| UniProt ID | SDC1_SCHPO | |
|---|---|---|
| UniProt AC | O74861 | |
| Protein Name | Set1 complex component sdc1 | |
| Gene Name | sdc1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 109 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance.. | |
| Protein Sequence | MSNSAPARQYLNEKVTPVLLEGMKILARDRPENPLQFLGQFLLDANANQQKQKEIVNQPEPQQETPKADADMSTPTMAEQVQTSFSNPASTPLTQTSSPSSNPGKNSAS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 65 | Phosphorylation | QPEPQQETPKADADM CCCCCCCCCCCCCCC | 26.25 | 24763107 | |
| 83 | Phosphorylation | TMAEQVQTSFSNPAS HHHHHHHHHCCCCCC | 32.65 | 27738172 | |
| 94 | Phosphorylation | NPASTPLTQTSSPSS CCCCCCCCCCCCCCC | 30.88 | 27738172 | |
| 96 | Phosphorylation | ASTPLTQTSSPSSNP CCCCCCCCCCCCCCC | 26.41 | 27738172 | |
| 98 | Phosphorylation | TPLTQTSSPSSNPGK CCCCCCCCCCCCCCC | 31.99 | 29996109 | |
| 100 | Phosphorylation | LTQTSSPSSNPGKNS CCCCCCCCCCCCCCC | 44.70 | 21712547 | |
| 101 | Phosphorylation | TQTSSPSSNPGKNSA CCCCCCCCCCCCCCC | 50.88 | 27738172 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SDC1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SDC1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SDC1_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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