| UniProt ID | CCQ1_SCHPO | |
|---|---|---|
| UniProt AC | Q10432 | |
| Protein Name | Coiled-coil quantitatively-enriched protein 1 | |
| Gene Name | ccq1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 735 | |
| Subcellular Localization | Nucleus, nucleoplasm. Chromosome, telomere. Associates with major heterochromatin, sub-telomeres, rDNA and the mat locus. | |
| Protein Description | Component of the meiotic bouquet that facilitates meiotic nuclear reorganization of the telomeres to the centrosome. Links telomeres to the meiotic centrosome component pcp1. Essential for the formation of normal telomere clusters during meiotic prophase. Required for telomere length regulation and chromosome segregation. Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).. | |
| Protein Sequence | MSEINDFTNSIIINESDTKYEVYSEVNSSNRWIAKEDCPSPLEDVWLLKLAGHKRKLEEPLSCMRNEEPASKQREIEKFLRTDLDHSENDFLTQEVDEFPSTQQLFPIPLQNDTAFDSSEESITKSSKSSFSVLDIGLPMSALQRKMMHRLVQYFAFCIDHFCTGPSDSRIQEKIRLFIQSAHNIAKHPSLYDTEVRNPSAAESTNSHVSLDASNFSSYAENSSKFLFLQELFKNLSPSYSKTFFLFISNQFLANTLTQWLKSQNIDAELWAEEDAKTSQHPAIWICVSKKAPSASHFLQSCPDLSATIFYDIEAYMSVTSSLPSIQSLVLRLIHLGSIEHAIKCFQSSYNASFLVNIVGVVATLSSSSEENSEASNLSTLFEKSGNFEEILGSESHSSITEKTRDIAKNVATWLKNGENFSSWPLPPLMDLASLSVAEPRDSQPSVSQVNDTFVKSSDSTFPSSQSMQSPSKLHSLTSNATDLLSSSSLKKNFFSQQEADEVELSNNYDLQGAAVQYLQRRLRMVEDELHEAINSKNVQQSRSEELEQQISKLTDNLQEYRNTVRELKLDLEKSKKKNEDLSKLEVEKVEEIANLKKELTHLAKQQEFGFKYVQEFSNEDLQGKLIEANEKNYKLTQLLKTQKEDADFITNQYQNASTFAAEQSKEVAKLQAECKRLQAINSKVMEEVKVYNDSRVEALLAKVSSLEETLKILEQKSLPKFTPHNQSPRIIDSN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 40 | Phosphorylation | IAKEDCPSPLEDVWL EECCCCCCCHHHHHH | 48.74 | 28889911 | |
| 446 | Phosphorylation | EPRDSQPSVSQVNDT CCCCCCCCHHHCCCC | 27.11 | 25720772 | |
| 465 | Phosphorylation | SDSTFPSSQSMQSPS CCCCCCCCCCCCCHH | 26.89 | 29996109 | |
| 467 | Phosphorylation | STFPSSQSMQSPSKL CCCCCCCCCCCHHHH | 22.27 | 29996109 | |
| 470 | Phosphorylation | PSSQSMQSPSKLHSL CCCCCCCCHHHHHHH | 23.62 | 24763107 | |
| 472 | Phosphorylation | SQSMQSPSKLHSLTS CCCCCCHHHHHHHCC | 53.77 | 29996109 | |
| 486 | Phosphorylation | SNATDLLSSSSLKKN CCHHHHCCCCHHHHC | 35.16 | 21712547 | |
| 487 | Phosphorylation | NATDLLSSSSLKKNF CHHHHCCCCHHHHCC | 24.74 | 21712547 | |
| 488 | Phosphorylation | ATDLLSSSSLKKNFF HHHHCCCCHHHHCCC | 35.99 | 21712547 | |
| 583 | Phosphorylation | KKKNEDLSKLEVEKV HHHCCCHHHHHHHHH | 47.73 | 29996109 | |
| 706 | Phosphorylation | ALLAKVSSLEETLKI HHHHHHHCHHHHHHH | 42.67 | 29996109 | |
| 710 | Phosphorylation | KVSSLEETLKILEQK HHHCHHHHHHHHHHC | 24.79 | 29996109 | |
| 723 | Phosphorylation | QKSLPKFTPHNQSPR HCCCCCCCCCCCCCC | 29.75 | 25720772 | |
| 728 | Phosphorylation | KFTPHNQSPRIIDSN CCCCCCCCCCCCCCC | 22.82 | 24763107 | |
| 734 | Phosphorylation | QSPRIIDSN------ CCCCCCCCC------ | 33.75 | 21712547 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CCQ1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CCQ1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CCQ1_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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