SCHPO	rad55	genetic	22681890
YJ44_SCHPO	SPCC70.04c	genetic	22681890
YIW4_SCHPO	SPAC694.04c	genetic	22681890
PLB2_SCHPO	SPAC1A6.03c	genetic	22681890
YF69_SCHPO	SPAC23C4.09c	genetic	22681890
MTNA_SCHPO	SPBC23E6.10c	genetic	22681890
YGN3_SCHPO	SPBC2D10.03c	genetic	22681890
FEP1_SCHPO	fep1	genetic	22681890
YK82_SCHPO	bdf2	genetic	22681890
CCQ1_SCHPO	ccq1	genetic	22681890
RPA12_SCHPO	rpa12	genetic	22681890
PYR1_SCHPO	ura1	genetic	22681890
MUG30_SCHPO	mug30	genetic	22681890
MBO1_SCHPO	mto1	genetic	22681890
PNC1_SCHPO	pnc1	genetic	22681890
MDE2_SCHPO	mde2	genetic	22681890
YI06_SCHPO	SPAC869.06c	genetic	22681890
FUS1_SCHPO	fus1	genetic	22681890
YE08_SCHPO	SPAC17H9.08	genetic	22681890
YGBA_SCHPO	SPBC25B2.10	genetic	22681890
GCN5_SCHPO	gcn5	genetic	22681890
SWD1_SCHPO	swd1	genetic	22681890
YDZF_SCHPO	SPAC14C4.15c	genetic	22681890
MU113_SCHPO	mug113	genetic	22681890
ZIP1_SCHPO	zip1	genetic	22681890
DYLT_SCHPO	dlc1	genetic	22681890
CWF17_SCHPO	spf38	genetic	22681890
MAL3_SCHPO	mal3	genetic	22681890
YAQD_SCHPO	SPAC18G6.13	genetic	22681890
OYEA_SCHPO	SPAC5H10.04	genetic	22681890
TMA20_SCHPO	tma20	genetic	22681890
MUG80_SCHPO	mug80	genetic	22681890
KA113_SCHPO	kap113	genetic	22681890
GAS5_SCHPO	gas5	genetic	22681890
GCN1_SCHPO	SPAC18G6.05c	genetic	22681890
PPK30_SCHPO	ppk30	genetic	22681890
YC8F_SCHPO	SPCC622.15c	genetic	22681890
ARP42_SCHPO	arp42	genetic	22681890
UBX2_SCHPO	ubx2	genetic	22681890
SET3_SCHPO	set3	genetic	22681890
YCL3_SCHPO	SPCC16A11.03c	genetic	22681890
SPT2_SCHPO	spt2	genetic	22681890
YC7B_SCHPO	SPCC417.11c	genetic	22681890
MSC1_SCHPO	msc1	genetic	22681890
YOFE_SCHPO	SPBP4H10.14c	genetic	22681890
ASH2_SCHPO	ash2	genetic	22681890
POF9_SCHPO	pof9	genetic	22681890
YKN2_SCHPO	SPAPB1A11.02	genetic	22681890
YJ23_SCHPO	SPCC4B3.03c	genetic	22681890
HIS7_SCHPO	his5	genetic	22681890
MUG93_SCHPO	mug93	genetic	22681890
YGID_SCHPO	SPBC2A9.13	genetic	22681890
ATIF_SCHPO	SPCC70.02c	genetic	22681890
HIBCH_SCHPO	snr1	genetic	22681890
VPS38_SCHPO	vps38	genetic	22681890
YKQC_SCHPO	SPAC688.12c	genetic	22681890
SET11_SCHPO	set11	genetic	22681890
CTL1_SCHPO	ctl1	genetic	22681890
NU124_SCHPO	nup124	genetic	22681890
YI7F_SCHPO	SPAC977.15	genetic	22681890
JHD1_SCHPO	epe1	genetic	22681890
ATG16_SCHPO	atg16	genetic	22681890
TLS1_SCHPO	tls1	genetic	22681890
YOI9_SCHPO	SPBC1778.09	genetic	22681890
SNT2_SCHPO	snt2	genetic	22681890
COQ10_SCHPO	coq10	genetic	22681890
MMS19_SCHPO	mms19	genetic	22681890
LIZ1_SCHPO	liz1	genetic	22681890
YO48_SCHPO	SPBC36B7.08c	genetic	22681890
ATP14_SCHPO	atp14	genetic	22681890
ATP5E_SCHPO	atp15	genetic	22681890
YB35_SCHPO	SPBC2F12.05c	genetic	22681890
YCF8_SCHPO	SPCC1393.08	genetic	22681890
YGS9_SCHPO	tri1	genetic	22681890
MDV1_SCHPO	caf4	genetic	22681890
ABC2_SCHPO	abc2	genetic	22681890
RM01_SCHPO	SPAC1610.02c	genetic	22681890
GAR2_SCHPO	gar2	genetic	22681890
YBKD_SCHPO	gmh6	genetic	22681890
MST2_SCHPO	mst2	genetic	22681890
YA7D_SCHPO	SPAC24H6.13	genetic	22681890
TYW4_SCHPO	SPBC19C7.08c	genetic	22681890
YQ9H_SCHPO	SPCC18.17c	genetic	22681890
SET1_SCHPO	set1	genetic	22681890
RENT1_SCHPO	upf1	genetic	22681890
TSR4_SCHPO	SPBC25H2.15	genetic	22681890
PPK16_SCHPO	ppk16	genetic	22681890
IQW1_SCHPO	iqw1	genetic	22681890
YBPD_SCHPO	SPBC16H5.13	genetic	22681890
RGA5_SCHPO	rga5	genetic	22681890
SVP26_SCHPO	SPCC1795.10c	genetic	22681890
DAD2_SCHPO	dad2	genetic	22681890
SIF3_SCHPO	sif3	genetic	22681890
POF15_SCHPO	pof15	genetic	22681890
YA99_SCHPO	SPAC13G6.09	genetic	22681890
H2AZ_SCHPO	pht1	genetic	22681890
PPK25_SCHPO	ppk25	genetic	22681890
PDE1_SCHPO	cgs2	genetic	22681890
TIP1_SCHPO	tip1	genetic	22681890
YG0C_SCHPO	SPBC1604.12	genetic	22681890
YDJ7_SCHPO	SPAC57A10.07	genetic	22681890
MID1_SCHPO	mid1	genetic	22681890
YOH8_SCHPO	leo1	genetic	22681890
BSCLH_SCHPO	SPAC3A11.04	genetic	22681890
MU154_SCHPO	mug154	genetic	22681890
YG41_SCHPO	cxr1	genetic	22681890
RL9A_SCHPO	rpl901	genetic	22681890
STB3_SCHPO	SPBC1652.01	genetic	22681890
PDC4_SCHPO	SPAC3G9.11c	genetic	22681890
KCAB_SCHPO	osr2	genetic	22681890
MCL1_SCHPO	mcl1	genetic	22681890
GPD2_SCHPO	gpd2	genetic	22681890
RF1M_SCHPO	mrf1	genetic	22681890
YGT9_SCHPO	SPBC4C3.09	genetic	22681890
YOX1_SCHPO	yox1	genetic	22681890
YQC8_SCHPO	SPCC1739.08c	genetic	22681890
SEC74_SCHPO	sec74	genetic	22681890
YEAA_SCHPO	SPACUNK4.10	genetic	22681890
RGA8_SCHPO	rga8	genetic	22681890
YKT8_SCHPO	SPAPB1E7.08c	genetic	22681890
MUG73_SCHPO	mug73	genetic	22681890
ORC2_SCHPO	orc2	physical	23695164
ORC2_SCHPO	orc2	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SWD3_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-379, AND MASSSPECTROMETRY.	18257517 [Abstract]