SPO4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SPO4_SCHPO
• UniProt AC: Q9UQY9
• Protein Name: Cell cycle protein kinase spo4
• Gene Name: spo4
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 429
• Subcellular Localization: Nucleus .
• Protein Description: Required for the initiation of meiosis II and progression through anaphase II..
• Protein Sequence: MLSMLLPFGNSGVYASDVDREDRPEIAKLVQAFPTIEEDYHVVKLVGAGSFSSVFKAVDRHFDSYDNSYWISSQIEDQMPHDKTKRPKNHFVALKRIYATVLPSRIQTELEMLHELRGSDCVLNMITAVRHQDQVLIVLPFIQHAEFRDFYMKYSLPEIGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQWQEADAPTENCCVDKLRKLKQEGKYYDYFPFEKTIADPPEGYLLHDPRPTKRADRAGTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFRCEDDIDAIVELAHIFGRNGMSNCALLHGQIWSDNIPTLLDQKHNWLDLIASITKNDENLILETSSDYQVALAIDLLDKLLELHPSKRVKAKTALQHEFFNACGVTRSGFEAENPFRSDFPSTVEQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
264	Phosphorylation	KRADRAGTRGFRAPE CCCCCCCCCCCCCHH	27.00	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SPO4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SPO4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SPO4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPO6_SCHPO	spo6	physical	11739743
SWD3_SCHPO	swd3	genetic	22681890
EXG1_SCHPO	exg1	genetic	22681890
MID1_SCHPO	mid1	genetic	22681890
CDK1_SCHPO	cdc2	genetic	23370392

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.