| UniProt ID | POT1_SCHPO | |
|---|---|---|
| UniProt AC | O13988 | |
| Protein Name | Protection of telomeres protein 1 | |
| Gene Name | pot1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 555 | |
| Subcellular Localization | Nucleus. Chromosome, telomere. | |
| Protein Description | Single-stranded telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang. It binds the consensus sequence 5'-GGTTAC-3'. Regulates telomerase and telomere length.. | |
| Protein Sequence | MGEDVIDSLQLNELLNAGEYKIGELTFQSIRSSQELQKKNTIVNLFGIVKDFTPSRQSLHGTKDWVTTVYLWDPTCDTSSIGLQIHLFSKQGNDLPVIKQVGQPLLLHQITLRSYRDRTQGLSKDQFRYALWPDFSSNSKDTLCPQPMPRLMKTGDKEEQFALLLNKIWDEQTNKHKNGELLSTSSARQNQTGLSYPSVSFSLLSQITPHQRCSFYAQVIKTWYSDKNFTLYVTDYTENELFFPMSPYTSSSRWRGPFGRFSIRCILWDEHDFYCRNYIKEGDYVVMKNVRTKIDHLGYLECILHGDSAKRYNMSIEKVDSEEPELNEIKSRKRLYVQNCQNGIEAVIEKLSQSQQSENPFIAHELKQTSVNEITAHVINEPASLKLTTISTILHAPLQNLLKPRKHRLRVQVVDFWPKSLTQFAVLSQPPSSYVWMFALLVRDVSNVTLPVIFFDSDAAELINSSKIQPCNLADHPQMTLQLKERLFLIWGNLEERIQHHISKGESPTLAAEDVETPWFDIYVKEYIPVIGNTKDHQSLTFLQKRWRGFGTKIV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of POT1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of POT1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of POT1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of POT1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DNLI4_SCHPO | lig4 | genetic | 18722173 | |
| RAD22_SCHPO | rad52 | genetic | 18722173 | |
| SRS2_SCHPO | srs2 | genetic | 18722173 | |
| HUS2_SCHPO | rqh1 | genetic | 18722173 | |
| CCQ1_SCHPO | ccq1 | physical | 18535244 | |
| PLI1_SCHPO | pli1 | genetic | 17209013 | |
| HUS2_SCHPO | rqh1 | genetic | 21098121 | |
| CHK1_SCHPO | chk1 | genetic | 21098121 | |
| POT1_SCHPO | pot1 | physical | 21911358 | |
| TPZ1_SCHPO | tpz1 | physical | 21911358 | |
| ATP10_SCHPO | atp10 | genetic | 22681890 | |
| YIDH_SCHPO | SPAC227.17c | genetic | 22681890 | |
| PRZ1_SCHPO | prz1 | genetic | 22681890 | |
| HUS2_SCHPO | rqh1 | genetic | 23297345 | |
| EXO1_SCHPO | exo1 | genetic | 23297345 | |
| RAD57_SCHPO | rad57 | genetic | 23297345 | |
| POT1_SCHPO | pot1 | physical | 25074378 | |
| BUB1_SCHPO | bub1 | genetic | 24469396 | |
| MAD2_SCHPO | mad2 | genetic | 24469396 | |
| CHK1_SCHPO | chk1 | genetic | 24469396 | |
| HUS2_SCHPO | rqh1 | genetic | 26465752 | |
| EXO1_SCHPO | exo1 | genetic | 26465752 | |
| CHK1_SCHPO | chk1 | genetic | 26093291 | |
| WEE1_SCHPO | wee1 | genetic | 26093291 | |
| MIK1_SCHPO | mik1 | genetic | 26093291 | |
| CDK1_SCHPO | cdc2 | genetic | 26093291 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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