dbPTM

YKT8_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YKT8_SCHPO
UniProt AC	Q9C101
Protein Name	Uncharacterized MFS-type transporter PB1E7.08c
Gene Name	SPAPB1E7.08c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	554
Subcellular Localization	Endoplasmic reticulum . Membrane Multi-pass membrane protein .
Protein Description
Protein Sequence	MSSSIPPRLYDMSPTESKKQEDVSETELVYPVELADATIQPSKSDDDLFDSNDFSKTYLAKSRILSNAMNEIGFGRYQWYLFFVAGFGWMSDNIWPVCTSLILMRLDEVDGPHPPAEGRAPYLTLSQNLGLLVGAMVWSLSADTIGRRWAFNLTFLFTGVFAVIAGASPNFASICVFDALWSFGVGGNLPVDSAIFLEALPSSHQWLLTVMSFWWAIGQVIANLVSWGLISNFSCPDDESVCHRADNKGWRYFLFTMGGMTLLMFAARFLVSVYESPKFYLAKGDDYKAVETIHKIARINGKTCTLTVEELYAIDRQEQEESDLDDSKSSDAKSVTQGTTNLIVEKLRKYNFEHIRQCFGSRKLAISSILVILSWAVIGLAFPLYNAFLPYYLETRGNANEPLSVAKTYRNSLIVSAIGVPGSLIAGVLVEFRIGRKGTLCLSLILTGVFLFASTTAKTSNAYLGWNCTFSFFSDIMYGVLYAYTPEVFPSKVRGTAVGLAASANRILGIFSPVIAMRANLTTSAPIFVSGALFIFAGILVVFFPYEPRGKSSF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	PPRLYDMSPTESKKQ CCCCCCCCCCCCCCC	26.27	28889911
15	Phosphorylation	RLYDMSPTESKKQED CCCCCCCCCCCCCCC	45.65	29996109
17	Phosphorylation	YDMSPTESKKQEDVS CCCCCCCCCCCCCCC	47.86	29996109
24	Phosphorylation	SKKQEDVSETELVYP CCCCCCCCCCEEEEE	51.64	24763107
26	Phosphorylation	KQEDVSETELVYPVE CCCCCCCCEEEEEHH	27.41	29996109
44	Phosphorylation	ATIQPSKSDDDLFDS CEECCCCCCCCCCCC	51.08	21712547
322	Phosphorylation	DRQEQEESDLDDSKS HHHHHHCCCCCCCCC	42.60	29996109
334	Phosphorylation	SKSSDAKSVTQGTTN CCCCCCCHHCCHHHH	31.92	28889911
336	Phosphorylation	SSDAKSVTQGTTNLI CCCCCHHCCHHHHHH	28.50	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YKT8_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YKT8_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YKT8_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YKT8_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YKT8_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13 AND SER-334, AND MASSSPECTROMETRY.	18257517 [Abstract]