GST3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GST3_SCHPO
• UniProt AC: Q9P6M1
• Protein Name: Glutathione S-transferase 3
• Gene Name: gst3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 242
• Subcellular Localization: Cytoplasm .
• Protein Description: May have a role in the detoxification of various heavy metals..
• Protein Sequence: MIVLHHLKNSRSTRIVWMLEELKVPYEIKVYDRVDGRAPPAYTKLSPLGKSPIVVDDGVTYIESAAILEHLVRKYGPSFKPSEEDVAELEKYELWMHFSEASLMPFIWASHVLDLSVNMTPIFFRYIVRQFVNGIKSKYLSKETFLNLDYIDNHLASNEYFAGEQFTAADPQMCFPIFAAQRDYLSQKPYKNIKRWMRVVSDRPACRIAAEKVEDNTLTLFSDVERYSHPPTPPPEQVRSDE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
217	Phosphorylation	AEKVEDNTLTLFSDV EEECCCCEEEEECCH	33.18	29996109
219	Phosphorylation	KVEDNTLTLFSDVER ECCCCEEEEECCHHH	24.58	21712547
222	Phosphorylation	DNTLTLFSDVERYSH CCEEEEECCHHHHCC	43.81	29996109
227	Phosphorylation	LFSDVERYSHPPTPP EECCHHHHCCCCCCC	9.60	21712547
228	Phosphorylation	FSDVERYSHPPTPPP ECCHHHHCCCCCCCH	35.42	28889911
232	Phosphorylation	ERYSHPPTPPPEQVR HHHCCCCCCCHHHHC	53.53	28889911
240	Phosphorylation	PPPEQVRSDE----- CCHHHHCCCC-----	47.43	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GST3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GST3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GST3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GST3_SCHPO	gst3	physical	12063243

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-228 AND THR-232, ANDMASS SPECTROMETRY.
PubMed: 18257517