NTO1_SCHPO - dbPTM
NTO1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NTO1_SCHPO
UniProt AC O74759
Protein Name Mst2 complex subunit nto1
Gene Name nto1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 767
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation..
Protein Sequence MQTFRLTSTGRNILRPDELAFQPREEIPYKSFHPDLQIDEPLEILEGDHTQYAGLRDSLVTYKSENSYVLKALLNAKIENVKPVGVQTENINPQEKKFGYKTAKQLDWSPDEYFKFVAIHPYSKTSFPVSYDLDELDTMWLTYYNEFQLSSNSEWENVSKEFLEIVLTIIEREWLYLEAWMPKIEPVRVEDELDGRCVICNEAECENSNAIVFCDNCNTSVHQNCYGIPFVPEGQWFCKKCLLAPHEVICCAFCPDRDGAFCTTLDGRWCHTICAIAIPEISFHDTSRLDLVRNIASIPKSRWKLVCCICKLRWGTCVQCSDKNCYAAYHITCARRAGFFYKIYSHSASYDSVDMETYCDKHTPPDYLNGLMKRLFPLAELYYKRMATDVPLNFQATKAPDFVPEGPWKSHPLPAFIVDKVTKVLLSYNVKRQDLPSIVTDICKFYHMKRRSRKDAPLLKSQLLMDSLENLPVRASKDRVRSLEVAKALQDQYQSLLTLVESTAKRQLLKCQLSNLRKKFLNLNYFPAQRLLQDTLVKIIDLDVDGLFNMPLDNGWIGWVELKRQVFSYQIGSISSLEKKLEPIWDVDGVIQCIDDMEQLTAMVQFAQKTEGEVKKLFIKAKIYFESLSLDERGNLKVPSLGINGLEYDNWPGLNELEMSQLDIPSQGNLKSLHDFIEGLDLNEKIGKFPISMFQNQVAQFSTIEIPKMSGRANGMHNFHSEDVTGQSNHALPNSVTKKNGTKQPYTKNSLPFNERITRSKAKKNYS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of NTO1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NTO1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NTO1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NTO1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ELOC_SCHPOSPBC1861.07genetic
18818364
SWD2_SCHPOswd2genetic
18818364
SGF29_SCHPOsgf29genetic
18818364
BDC1_SCHPObdc1genetic
18818364
NGG1_SCHPOngg1genetic
18818364
YB3C_SCHPOcay1genetic
18818364
YJ03_SCHPOrhn1genetic
18818364
SWD3_SCHPOswd3genetic
18818364
YO48_SCHPOSPBC36B7.08cgenetic
18818364
HPC2_SCHPOhip4genetic
18818364
HIF2_SCHPOhif2genetic
18818364
SDC1_SCHPOsdc1genetic
18818364
SET1_SCHPOset1genetic
18818364
SPP1_SCHPOspf1genetic
18818364
JHD1_SCHPOepe1genetic
18818364
ELP4_SCHPOelp4genetic
18818364
ERS1_SCHPOers1genetic
18818364
HRR1_SCHPOhrr1genetic
18818364
DCR1_SCHPOdcr1genetic
18818364
AGO1_SCHPOago1genetic
18818364
ELP2_SCHPOelp2genetic
18818364
ARB1_SCHPOarb1genetic
22681890
NSE6_SCHPOnse6genetic
22681890
HRP3_SCHPOhrp3genetic
22681890
BDC1_SCHPObdc1genetic
22681890
CCQ1_SCHPOccq1genetic
22681890
MTO1_SCHPOSPBC30B4.06cgenetic
22681890
CLR4_SCHPOclr4genetic
22681890
SPP1_SCHPOspf1genetic
22681890
GCN5_SCHPOgcn5genetic
22681890
SWD1_SCHPOswd1genetic
22681890
MUG80_SCHPOmug80genetic
22681890
ARP42_SCHPOarp42genetic
22681890
RAD57_SCHPOrad57genetic
22681890
JHD1_SCHPOepe1genetic
22681890
YO48_SCHPOSPBC36B7.08cgenetic
22681890
ATP14_SCHPOatp14genetic
22681890
HUS1_SCHPOhus1genetic
22681890
YIU1_SCHPOsaf5genetic
22681890
SET1_SCHPOset1genetic
22681890
PPK16_SCHPOppk16genetic
22681890
YBPD_SCHPOSPBC16H5.13genetic
22681890
FFT3_SCHPOfft3genetic
22681890
SDE2_SCHPOsde2genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
2AD2_SCHPOpar2genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
YF2C_SCHPOrrp1genetic
22681890
SGF29_SCHPOsgf29genetic
22681890

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NTO1_SCHPO

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Related Literatures of Post-Translational Modification

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